Clinical trials: Hospital Medicine
Hospitalized Patient
Interest of Drug Reconciliation to Ensure the Continuity of the Treatment at Discharge
From a regulatory point of view, medication reconciliation is a necessary process to ensure safe medication management for patients.
- Trial name
- ICOCON (NCT05062655)
- Testing
- Drug reconciliation
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier le Mans
Acute Illness Requiring to Hospital Telemetry Admission
A Study of Physiologic Changes in a Telemetry Unit
The purpose of this study is to determine the physiological changes associated with health deterioration, as well as different types, doses, and routes of administration of medications and fluids in acutely ill patients.
- Trial name
- NCT05534516
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Tracheal Intubation Morbidity
Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique
The purpose of this study is to evaluate intubation duration between rapid sequence intubation technique (RSI) and non-rapid sequence intubation technique (non-RSI) performed by emergency medicine residents in Siriraj hospital.
- Trial name
- NCT01474252
- Testing
- RSI
- Where
- Thailand
- Volunteers
- 224 people
- Sponsor
- Siriraj Hospital
Intrathecal Pump Refill
Intrathecal Pump Refills at Home or at the Hospital
The IMPROVE study is a randomized, controlled, cross-over trial designed to compare intrathecal pump refills performed at home with those carried out in the hospital.
- Trial name
- IMPROVE (NCT07727798)
- Testing
- Refill at the hospital, Refill at home
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Moens Maarten
Severe Acute Malnutrition, Health Care Associated Infection
Prevention of Nosocomial Infections (CleanKids)
While the standardization of treatment protocols for Severe Acute Malnutrition (SAM) has helped to reduce historically high mortality, mortality in inpatient settings remains substantial, likely due to the severity of…
- Conditions
- Severe Acute Malnutrition, Health Care Associated Infection, Multi Drug Resistant Organisms
- Trial name
- CleanKids (NCT03360877)
- Testing
- Health-care associated infection (HCAI)
- Volunteers
- 4,944 people
- Sponsor
- Epicentre
Chemotherapeutic Toxicity
Residual Neuromuscular Block of Rocuronium in Chemotherapy Patients Under Sevoflurane Anesthesia
Chemotherapy causes motor nerve dysfunction and degeneration that may alter the response to neuromuscular blocking drugs. To analyse the risk of residual neuromuscular block (RNMB) induced by rocuronium given in standard doses to…
- Trial name
- NCT04965532
- Testing
- sevoflurane anesthesia, Propofol Injection
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Shock, Coronary Heart Disease
Safety Study of Shenmai(a Chinese Medicine Injection) Used in Hospitals in China
The purpose of this study is to make a cohort event monitoring to see whether and how Shenmai injection in hospital results in adverse events or adverse drug reactions.
- Trial name
- NCT01612611
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Infectious Disease
Antibiotic Outbreak, Risk Factors for Never Event, Prediction of Inappropriate Use
In order to decrease inappropriate antibiotic use, drivers of inappropriate use must be identified locally. This study will focus on the MOST inappropriate use, which are defined as 'never events'.
- Trial name
- NCT03489330
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00019864
- Testing
- filgrastim, cisplatin, dexrazoxane hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Infection Viral, Infection, Hospital
Early Risk Stratification of Patient Hospitalized for SARS-CoV2 Infection: Critical COVID-19 France CCF
The COVID-19 pandemic of SARS CoV2 (Severe Acute Respiratory Syndrome, COVID-19) infection, which is currently evolving in France, raises many questions about the clinical and biological profile of infected hospitalized patients.
- Conditions
- Infection Viral, Infection, Hospital, COVID
- Trial name
- CCF (NCT04344327)
- Where
- 23 sites in France
- Volunteers
- 2,878 people
- Sponsor
- French Cardiology Society
Elderly
Using Clinical Alerts to Decrease Inappropriate Medication Prescribing
Introduction: The Beers list identifies medications that should be avoided in persons 65 years or older because they are ineffective, pose an unnecessarily high risk, or a safer alternative is available.
- Trial name
- NCT01034761
- Testing
- Pop-up alert
- Where
- United States
- Volunteers
- 719 people
- Sponsor
- Baystate Medical Center
Cancer
Examining the Feasibility and Impact of a Clinic-based Food Farmacy and Digital Culinary Medicine Program Among Cancer Survivors Treated in a Safety Net Hospital
The goal of this study is to develop and test the feasibility of a theory-driven digital culinary medicine program among food insecure cancer survivors referred from the University of Texas MD Anderson Cancer Center Oncology…
- Trial name
- NCT06760754
- Testing
- Digital culinary medicine intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Haemodialysis
Comparison Between Haparin and Herodin in HD
The goal of this study is to compare the efficacy and drawbacks of Heparin and Hirudin in Haemodialysis patients. The main question it aims to answer is: which drug is more safe in Haemodialysis?
- Trial name
- NCT06112262
- Testing
- Heparin
- Volunteers
- 98 people
- Sponsor
- Basma Rabiey
Patient Acceptance of Health Care, Acute Renal Failure
DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Hospital Patients
Current evidence shows that computerized decision support systems (CDSS) have shown to be insufficiently effective to prevent adverse drug reactions (ADRs) at large scale (e.g. whole hospital).
- Trial name
- DETECT-IP: (NCT05923983)
- Testing
- Clinical decision support, Will not receive Clinical Decision Support
- Where
- France
- Volunteers
- 783 people
- Sponsor
- University Hospital, Lille
Out-of-hospital Cardiac Arrest
German Cardiac Arrest Registry
In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes.
- Trial name
- G-CAR (NCT05142124)
- Where
- 25 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Leipzig Heart Science gGmbH
Polytrauma
Comparing Trauma Severity Scores Injury Severity Score "ISS", Rapid Emergency Medicine Score "REMS" and Kampala Trauma Score "KTS"
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading…
- Trial name
- NCT05544773
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assiut University
Helicobacter Pylori Infection
ILTHPI - Comparison of Medicament Containing Tetracycline, Metronidazole, Bismuth Versus Amoxicillin, Metronidazole, Clarithromycin
Helicobacter pylori (H. pylori) is a spiral shaped, microaerophilic, gram negative bacterium. The organism resides in the acid and mucous layer of the human gastric mucosa, adheres to and colonizes the mucosal surface of the…
- Trial name
- NCT04853875
- Testing
- Tetracycline, Metronidazole, Bismuth subcitrate, Amoxicillin, Metronidazole, Clarithromycin
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Mackay Memorial Hospital
Pain, Acute Pain
Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.
Pain is a symptom that drives hospital admissions, and pain management is required by most patients during their hospital stay. Further, the use of medications such as opioids can lead to upward-spiraling doses, especially among…
- Conditions
- Pain, Acute Pain, Postoperative Pain
- Trial name
- NCT02470728
- Testing
- New Clinical Pathway
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Crohn Disease
The Effects of Parenteral ω-3 Polyunsaturated Fatty Acid on Postoperative Complications of Patients With Crohn's Disease
This study is intended to investigate the safety and efficacy of ω-3 polyunsaturated fatty acid-based parenteral nutrition (PN) for patients with Crohn's disease.
- Trial name
- ω3CD (NCT03901937)
- Testing
- ω-3 polyunsaturated fatty acid, Intestinal surgery for Crohn's Disease
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Sir Run Run Shaw Hospital
Age Problem
Impact of a Hospital Medication Expertise on Unplanned Hospitalizations at 3 Months of Nursing Homes Patients
The use of drugs in the elderly population remains a major public health problem worldwide. Technological advances and the development of new drugs have helped to extend life expectancy.
- Trial name
- TEM-EHPAD (NCT03640845)
- Testing
- tele-expertise
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Assistance Publique Hopitaux De Marseille