Clinical trials: Hospital Medicine
Out-of-Hospital Cardiac Arrest
AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on…
- Trial name
- NCT03191240
- Testing
- Vasopressins, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Carcinoma, Non-Small-Cell Lung, Cancer of the Gastrointestinal Tract
Effect of Qigong Therapy in Patients With Advanced Lung and Gastrointestinal Cancer Undergoing Chemotherapy
Cancer patients face a number of symptoms related to treatment or disease which may impair quality of life, such as decreased functional capacity, fatigue, nausea an vomiting, distress, depression and unmet psychological needs.
- Trial name
- NCT01374100
- Testing
- Standard Exercise, Qigong Exercise
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- McGill University
Adverse Drug Reaction
Adverse Drug Reactions With Fatal Outcome
The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015
- Trial name
- NCT02838212
- Testing
- adverse drug reaction
- Volunteers
- 1,135 people
- Sponsor
- Germans Trias i Pujol Hospital
Drug Resistance, Bacterial
Epidemiology of Antimicrobial-use and Antimicrobial-resistant Infections in Four Hospitals in Thailand
The main goal of this retrospective observational study is to understand how stepping down antibiotic treatment (called antibiotic de-escalation) affects patients who receive it compared to those who don't after received a…
- Conditions
- Drug Resistance, Bacterial, Bacteremia
- Trial name
- NCT07082465
- Where
- 4 sites in Thailand
- Volunteers
- 108,000 people
- Sponsor
- University of Oxford
Admitted Multimorbid Patients
Implementation of Pharmacogenetic Testing in Hospital Wards
The purpose of this study is to investigate whether it is feasible to implement pharmacogenetic testing as part of medication review while the patient is admitted to hospital.
- Trial name
- FAGLIS (NCT04573491)
- Testing
- Pharmacogenetic test, Medication review
- Where
- Norway
- Volunteers
- 46 people
- Sponsor
- Hospital Pharmacy Enterprise, South Eastern Norway
Atrial Fibrillation
Alster Man and Machine: Comparison of Manual and Mechanical Remote Robotic Catheter Ablation for Drug-Refractory Atrial Fibrillation
Long term results after pulmonary vein isolation (PVI) with robotic navigation in patients with drug refractory atrial fibrillation are not inferior to manual radiofrequency current ablation.
- Trial name
- NCT00982475
- Testing
- Pulmonary vein isolation with radiofrequency current
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Dr. Kai Jaquet
Patients With Bronchopulmonary Cancer
Impact of Hospital Pharmacist on Drug Management in Patients With Bronchopulmonary Cancer
This is a prospective, non-interventional study to evaluate impact of hospital pharmacist on drug management in patients (only questionnaires) with bronchopulmonary cancer treated by Chemotherapy and/or Immunotherapy or Oral…
- Trial name
- IMPACTO (NCT06469957)
- Testing
- Questionnaires and data collection sheet
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Cystic Fibrosis
Study of Satisfaction of Patients and Care Providers for an Alternate Follow-up With In-hospital Consults and Tele-consult for Patients With Cystic Fibrosis
The pandemic forced us to develop home follow-up for patients with chronical diseases . In the same time, the new era of treatment for cystic fibrosis considerably improves the health of patients with this pathology.
- Trial name
- FollowMuco (NCT05249322)
- Testing
- Follow-up alternating between face-to-face consultation and teleconsultation every three months.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Major Depressive Disorder
Transcranial Laser Therapy for Major Depressive Disorder
The purpose of this study is to see if using Transcranial LED Therapy (TLT) using the PhotoMedex's Omnilux NEw-U LED helps improve symptoms of major depressive disorder (MDD).
- Trial name
- ELATED (NCT01538199)
- Testing
- Near-infrared radiation via Transcranial LED Therapy
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Paolo Cassano
Anti-Bacterial Agents
Carbapenems De-escalation as Antimicrobial Stewardship
Early de-escalation of carbapenems can reduce unnecessary use of carbaepenems compared with late de-escalation without compromised clinical outcomes
- Trial name
- NCT03114358
- Testing
- Early Carbapenem de-escalation
- Volunteers
- 104 people
- Sponsor
- Chiang Mai University
Acute Stroke
Effectiveness of a Public Campaign to Increase Stroke Awareness in Reducing Prehospital Delay
The starting hypothesis is that a multilevel educational campaign, specifically developed for the local community, can increase public stroke awareness and reduce pre-hospital delay.
- Trial name
- NCT01881152
- Testing
- Educational campaign, Usual care
- Where
- 5 sites in Italy
- Volunteers
- 1,772 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Malnutrition, Anorexia
Sativex® and Gentamicin for Optimized Pharmagological Treatment in Older Patients (CanPan)
Malnutrition and inappropriate prescribing of renally excreted drugs are common among older persons and are associated with severe consequences such as complicated courses of treatment, mortality, and reduced quality of life.
- Conditions
- Malnutrition, Anorexia, Cannabis, Aging
- Trial name
- CanPan (NCT05503147)
- Testing
- Sativex
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Ove Andersen
Medication Reconciliation
Medication Reconciliation for Patients Over 65 Years Old : Cost Analysis of the Process Implemented in the Polyvalent Internal Medical Unit of Rennes University Hospital
Among the strategies to secure the patient's care path, medication reconciliation is a powerful approach for the prevention and interception of medication errors.
- Trial name
- CONTEMPS (NCT03670433)
- Testing
- Cost analysis of medication reconciliation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Rennes University Hospital
Cancer
Health Course of Patients Undergoing Per os Anti-cancer Therapy.
During the last few years, the medical care of oncohematologic cancers diagnosed patients was shaken by the arrival of new therapies : targeted therapies.
- Trial name
- MinOS (NCT03454971)
- Testing
- MinOS protocol
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Groupe Hospitalier Mutualiste de Grenoble
Patient Monitoring
Continuous Wireless Monitoring in Internal Medicine Unit: the Green Line From Hospital to Territory
Study Information Indication* This is a prospective, randomized, controlled, open-label, monocentric study for the evaluation of two different settings of critically ill patients recovered in Internal Medicine unit (IMU) and…
- Trial name
- GreenLightHT (NCT03764709)
- Testing
- Vital signs wireless monitoring system
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Socio Sanitaria Territoriale del Garda
Metastatic Renal Cell Carcinoma
Impact of the PRISM-care Multidisciplinary Oncology Program on Secured Drug Intake of Patients With Kidney Cancer
The rise of oral targeted therapies favors outpatient care of cancer patients but exposes them to new risks compared to the injectable chemotherapy in the hospital: non-adherence to treatment, inappropriate management of side…
- Trial name
- PRISM care (NCT02849535)
- Testing
- PRISM care program
- Where
- 12 sites in France
- Volunteers
- 190 people
- Sponsor
- Hospices Civils de Lyon
Ursodeoxycholic Acid, Primary Biliary Cirrhosis
Development of Ursodeoxycholic Acid 300 mg at Hospital Das Clinicas of the University of São Paulo School of Medicine
A manipulation and an integral part of the pharmaceutical practice, where, in addition to the supply of medicines and personalized products, they represent an alternative to the therapeutic schemes, manipulating drugs of almost…
- Trial name
- NCT03489889
- Testing
- Ursodeoxycholic Acid 300mg tablet, Ursodeoxycholic Acid 300mg capsule
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Coronary Syndrome
A Pharmacist-Led Hospital-Based Intervention to Support Medication Adherence Following Acute Coronary Syndrome
Background Medication adherence following acute coronary syndrome (ACS) is often sub-optimal and is associated with poor clinical outcomes.
- Trial name
- NCT03218813
- Testing
- Intervention cohort ('after' group)
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- King's College London
Salivary Gland Carcinoma, Precision Therapy
Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing
Patients with salivary gland carcinoma were divided into groups according to HER2, NTRK, AR, TROP-2, etc. Patients in different groups were given precision targeted therapy or chemotherapy to evaluate the efficacy (ORR rate) and…
- Trial name
- NCT06145308
- Testing
- Cohort 1 (HER2-positive, RC48-ADC), Cohort 2 (NTRK-fusion or NTRK-mutant), Cohort 3 (AR-positive, leuprolide + bicalutamide + abiraterone)
- Where
- 2 sites in China
- Volunteers
- 39 people
- Sponsor
- Peking Union Medical College
Suicide Prevention
Safer Still (Exploratory Project 3)
The long-term goal is to decrease suicide and suicidal behaviors in at-risk youth through preventative interventions. Investigators propose to develop an interactive intervention ("Safer Still") to help promote safe storage of…
- Trial name
- NCT06558409
- Testing
- " Safer Still " Interactive Intervention, Enhanced Usual Care (EUC):
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Jeff Bridge