Clinical trials: Hospital Medicine
Rectal Cancer, Adjuvant Chemoradiotherapy
Observational Study on the Patients With Rectal Cancer
The aim of this observational study is to retrospectively collect current survival data for 3995 primary rectal cancer patients who were extracted from 5097 rectal cancer patients admitted in Cancer Hospital, Chinese Academy of…
- Conditions
- Rectal Cancer, Adjuvant Chemoradiotherapy, Neoadjuvant Chemoradiotherapy, Adjuvant Chemotherapy
- Trial name
- NCT02312284
- Where
- China
- Volunteers
- 3,995 people
- Sponsor
- Chinese Academy of Medical Sciences
Recruitment
Chinese Regional Spinal Muscular Atrophy Patient Registration Study
The primary objectives of this study are to obtain clinically meaningful data on the survival, outcomes, prognosis and treatment effect of all the patients with spinal muscular atrophy (SMA) 5q types 1 to 3 (according to…
- Trial name
- NCT05631418
- Where
- China
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Chronic Disease
Optimizing Medication Therapy for Patients Recently Discharged From Hospital
Patients who are discharged from hospital can be overwhelmed when they suddenly have to manage new conditions or medications. These changes can be particularly difficult for people on many medications or with multiple health…
- Trial name
- NCT02888782
- Testing
- Pharmacist Consultation
- Where
- 2 sites in Canada
- Volunteers
- 89 people
- Sponsor
- Memorial University of Newfoundland
Congestive Heart Failure, Medication Adherence
Assay to Measure Beta Blocker Adherence
This study will assess the feasibility and efficacy of using serum assay developed by Quest Diagnostics to detect the presence of beta blockers, specifically carvedilol and metoprolol succinate, in patients with heart failure.
- Trial name
- NCT05251974
- Testing
- Quest beta blocker assay
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Summa Health System
Meconium Ileus
Impact of Visceral Osteopathic Treatment on Meconium Evacuation in Preterm Infants
Timing of the first and last meconium stool is critical for oral feeding tolerance and proper gastrointestinal function. The time until premature infants pass their first meconium ranges from 1 hour to 27 days (median: 43 hours).
- Trial name
- NCT02140710
- Testing
- Osteopathic treatment
- Where
- Austria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Out-of-Hospital Cardiac Arrest
Implementation of Gold Standard EMS CPR Programs for 2% Improvement in Survival Rates of Out-of-Hospital Cardiac Arrest in a Metropolitan City
This study aims to improve the survival rate of out-of-hospital cardiac arrest patients by 2% through a bundle of three intervention measures including: 1) dispatcher-assisted CPR, 2) multi-tiered response team CPR, and 3)…
- Trial name
- 2% Project (NCT02540629)
- Testing
- Bundled EMS CPR approach including dispatcher-assisted CPR, 3-person team CPR, and feedback CPR monitoring device
- Where
- South Korea
- Volunteers
- 12,670 people
- Sponsor
- Seoul National University Hospital
Effectiveness
A Study on the Efficacy and Safety of Telitacicept in the Treatment of Children Ocular Myasthenia Gravis
Under conventional treatment regimens, pediatric ocular myasthenia gravis (OMG) is prone to relapse and is associated with corticosteroid-related adverse effects, indicating an unmet clinical need.
- Trial name
- NCT07298928
- Testing
- Telitacicept
- Where
- 3 sites in China
- Volunteers
- 30 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Prescriptions, Elderly (people Aged 65 or More)
Inappropriate Prescribing in the Elderly
The management of pharmacotherapy in elderly patients is an increasingly critical aspect, as polypharmacy, combined with the pharmacokinetic and pharmacodynamic changes typical of aging, makes older adults more sensitive to the…
- Conditions
- Prescriptions, Elderly (people Aged 65 or More), Hospitalized, Prevalence
- Trial name
- STOPP&START (NCT06760728)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Medication and Supplement Use During Pregnancy
Retrospective Analysis of Hospital Medical Records on Medication and Supplement Use in Pregnant Women
Monocentric study in University Hospitals Leuven (campus Gasthuisberg). Hospital medical records from all pregnant women who delivered between 01/07/2015 and 31/12/2015 in University Hospitals will be analyzed for the presence of…
- Trial name
- NCT02842216
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Alcohol Consumption, Psychoactive Substance Use
AlcoTail - Implementation of Tailored Interventions
This study aims to investigate the implementation and real-world effects of an intervention for harmful use of alcohol and psychoactive medicinal drugs among hospital inpatients.
- Trial name
- NCT04957628
- Testing
- Harmful alcohol use treatment, Non-prescribed psychoactive medicinal use treatment
- Where
- Norway
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
COVID-19
The Use of Chinese Herbal Medicine and Vitamin C by Hospital Care Workers in HK to Prevent COVID-19
This is a prospective randomized controlled trial study to explore whether the combination of Chinese herbal medicine and Vitamin C is effective and safe to prevent COVID-19 transmission among health care workers in Hong Kong…
- Trial name
- CHM-Cov-19-RCT (NCT05360004)
- Testing
- Chinese herbal medicine
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Patients With Multi Drug Resistant Gram-negative Bacteria, Colistin Resistance in Bacteria
Phenotypic and Genotypic Detection of Colistin Resistance
Evaluation of the disk elution test as reliable routine method for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution.
- Trial name
- NCT07487116
- Testing
- disk elution test
- Volunteers
- 90 people
- Sponsor
- Assiut University
Other Conditions That May Be A Focus of Clinical Attention
Effectiveness of Buddhist Intergrated Group Intervention on Minefulness in Adolescents
The pupose of the study is to determine the effectiveness of the Buddhist integrated group intervention improve the mindfulness in adolescents by a randomized controlled trial.The study divede the adolescents in two groups group…
- Trial name
- NCT01605604
- Testing
- buddhist mind fullness
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pulmonary Medicine, Ventilators, Mechanical
Comparison of Thoracic Vibration With Classical Respiratory Physiotherapy in Patients With Mechanical Ventilation
Inclusion and Exclusion Criteria: Patients aged 18-65 years who are admitted to the investigator's 3rd Stage Intensive Care Unit and are dependent on mechanical ventilation will be included.
- Trial name
- NCT04731532
- Testing
- classical respiratory physiotherapy with thoracic vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Drug Resistance, Bacterial, Carbapenems
Wastewater Surveillance for Carbapenem-Resistant Organism Outbreak Prediction in a Chinese Tertiary Hospital
Carbapenem-resistant organisms (CRO) pose a critical threat to global public health, and hospitals serve as major epicenters for their emergence and spread.
- Conditions
- Drug Resistance, Bacterial, Carbapenems, Wastewater
- Trial name
- WW-CRO-PREDICT (NCT07804433)
- Where
- China
- Volunteers
- 720 people
- Sponsor
- Peking Union Medical College Hospital
Overweight/Obesity, Prediabetes
Mobile Internet Healthcare and Three Disciplines Co-management Intervention for Overweight/Obese Prediabetic Patients
Diabetes mellitus is a chronic metabolic disease associated with a high rate of disability and mortality. Prediabetes is the intermediate stage from normal blood glucose to diabetes.
- Conditions
- Overweight/Obesity, Prediabetes, Weight Management
- Trial name
- NCT06147752
- Testing
- mobile internet healthcare and "co-management of three disciplines"
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Heart Failure
Medication Adherence Telemonitoring to Reduce Heart Failure Readmissions
The overall purpose of this project is to determine the feasibility of conducting a large scale randomized clinical trial that compares remote monitoring of adherence to loop diuretics using a wireless electronic pillcap with…
- Trial name
- TEAM-HF (NCT02378571)
- Testing
- Medication adherence telemonitoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Medication Reconciliation
Implementation and Evaluation of a Medical Reconciliation Protocol at Brigham and Women's Hospital
An incomplete understanding of patients' preadmission medications and failure to reconcile these with medications ordered in the hospital and at discharge are major, previously unappreciated, causes of adverse drug events (ADEs).
- Trial name
- NCT00296426
- Testing
- New technology - PAML
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- Brigham and Women's Hospital
Drug Resistant Tuberculosis
Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment
The goal of the BringBPaL2Me Trial, a multi-principal investigator, multi-site, cluster randomized, non-inferiority trial is to compare nurse-led RR-TB treatment in primary care clinics to standard of care physician-led RR-TB…
- Trial name
- NCT05671718
- Testing
- Nurse-Led Treatment in Primary Care
- Where
- 5 sites in South Africa
- Volunteers
- 2,944 people
- Sponsor
- Johns Hopkins University
Depressive Disorder, Major
Effectiveness of Cariprazine Monotherapy for Treatment of Major Depressive Disorder
This trial protocol aims to evaluate the effectiveness and safety of cariprazine monotherapy compared to treatment as usual for major depressive disorder (MDD) in a pragmatic open-label randomized controlled trial (RCT) conducted…
- Trial name
- NCT05933538
- Testing
- Cariprazine, Treatment as usual
- Volunteers
- 110 people
- Sponsor
- Sultan Qaboos University