Clinical trials: Hospitalized COVID-19
Critical Illness
Modified Pediatric Early Warning Score and Modified PRISA II During COVID-19 Pandemic
One of the most important factors in pediatric emergency units is the correct decision of the patient inpatient or outpatient treatment. If the disease progresses critically, the decision of hospitalization comes to the fore.
- Trial name
- NCT04876872
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 894 people
- Sponsor
- Karadeniz Technical University
Pulmonary Embolism, Covid-19
Prevalence and Characteristics of Pulmonary Embolism on COVID-19 Patients Presenting Respiratory Symptoms
Multicentric case-control study that is aims at: evaluating the prevalence of pulmonary embolism among a large population of consecutive patients admitted for COVID-19 pneumonia into two large university hospitals in Paris…
- Trial name
- COVID-EP (NCT04420312)
- Where
- France
- Volunteers
- 1,024 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Patients Hospitalized in the Hospices Civils of Lyon, COVID-19 Disease
Measurement of the Efficacy of MORPHINE in the Early Management of Dyspnea in COVID-19 Positive Patients
Morphine is used in the treatment of dyspnea and polypnea with a proven benefit on the improvement of these symptoms, both etiologically and symptomatically.
- Conditions
- Patients Hospitalized in the Hospices Civils of Lyon, COVID-19 Disease, Moderate to Severe Dyspnea, Without Resuscitation Objective Management
- Trial name
- CODYS (NCT04522037)
- Testing
- No intervention / Compare the difference in respiratory rate between H0 and H12 of the initiation of morphine between the control and interventional groups
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury, Covid19
Renal Involvement in Hospitalized Children With COVID-19
Covid-19 is an important human and animal pathogen, it mostly causes respiratory and gastrointestinal symptoms. Clinical features range from a common cold to severe diseases such as severe acute respiratory distress syndrome…
- Conditions
- Acute Kidney Injury, Covid19, Renal Dysfunction, Coronavirus Infection
- Trial name
- RIHCC (NCT04788394)
- Testing
- data review, data comparing
- Where
- Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
SARS-CoV Infection, Covid19
KIDney Injury in Times of COVID-19 (KIDCOV)
There is an unmet need to evaluate the impact of sub-clinical/mild COVID19 disease in the outpatient setting on prevalent and incident renal injury, as this data is currently unavailable.
- Conditions
- SARS-CoV Infection, Covid19, Corona Virus Infection, Acute Kidney Injury
- Trial name
- KIDCOV (NCT04705766)
- Testing
- Urine Collection
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Covid19
Efficacy and Safety of Two Hyperimmune Equine Anti Sars-CoV-2 Serum in COVID-19 Patients
Reports of the use of plasma from convalescent patients and purified immunoglobulin preparations in respiratory infections by various viral agents and SARS-CoV-2 in severely ill patients suggest that specific neutralizing…
- Trial name
- SECR-01 (NCT04610502)
- Testing
- Administration of Equine immunoglobulin anti SARS-CoV-2
- Where
- 4 sites in Costa Rica
- Volunteers
- 26 people
- Sponsor
- Caja Costarricense de Seguro Social
Covid-19
Study to Evaluate STI-1499 (COVI-GUARD) in Patients With Moderate COVID-19
Randomized, placebo-controlled study to evaluate the safety, pharmacokinetics and efficacy of a single dose of STI-1499 (COVI-GUARD™) in hospitalized patients with moderate COVID-19
- Trial name
- NCT04454398
- Testing
- COVI-GUARD, Standard of Care
- Sponsor
- Sorrento Therapeutics, Inc.
COVID-19
#StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19
BACKGROUND Despite drastic quarantine measures, COVID-19 continues to propagate and threatens global healthcare systems by saturating their capacity with high transmissibility and the particularly protracted length of stay needed…
- Trial name
- #StayHome (NCT04385264)
- Testing
- Hydroxychloroquine, Mannitol
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Pneumonia, COVID-19
A Study to Evaluate Efficacy and Safety of PTC299 (Emvododstat) in Hospitalized Participants With Coronavirus (COVID-19)
This is a randomized, double-blind, placebo-controlled, multicenter, 28-day study of adult participants hospitalized with COVID-19, with a safety follow-up telephone call at Day 60.
- Conditions
- Pneumonia, COVID-19, Coronavirus
- Trial name
- FITE19 (NCT04439071)
- Testing
- PTC299, SOC
- Where
- 41 sites in United States, Australia and 9 more
- Volunteers
- 189 people
- Sponsor
- PTC Therapeutics
Covid19
Study of ZnAg Liquid Solution to Treat COVID-19 Symptomatic Participants
This is a multi-site, randomized, double-blind, placebo-controlled study assessing the efficacy and safety of ZnAg liquid solution in symptomatic participants with acute COVID-19 that are not hospitalized at the time of…
- Trial name
- NCT04610138
- Testing
- CNM-ZnAg
- Where
- 5 sites in Brazil
- Volunteers
- 296 people
- Sponsor
- Clene Nanomedicine
COVID-19
Impact of COVID-19 Outbreak on Non-COVID-19 Patients
The Geneva Canton organized the health crisis of the COVID-19 epidemic around the care of COVID patients at the University Hospital (HUG), by moving the care of non-COVID patients to private hospitals of the canton.
- Trial name
- NoCOVImpact (NCT04537559)
- Where
- Switzerland
- Volunteers
- 240,000 people
- Sponsor
- University Hospital, Geneva
COVID-19 Pneumonia
A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia
This study (EMPACTA) will a) evaluate the efficacy and safety of tocilizumab (TCZ) compared with a placebo in combination with standard of care (SOC) in hospitalized participants with COVID-19 pneumonia, and b) include an…
- Trial name
- EMPACTA (NCT04372186)
- Testing
- Tocilizumab
- Where
- 44 sites in United States, Brazil and 4 more
- Volunteers
- 377 people
- Sponsor
- Genentech, Inc.
COVID-19
Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients
Given the current lack of an effective drug or therapy, a clinical trial to better understand the safety and efficacy of therapeutic plasma exchange (TPE) in COVID-19 patients is urgently needed.
- Trial name
- NCT04592705
- Testing
- Therapeutic plasma exchange
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Larkin Community Hospital
COVID-19 Pneumonia, COVID-19
Clinical, Virological, Serological and Immunological Characteristics During and Following COVID-19 Hospitalization
Assessment of the association between the severity of COVID-19 and SARS-CoV-2 NAb titers levels for up to six months following primary infection using a live virus NAb assay.
- Trial name
- COVISERA (NCT05274373)
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Nordsjaellands Hospital
Corona Virus Infection
A Phase 1b Trial to Evaluate Safety and Effect of SAR443122 on Immune System in Severe COVID-19
Primary Objective: To evaluate the effect of SAR443122 relative to the control arm on the hyperinflammatory state as measured by C-reactive protein (CRP) levels in adult patients hospitalized with severe coronavirus disease 2019…
- Trial name
- NCT04469621
- Testing
- SAR443122
- Where
- 10 sites in Argentina, Brazil and 3 more
- Volunteers
- 68 people
- Sponsor
- Sanofi
COVID-19
Administration of Anti-SARS-CoV-2 Convalescent Plasma in Hospitalized, Non-ICU Patients With COVID-19
The purpose of this study is to assess the efficacy and safety of the administration of anti-SARS-CoV-2 convalescent plasma in COVID-19 patients who are sick enough to warrant hospitalization, but not yet admitted to the ICU…
- Trial name
- NCT04467151
- Testing
- anti-SARS-CoV-2 plasma
- Sponsor
- Kashif Khan
Covid19
Assessing Safety, Hospitalization and Efficacy of rNAPc2 in COVID-19
Sequential randomized, multicenter, active comparator study to evaluate the hypothesis that rNAPc2 (AB201), a novel, potent and highly selective tissue factor inhibitor with anticoagulant, anti-inflammatory and potential…
- Trial name
- ASPEN (NCT04655586)
- Testing
- rNAPc2, Heparin
- Where
- 24 sites in United States, Argentina and 1 more
- Volunteers
- 160 people
- Sponsor
- ARCA Biopharma, Inc.
SARS-COV2, COVID19
Identifying Functional and Psycho-social Complaints After Hospitalization for SARS-CoV-2 Infection( COVID 19)- REPERCOV
Since December 2019, China and then the rest of the world have been affected by the rapid spread of a new coronavirus infection called SARS-CoV-2 (severe acute respiratory syndrome coronavirus), the clinical expression of which…
- Trial name
- REPERCOV (NCT04561154)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Centre Hospitalier le Mans
SARS-CoV2 Infection, Proximal Tubule Dysfunction
Analysis of SARS-CoV2 Urine Viral Particles and Association With Proximal Tubular Dysfunction
The primary goal is to detect Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV2) urine viral particles in patients in intensive care units, hospitalized for coronavirus Coronavirus Disease-19 (COVID-19) infection, and…
- Trial name
- CovUrinePTD (NCT04937712)
- Testing
- RT-PCR SARS-COV2 in urine
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Central Hospital, Nancy, France
Long-term Consequences of COVID-19 Infection
Postoperative Outcomes of Covid-19 Patients Who Were Hospitalized in a Training and Research Hospital, Who Were Operated on Electively
The Covid-19 infection has led to global health crisis. As the number of patients recovering from Covid-19 infection increases, it is necessary to create an understanding of the health problems that concern them.
- Trial name
- NCT05372341
- Testing
- descriptive
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Samsun University