Clinical trials: Hospitalization, open to volunteers
Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic)
Comparing Glycemic Outcomes of Carbohydrate Counting vs. Fixed Mealtime Insulin Dosing in Hospitalized Patients With Hyperglycemia
The study compares two current practices for calculating insulin dose for admitted patients: flexible fixed mealtime dosing based on percent of meal eaten and carbohydrate counting based on amount of carbohydrates eaten.
- Conditions
- Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic), Hyperglycemia Due to Type 2 Diabetes Mellitus
- Trial name
- MEND (NCT07808398)
- Testing
- Carbohydrate-counting-based prandial rapid-acting insulin dosing, Flexible fixed mealtime rapid-acting insulin dosing based on percentage of meal consumed
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Eating Disorders
Developing Recommendations to Support Therapeutic Alliance in Eating Disorders Inpatient Treatment
The ALLIANCE study aims to understand and improve treatment relationships between staff and service users in inpatient eating disorder settings.
- Trial name
- ALLIANCE (NCT06961032)
- Where
- 3 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Social Needs, Health-Related Social Needs
The Social Needs Assistance for Hospitalized Kids Trial
The goal of this clinical trial is to determine the best way to help families access social and economic support services in order to improve children's health for hospitalized children and their families/caregivers.
- Conditions
- Social Needs, Health-Related Social Needs, Social Determinants of Health (SDOH), Social Needs Status
- Trial name
- SNAK (NCT07687238)
- Testing
- Active Assistance by Navigators, Passive Referral
- Where
- 6 sites in United States
- Volunteers
- 1,880 people
- Sponsor
- University of California, San Francisco
Schizophrenia
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia
The primary objective for this study is to evaluate the efficacy of NBI-1117570 compared with placebo on improving behavioral and psychological symptoms of schizophrenia in adults who warrant inpatient hospitalization.
- Trial name
- NCT07288333
- Testing
- NBI-1117570
- Where
- 6 sites in Bulgaria, Romania and 1 more
- Volunteers
- 120 people
- Sponsor
- Neurocrine Biosciences
Anticoagulants; Circulating, Hemorrhagic Disorder
MEdication Counselling Models for Outpatient oRal antIcoaguLation
The goal of this clinical trial is to investigate whether telepharmacy-led counselling can improve medication adherence, knowledge, and hospitalisation/mortality compared with pharmacist-led counselling in adult outpatients…
- Trial name
- MEMORIAL (NCT06290440)
- Testing
- Telepharmacy-led counselling, Pharmacist-led counselling
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Heart Failure
Gender Specific Registry in Subjects Hospitalized With Heart Failure in Santiago
This is an observational registry, which main purpose is to assess sex-related differences in heart failure (HF) presentation, management, and prognosis in patients admitted to a hospital with a certain diagnosis of HF.
- Trial name
- GENESIS (NCT05960968)
- Where
- Chile
- Volunteers
- 500 people
- Sponsor
- Fundacion de la Sociedad Chilena de Cardiologia y Cirugia Cardiovascular
Periprosthetic Knee Infection
Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Knee Infection: a Microdialysis Study
This study aims to use the technique of microdialysis to analyse the intraarticular space of the knee joint after removal of a periprosthetic joint infection affected endoprosthesis and implantation of an antibiotic-containing…
- Trial name
- PJI_K_MD (NCT07299565)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Community-acquired Pneumonia, Urinary Tract Infections
Physical Rehabilitation of Older Persons Following a Community-Acquired Infection Hospitalization - A Randomised-Controlled Trial
Community-acquired infections such as community-acquired pneumonia (CAP) and urinary tract infection (UTI) remain leading causes of hospitalization and death due to infections in older persons in Europe.
- Trial name
- REHAB-CAI (NCT06689280)
- Testing
- Video-supervised home-based exercise training
- Where
- 3 sites in Denmark
- Volunteers
- 460 people
- Sponsor
- Nordsjaellands Hospital
Risk of Malnutrition
Plant-based Versus Animal-based Oral Nutritional Supplements
Background information: Many people who are admitted to the hospital are at risk of malnutrition. In some patient groups, this can be as high as 40%.
- Trial name
- PAVOS (NCT07399886)
- Testing
- Fresubin Plant-based drink vanilla©, Fresubin Yodrink raspberry©
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Neutropenic Fever
Antibiotic Stewardship in Suspected Neutropenic Fever (ASTERIC Trial)
Executive Summary Background: Neutropenic Fever (NF), or febrile neutropenia, occurs in patients with early stage and metastatic solid tumours, non-leukaemic haematological cancers and acute leukaemia.
- Trial name
- NCT06794320
- Testing
- NF Protocol, ASTERIC protocol
- Where
- Hong Kong
- Volunteers
- 648 people
- Sponsor
- The University of Hong Kong
Sepsis
Call for Life Sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-attributable mortality in sub-Saharan Africa (sSA) is high, with in-hospital mortality in some settings approaching 40%.
- Trial name
- C4L-Sepsis (NCT07407868)
- Testing
- Interactive Voice Response system-Call for life IVR
- Where
- 2 sites in Uganda
- Volunteers
- 1,410 people
- Sponsor
- Makerere University
Depression - Major Depressive Disorder, Depressive Episodes
TDM-Guided Treatment With SSRIs in Hospitalized Adults and Children
Depression in childhood and adolescence is a serious and increasing public-health problem associated with profound short- and long-term consequences, including impaired social and educational functioning, increased risk of…
- Trial name
- NCT07478796
- Testing
- Fluoxetine, Escitalopram, Sertralin
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Poznan University of Medical Sciences
Cardiogenic Shock
The Clinical and Hemodynamic Course of Cardiogenic Shocks Hospitalized in Critical Care
Cardiogenic shock is a frequent reason for hospitalization in critical care units, with high mortality (50%). Several French registries have been created to improve knowledge of the prognostic factors of cardiogenic shock.
- Trial name
- HEMOCARD (NCT05752383)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Borderline Personality Disorder
Pilot Study on Auricular Acupuncture in Hospitalized Adults With Borderline Personality Disorder
The goal of this pilot study is to evaluate the feasibility and preliminary effectiveness of a brief auricular acupuncture program delivered by mental health nurses as a complementary therapy for adults hospitalized with…
- Trial name
- ACUPSY (NCT07476300)
- Testing
- Auricular acupuncture program based on the N.A.D.A. protocol
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Jenny Gentizon
Cancer
Feasibility Study of a Transition Pathway at Discharge From Full Hospitalization in Oncology
Patient reported outcomes (PRO) measure the health status directly reported by the patients, without external interpretation, generally collected using self-questionnaires, including online tools (ePRO).
- Trial name
- PATROL (NCT07256444)
- Testing
- OncoCare transition program
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Trauma Injury, Depression
Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries
Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer…
- Conditions
- Trauma Injury, Depression, Anxiety, Anger
- Trial name
- NCT06812247
- Testing
- Therapy dog visits, Dog handler visits
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Boston Medical Center
Acute Kidney Injury
A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial
The COPE-AKI study is a randomized, pragmatic, parallel-arm trial comparing a multimodal intervention to usual care on hospital-free days through 90 days of study follow up.
- Trial name
- COPE-AKI (NCT05805709)
- Testing
- Study Physician/Advance Practice Provider, Nurse Navigator, Pharmacist
- Where
- 9 sites in United States
- Volunteers
- 2,145 people
- Sponsor
- University of Pittsburgh
Aging, Hospitalization
Personalized Exercises Program Prescription to Prevent Functional Decline Throughout Older Adults Hospitalization
Bed rest related to hospitalization contributes to the physical decline in capacities of the elderly, the loss of autonomy accelerated in post-hospitalization and the prevalence of the iatrogenic functional decline is about 20 to…
- Trial name
- NCT04078334
- Testing
- MATCH, PATH, PATH 2.0
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Université du Québec a Montréal
Nursing Home Care, Hospitalisation Prevention
Mobile Geriatric Unit (MGU) to Reduce Hospitalisations in Nursing Home Residents
This prospective observational before-after study evaluates the impact of a Mobile Geriatric Unit (MGU) on hospitalisation rates among nursing home residents.
- Trial name
- MGU (NCT07634757)
- Testing
- Mobile Geriatric Unit (MGU)
- Where
- Germany
- Volunteers
- 4,907 people
- Sponsor
- Universität des Saarlandes
Atrial Functional, Mitral Regurgitation (MR)
PRECISE-AFMR I: Transcatheter Mitral Valve Edge-to-Edge Repair for Atrial Functional Mitral Regurgitation in Patients at High Surgical Risk
Atrial functional mitral regurgitation (AFMR) develops when enlargement and remodeling of the left atrium and mitral annulus prevent the mitral valve leaflets from closing completely, allowing blood to leak backward through the…
- Trial name
- PRECISE-AFMR I (NCT07741253)
- Testing
- Transcatheter Edge-to-Edge Repair
- Where
- China
- Volunteers
- 182 people
- Sponsor
- China National Center for Cardiovascular Diseases