Clinical trials: Hospital Medicine
Sepsis
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis
Sepsis is a life-threatening disease characterized by multi-organ failure due to dysregulated host response to infection, with high global mortality of 30-50%.
- Trial name
- NCT04427371
- Testing
- the levels of pyroptosis
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jianfeng Xie
Respiratory Failure
HEAVEN Criteria: Prediction of Difficult Airway for In- Hospital Emergency Airway Management
The HEAVEN criteria were found valid to predict difficult airways during preclinical emergency intubations in a retrospective study.
- Trial name
- NCT04764799
- Testing
- Rapid sequence induction
- Where
- Switzerland
- Volunteers
- 2,800 people
- Sponsor
- Thomas Riva
Coronary Artery Disease
Promus - Registry Experience at the Washington Hospital Center, Drug-eluting Stent (DES)
Single-center registry of patients treated with at least one Promus, everolimus-eluting, Stent, with the primary objective to assess clinical success and safety at 30 days, 6 months and 1 year post-implantation.
- Trial name
- P-REWARDS (NCT01003795)
- Where
- United States
- Sponsor
- Medstar Health Research Institute
Severe Sepsis With Septic Shock, Lactate
Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients
Using sodium lactate Ringer's injection resuscitate septic shock patients and Compared with other solution, in order to make clear whether can improve the prognosis.
- Trial name
- NCT02449928
- Testing
- sodium lactate Ringer's injection(Baxter, ShangHai, China), Compound Sodium Chloride Injection (CR Double-Crane, Beijing, China)
- Sponsor
- Peking Union Medical College Hospital
Urticaria
Survey on the Characteristics of Traditional Medicine Syndromes in Urticaria Patients At Le Van Thinh Hospital
This study aims to investigate the characteristics of Traditional Medicine (TM) syndromes in urticaria patients at Le Van Thinh Hospital.
- Trial name
- NCT06859736
- Volunteers
- 150 people
- Sponsor
- Do Thanh Sang
Complications of Surgical and Medical Care: General Terms, Adverse Reaction to Drug
The Thai Surgical Intensive Care Study (Thai-SICU Study)
The study observed the 28 days mortality of 9 participated University base surgical intensive care unit (SICU) as well as the occurrence of adverse events in SICU.
- Conditions
- Complications of Surgical and Medical Care: General Terms, Adverse Reaction to Drug, Sequelae of External Causes of Morbidity and Mortality, Critical Illness
- Trial name
- THAI-SICU (NCT01354197)
- Where
- 9 sites in Thailand
- Volunteers
- 4,652 people
- Sponsor
- Royal College of Anesthesiologists of Thailand
Delirium, QT-prolongation
Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University Hospital
A prospective, observational study in a university hospital (UZ Leuven). Patients are included when they are treated with a potentional QT-prolonging drug: haloperidol for delirium, antibiotics (moxifloxacin, levofloxacin…
- Trial name
- RISQ-PATH (NCT02068170)
- Testing
- Haloperidol, azi/clari/erythromycin, levo/moxifloxacin, co-trimoxazole, vori/keto/flu/itraconazole, methadone, tacrolimus, sunitinib
- Where
- Belgium
- Volunteers
- 178 people
- Sponsor
- KU Leuven
Suicide, Attempted, Drug Use
Brief New Treatment for Suicide Attempts
Individuals with alcohol or drug use problems who are hospitalized for suicide attempt are at high risk for reattempt. This treatment development study adapts a promising outpatient intervention to prevent suicide reattempt in…
- Conditions
- Suicide, Attempted, Drug Use, Alcohol; Use, Problem
- Trial name
- NCT03300596
- Testing
- Brief intervention to prevent suicide attempt, Enhanced treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Emergency Service, Hospital, Medication Reconciliation
Medication Reconciliation in an Emergency Department: How to Prioritize Patients ?
Medication reconciliation has proven its efficiency in improving patients' care, especially for emergency patients. This study aimed to identify risk factors of unintended medication discrepancies (UMD) in an emergency…
- Trial name
- NCT03955965
- Testing
- Medication reconciliation
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph
Root Caries, Antihypertensive Drugs
Effect of Hypertensive Drugs on Root Caries Among Senior Patients in Cairo University
The aim of this analytical cross-sectional study study is to evaluate the prevalence of root caries in senior patients of both genders age of 50 to 70 years old, taking antihypertensive drugs attending the Cairo University Dental…
- Trial name
- NCT06709352
- Testing
- non
- Where
- Egypt
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Leukemia
A Retrospective Study on the Relationship Between Donor Leukocyte Telomere Length and Prognosis of Acute Leukemia Patients Treated With Allogeneic Hematopoietic Stem Cell Transplantation
This post hoc analysis included patients with acute leukemia who underwent allo-HSCT at the First Affiliated Hospital of Zhejiang University School of Medicine and Ruijin Hospital Shanghai Jiaotong University School of Medicine.
- Trial name
- NCT06076226
- Testing
- No intervention, observation study
- Where
- China
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
PCOS, Overweight
Effects of Acupuncture on Body Mass Index in Overweight and Obese Women With Polycystic Ovary Syndrome (PCOS )
This is a cross-sectional case-control study combined with a randomised controlled trial (RCT) study. This study aims to compare the effect of acupuncture, with usual care (lifestyle management) for weight control, with BMI (Body…
- Conditions
- PCOS, Overweight, Obesity
- Trial name
- PCOS (NCT04193371)
- Testing
- Active acupuncture, Lifestyle management
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome (PCOS)
Body Fat Distribution and Its Associated Factors in Chinese Women With Polycystic Ovary Syndrome
To investigate the body fat distribution in chinese women with polycystic ovary syndrome (PCOS) and the association of those distribution with metabolic parameters, microeconomics, hormone profiles and psychological state.
- Trial name
- NCT04264832
- Testing
- Clinical data collection
- Where
- China
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Palliative Medicine, Pediatric ALL
Paediatric Palliative Care Pain Management in the Community
To describe the the barriers and facilitators experienced by carers and healthcare professionals when managing medicines for pain relief for infants, children, and young people approaching the end of life in out of hospital…
- Trial name
- PARAMOUNT (NCT04519632)
- Testing
- Qualitative study
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Sickle Cell Anaemia
Mobile-Directly Observed Therapy on Adherence to Hydroxyurea
To examine the effect of mobile-directly observed therapy (mDOT) on adherence to HU (mDOT-HuA) adults with SCA at Muhimbili National Hospital (MNH) in Tanzania.
- Trial name
- mDOT (NCT02844673)
- Testing
- Hydroxyurea, Mobile Directly Observed Therapy
- Where
- Tanzania
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Muhimbili University of Health and Allied Sciences
Spinal Cord Injuries
Effect of Suctioning by Bronchoscope on Postoperative Pulmonary Complications Among Patients With SCI in the PACU
Respiratory failure and dyspnea are common in spinal cord injury (SCI), and in acute situations, any spinal cord lesion above T11 can cause abnormal respiratory function and impair the airway clearance.
- Trial name
- NCT04879602
- Testing
- suction with bronchoscopy
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pharmacists in Geriatric Health Services, Conditions Unspecified
The Pharmacist in the Acute Geriatric Inpatient Treatment Team
This trial investigates the effects of a comprehensive pharmaceutical assessment in an acute care geriatric hospital on the number of hospital readmissions and patient's days spent at home.
- Trial name
- AGITATE (NCT03412903)
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Prof. Dr. med. Cornelius Bollheimer
Hepatocellular Carcinoma
Title of Manuscript: Development and Internal-external Validation of a Comprehensive Model for Predicting Risk of Post-RFA Recurrence in HCC Patients
Background A predictive model for post radiofrequency ablation (RFA) recurrence in patients with Hepatocellular carcinoma (HCC) that incorporates variables like sleep quality and psychological factors can provide more time to…
- Trial name
- NCT06577272
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Tian'an Jiang
Intervention Study
Intervention Study on Medication Reconciliation Among Pharmacists in Two Tertiary Hospitals in Nigeria
This study will assess the current practice of medication reconciliation among pharmacists in the selected institutions with a view to making an intervention to address gaps discovered
- Trial name
- NCT03182972
- Testing
- Medication reconciliation
- Where
- 2 sites in Nigeria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Bronchiolitis, Bronchitis
Effect of AI-Assisted Discharge Education on Parents of Children With Bronchitis/Bronchiolitis
This randomized controlled trial aims to evaluate the effects of artificial intelligence-assisted discharge education on mothers of children hospitalized with bronchitis/bronchiolitis.
- Trial name
- NCT07774494
- Testing
- AI-Assisted Written Discharge Education, AI-Assisted Video Discharge Education, Routine Discharge Education
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University