Clinical trials: Hospital Medicine
Perioperatoire Medicine, Surgery
Evaluation of a Structured Hospital-Community Care Follow-up Based on Perceived Quality of Care After Surgery, Aimed at Reducing Persistent Opioid Use in Primary Care: a Pragmatic Randomized Controlled Trial
The OPTIMISTE program is based on a structured postoperative follow-up centered on patients' subjective perception of recovery using validated Patient Reported Outcome Measures (PROMs), including the mQoR-15f score.
- Trial name
- OPIOID CITY FR (NCT07659730)
- Testing
- Patient-Reported Outcomes-based perioperative follow-up (QoR-15 focus)
- Volunteers
- 772 people
- Sponsor
- University Hospital, Strasbourg, France
Increased Drug Resistance
Antimicrobial Resistance in Hospitals From Meta, Colombia
Introduction: Healthcare-associated infections cause a burden in morbidity and mortality, and they increase the financial cost of care.
- Trial name
- NCT06044272
- Testing
- Factors associated
- Where
- Colombia
- Volunteers
- 10,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Rheumatoid Arthritis
Study to Describe Real World Drug Retention Rate of the Tocilizumab at One Year
This multicenter, prospective, non-interventional study is designed to obtain an accurate estimation of the drug retention rate of Tocilizumab (TCZ) Subcutaneously (SC) under real-world conditions in participants with moderate to…
- Trial name
- NCT02608112
- Testing
- Methotrexate, Tocilizumab
- Where
- 77 sites in France
- Volunteers
- 291 people
- Sponsor
- Hoffmann-La Roche
Occupational Stress or Workplace Stress, Exhaustion, Caregiver
Feasibility of Body Acupuncture for Stress, Burnout, Sleep Quality and Wellbeing: A Pilot Study
This pilot study investigates the acceptability and effects of traditional Chinese medicine (TCM) body acupuncture on stress and exhaustion among healthcare professionals working in an acute care hospital.
- Trial name
- TCM-ACU-PILOT (NCT07818837)
- Testing
- Traditional Chinese Medicine Body Acupuncture
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss University for Traditional Chinese Medicine
Cough Severity, Cough Frequency
Clinical Trial Evaluate the Cough-relieving and Expectorant Effects of the Health Supplement AZKA Nasal and Throat for Children in Outpatient-treated Pharyngitis
This is a randomized, open-label, single-center clinical trial evaluating the efficacy and safety of Azka Nasal and Throat for Children compared to the control drug Prospan Cough Syrup in children aged 4-6 years diagnosed with…
- Conditions
- Cough Severity, Cough Frequency, Cough Duration, Phlegm Accumulation (Nasal and Throat Mucus)
- Trial name
- AZKA (NCT06761339)
- Testing
- Azka Nasal and Throat for Children, Prospan cough Syrup
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Internal Medicine
Polypharmacy Among Internal Medicine Patients
The World Health Organisation Patient Safety Challenge: Medication Without Harm has brought our attention to the importance of medication-related harm as a global public health issue.
- Trial name
- NCT05756400
- Where
- Iceland
- Volunteers
- 85,942 people
- Sponsor
- University of Iceland
Staphylococcus Aureus
Antimicrobial Drug Use and Resistant Staphylococcus Aureus
The purpose of this investigation is to study the relationships between antimicrobial stewardship program efforts, antimicrobial drug use, and infection control efforts to the incidence rates of hospital acquired infections with…
- Trial name
- NCT01075451
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Severe Infection
Chinese PICU Collaborative Network on Pathogens and Drug Resistance of Severe Infections
To investigate PICUs in major cities in China by establishing a high-quality standardized clinical database of PICU inpatients Incidence, fatality rate, pathogen distribution, anti-infective treatment of…
- Trial name
- NCT04923828
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Children's Hospital of Fudan University
Multimorbidity, Polypharmacy
OPTImization of Medication by Transdisciplinary Assessment of Drug Treatment in Elderly Hospitalized Patients
This study is being done to find out if a multi-faceted intervention designed to optimize medication in hospitalized older people with multiple chronic medical conditions exposed to multiple medications can reduce unplanned…
- Trial name
- OPTIMATE (NCT05387096)
- Testing
- Definitive multi-faceted intervention consisting of several components
- Where
- 3 sites in Belgium, Ireland
- Volunteers
- 642 people
- Sponsor
- University College Cork
Opioid Use, Pain, Musculoskeletal
Naloxone Education in Total Joint Patients
This study examines the efficacy of a brief pre-hospital naloxone education module added to the standard "Total Joint Class" curriculum on patient safety and experience.
- Conditions
- Opioid Use, Pain, Musculoskeletal, Surgery, Overdose of Opiate
- Trial name
- NCT04868552
- Testing
- Pre-hospital naloxone education
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Carilion Clinic
Wounds and Injuries, Out-of-Hospital Cardiac Arrest
Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest
This retrospective population-based cohort study uses linked administrative healthcare data from the Local Health Authority of Bologna (Italy) to describe the use of four classes of psychoactive drugs (opioids, antiepileptics…
- Conditions
- Wounds and Injuries, Out-of-Hospital Cardiac Arrest, Traumatic Brain Injury
- Trial name
- LIFT-C (NCT07882589)
- Testing
- Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A)
- Where
- 2 sites in Italy
- Volunteers
- 52,720 people
- Sponsor
- Azienda Usl di Bologna
Diabetes Mellitus, Type 2, Adherence, Medication
Adherence and Beliefs About Medications, and Illness Perception Among Type 2 Diabetic Patients in Assiut Main Hospital
Diabetes mellitus (DM) is considered one of the oldest fast-growing publichealth problems. It's a chronic metabolic disorder characterized mainly by highlevel of glucose level, associated globally with increased morbidity…
- Trial name
- NCT05301855
- Where
- Egypt
- Volunteers
- 417 people
- Sponsor
- Assiut University
Postoperative Recovery
Association of Perioperative Daily Steps and Postoperative Recovery Among Surgical Patients
Walking is the most common, simple and convenient way of exercise with the lowest cost. Studies have shown that daily steps are related to important health outcomes such as cardiovascular events and all-cause mortality.
- Trial name
- NCT04934657
- Testing
- no intervention
- Where
- China
- Volunteers
- 487 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bone Diseases
Free Nonvascularized Fibula Autograft for Tumor-like Lesions in Femoral Neck Using in Pediatric Patients
This study was to evaluate the safety and efficacy of free nonvascularized fibula autograft in the treatment of the femoral neck tumor-like lesions before epiphyseal closure in pediatric patients, by presenting the…
- Trial name
- NCT03129230
- Testing
- free nonvascularized fibula autograft
- Where
- 2 sites in China
- Volunteers
- 16 people
- Sponsor
- Yulin Orthopedics Hospital of Chinese and Western Medicine
HIV, AIDS
Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug Users
Primary Objective: This study will evaluate the most effective strategy in achieving HIV virologic suppression among HIV-infected substance users recruited from the hospital setting who are randomly assigned to one of three…
- Conditions
- HIV, AIDS, Substance Abuse, Inpatient
- Trial name
- CTN0049 (NCT01612169)
- Testing
- Patient Navigation (PN) Group, Patient Navigator Plus Contingency Management (PN+CM) Group
- Where
- 12 sites in United States
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- Columbia University
Renal Dialysis, Health Literacy Level
Impact of Hospital Pharmacist Intervention on Medication Management in Dialysis Patients
The goal of this clinical trial is to learn if an intervention of a hospital pharmacist could help, dialysis patients managed his treatment. In a first time, the health literacy level will be assed.
- Conditions
- Renal Dialysis, Health Literacy Level, Kidney Disease, Chronic
- Trial name
- IPhaDia (NCT06692231)
- Testing
- Pharmacist intervention
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier de Vichy
Viral Pneumonia, Bronchitis
A Registry Study on Xiyanping(a Chinese Medicine Injection) Used in Fifty Hospitals
This study was advocated by Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences in October 2011.
- Conditions
- Viral Pneumonia, Bronchitis, Infantile Diarrhea, Bacillary Dysentery
- Trial name
- NCT01612572
- Volunteers
- 20,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Data From Danish Cardiac Arrest Registry
Out-of-hospital cardiac arrest is a leading cause of death worldwide and patient outcome vary substantially throughout regions suggesting further evaluation and potential for improvement.When focussing on subgroups of OHCA, data…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Trauma, Drug Overdose, Electrocution
- Trial name
- NCT05308303
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Postoperative Hyperalgesia
Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery
Postoperative hyperalgesia (POH) is a paradoxical clinical state of increased sensation of pain or increased sensitivity to non-painful stimuli at the site of surgery or at a surrounding area that was not directly injured.
- Trial name
- NCT05016128
- Testing
- S-ketamine, saline
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Out-of-hospital Cardiac Arrest (OHCA)
Impact of Low Dose Epinephrine in the Management of Out-of-hospital Cardiac Arrest on Neurological Outcome
This study will test whether a lower dose of epinephrine (0.5 mg) given during emergency treatment for out-of-hospital cardiac arrest helps more patients survive with good brain function, compared to the standard dose (1 mg).
- Trial name
- Low-EPI (NCT07442071)
- Testing
- Epinephrine 0.5 mg intravenous bolus, Epinephrine 1 mg intravenous bolus
- Where
- 26 sites in France
- Volunteers
- 4,336 people
- Sponsor
- Central Hospital, Nancy, France