Clinical trials: Hospitalized
COVID-19 Disease
Study of LAU-7b for the Treatment of Coronavirus Disease 2019 (COVID-19) Disease in Adults
A randomized, double-blind, placebo-controlled Phase 2/3 Study of LAU-7b against confirmed COVID-19 Disease in hospitalized patients at a higher risk of complications.
- Trial name
- RESOLUTION (NCT04417257)
- Testing
- LAU-7b
- Where
- 29 sites in United States, Canada
- Volunteers
- 351 people
- Sponsor
- Laurent Pharmaceuticals Inc.
Dementia, Acute Medical Event
Implementation of Function Focused Care in Acute Care
Older adults with Alzheimer's Disease and Related Dementias (ADRD) comprise approximately 25% of hospitalized older adults. These individuals are at increased risk for functional decline, delirium, falls, behavioral symptoms…
- Conditions
- Dementia, Acute Medical Event, Hospitalization
- Trial name
- NCT04235374
- Testing
- FFC-AC-EIT
- Where
- 14 sites in United States
- Volunteers
- 455 people
- Sponsor
- University of Maryland, Baltimore
COVID-19
Study of Niclosamide in Moderate and Severe Hospitalized Coronavirus-19 (COVID-19) Patients
Study of ANA001 in Moderate and Severe COVID-19 Patients
- Trial name
- NCT04603924
- Testing
- Niclosamide
- Where
- 8 sites in United States
- Volunteers
- 49 people
- Sponsor
- NeuroBo Pharmaceuticals Inc.
Covid-19
Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19
The overall objective of this study is to evaluate the clinical efficacy of oral famotidine in symptomatic non-hospitalized patients with confirmed COVID-19.
- Trial name
- NCT04724720
- Testing
- Famotidine
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Northwell Health
COVID-19
Non-comparative Trial of the Combination of HCQ and AZI in the Treatment of ICU Patients
This research is designed as an open-label,non-comparative prospective trial.
- Trial name
- NCT04458948
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of New Mexico
COVID-19
LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
This study looks at the safety and effectiveness of LY3819253 in treating COVID-19 in people who have been hospitalized with the infection.
- Trial name
- NCT05780268
- Testing
- LY3819253, Remdesivir
- Where
- 57 sites in United States, Denmark and 2 more
- Volunteers
- 314 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Opioid Dependence, Chronic Pain
Feasibility and Preliminary Efficacy of an Opioid Stewardship Program in Hospitalized Patients With Chronic Pain
This study aims to investigate the feasibility and preliminary efficacy of an enhanced opioid stewardship program, tailored to the needs of hospitalized patients with chronic pain with opioid dependence, incorporating real-time…
- Trial name
- NCT05370326
- Testing
- Enhanced Opioid Stewardship Program
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Yale University
Pneumonia
Reducing Length of Stay for Veterans Hospitalized With Pneumonia
This is a pilot study to implement a computer based intervention to safely reduce length of hospital stay and time to conversion to oral antibiotics for patients with pneumonia.
- Trial name
- NCT01068548
- Testing
- reminder
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- VA Office of Research and Development
Hyponatremia
Maintenance Intravenous Fluids in Children
Hyponatraemia arises in between 20% and 45% of sick hospitalized children. An important reason for this high incidence could be use of hypotonic fluids in sick children for maintenance fluid therapy.
- Trial name
- NCT00621348
- Testing
- Isotonic fluid, Hypotonic fluid
- Where
- India
- Volunteers
- 167 people
- Sponsor
- All India Institute of Medical Sciences
Influenza A
Study of Efficacy and Safety of IV VIS410 Plus Oseltamivir Versus Oseltamivir in Hospitalized Adults With Influenza A
This study is to compare the efficacy and safety of VIS410 in combination with oseltamivir vs oseltamivir alone in severely ill subjects with influenza A infection requiring oxygen support.
- Trial name
- NCT03040141
- Testing
- Low dose of VIS410, High dose of VIS410
- Where
- 114 sites in United States, Australia and 18 more
- Volunteers
- 89 people
- Sponsor
- Visterra, Inc.
Diabetes Mellitus
Continuous Glucose Monitoring in Hospitalized Patients With Diabetes Mellitus
The purpose of this study is to determine if patient's own Continuous Glucose Monitor (CGMs) worn in the non-ICU hospital setting have adequate accuracy for blood glucose monitoring when compared to point-of-care (POC) capillary…
- Trial name
- NCT04653454
- Testing
- Continuous Glucose Monitor (CGM)
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Mayo Clinic
Hyponatremia
Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia
Hyponatremia is a condition in which there is a low sodium level in the blood. Individuals with cirrhosis may develop low blood sodium as a complication of their liver disease.
- Trial name
- NCT01890694
- Testing
- Tolvaptan, Hepatic Encephalopathy Assessment, Quality of Life Assessment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- NYU Langone Health
Urinary Tract Infection, Infection Due to ESBL Bacteria
Extended Spectrum Betalactamase Producing Bacteria; Epidemiology and Treatment in Non-hospitalized Patients
This project aims at investigating the duration of human fecal carriage of bacteria harboring plasmid-borne resistance genes expressing Extended Spectrum beta-lactamases (ESBL), risk factors for infections with such bacteria and…
- Conditions
- Urinary Tract Infection, Infection Due to ESBL Bacteria, Environmental Contamination of ESBL
- Trial name
- ESCAPE (NCT01838213)
- Volunteers
- 760 people
- Sponsor
- Vestre Viken Hospital Trust
Focus: Hospitalized Patients
Hospital to Home Outcomes
Home Nurse Visit post discharge.
- Trial name
- NCT02081846
- Testing
- Nurse Home Visit, Standard of Care
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Psychotic Disorders
Acceptance and Commitment Therapy for the Inpatient Treatment of Psychosis
There is a substantial need for enhancing the efficacy and effectiveness of Veterans Health Administration (VHA) inpatient services for psychosis and tailoring them to support recovery.
- Trial name
- ACT-IP (NCT01981356)
- Testing
- Acceptance and Commitment Therapy, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Patient Readmission, Adverse Drug Event
Regional Data Exchange to Improve Care for Veterans After Non-VA Hospitalization
Among older VA patients who have Medicare coverage, 43% use both VA and non-VA (Medicare-covered) services. VA and non-VA providers are often uninformed about encounters, treatments and test results provided in the other system.
- Conditions
- Patient Readmission, Adverse Drug Event, Cost
- Trial name
- NCT02689076
- Testing
- HIE Notification, Care transitions intervention
- Where
- 2 sites in United States
- Volunteers
- 796 people
- Sponsor
- VA Office of Research and Development
Covid19
ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19
This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure.
- Trial name
- TESICO (NCT04843761)
- Testing
- Remdesivir, Aviptadil, Corticosteroid
- Where
- 40 sites in United States
- Volunteers
- 473 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Study to Evaluate the Safety, Tolerability, and Efficacy of BGE-175 in Hospitalized Adults With Coronavirus Disease 2019 (COVID-19) That Are Not in Respiratory Failure
The primary objectives of this study are to evaluate the safety, tolerability, and efficacy of BGE-175 in participants ≥ 50 years of age hospitalized with documented COVID-19.
- Trial name
- NCT04705597
- Testing
- BGE-175
- Where
- 26 sites in United States, Argentina and 1 more
- Volunteers
- 194 people
- Sponsor
- BioAge Labs, Inc.
Heart Failure
Integrated Tele-monitoring and Patient-centric Health Coaching Strategy in Patients Hospitalized With Heart Failure
This study evaluates the effectiveness of remote tele-monitoring and health coaching in helping to reduce hospitalizations in heart failure patients.
- Trial name
- Tele-HC (NCT02391987)
- Testing
- Tele-monitoring and health coaching
- Where
- 5 sites in United States
- Volunteers
- 112 people
- Sponsor
- Mayo Clinic
Hospitalization, Child Health
Comparative Effectiveness of Direct Admission & Admission Through Emergency Departments for Children
At a national level, emergency departments (EDs) serve as the portal of hospital admission for 75% of hospitalized children. The remainder occur via direct admission, defined as admission to hospital without first receiving care…
- Trial name
- NCT04192799
- Testing
- Direct admission, ED admission
- Where
- 3 sites in United States
- Volunteers
- 1,997 people
- Sponsor
- Dartmouth-Hitchcock Medical Center