Clinical trials: Hospitalized COVID-19
Covid19
Lung Ultrasound Implementation in the Management of Patients Hospitalized With COVID-19
Lung ultrasound (LUS) has also been shown to be more accurate than chest x-ray in identifying pulmonary consolidation and pulmonary edema, both of which are found in patients with COVID.
- Trial name
- NCT04542421
- Testing
- Lung ultrasound use in patients hospitalized with COVID
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
COVID-19 Disease
Study of LAU-7b for the Treatment of Coronavirus Disease 2019 (COVID-19) Disease in Adults
A randomized, double-blind, placebo-controlled Phase 2/3 Study of LAU-7b against confirmed COVID-19 Disease in hospitalized patients at a higher risk of complications.
- Trial name
- RESOLUTION (NCT04417257)
- Testing
- LAU-7b
- Where
- 29 sites in United States, Canada
- Volunteers
- 351 people
- Sponsor
- Laurent Pharmaceuticals Inc.
COVID-19
VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
This study looks at the safety and effectiveness of VIR-7831 in treating COVID-19 in people who have been hospitalized with the infection.
- Trial name
- NCT05780281
- Testing
- VIR-7831, Remdesivir
- Where
- 105 sites in United States, Denmark and 6 more
- Volunteers
- 367 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coronavirus Disease 2019
Study to Evaluate Safety and Efficacy of Carrimycin for Treatment of Severe Coronavirus Disease 2019 (COVID-19) in Hospitalized Patients
This is a randomized, multicenter, placebo-controlled, double-blind clinical study in patients hospitalized due to severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection.
- Trial name
- NCT04672564
- Testing
- Carrimycin
- Where
- 17 sites in United States, Argentina and 4 more
- Volunteers
- 93 people
- Sponsor
- Shenyang Tonglian Group CO., Ltd
Covid-19 (New Coronavirus) Infection
Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19);
This study aims to observe the long-term health-related quality of life (HRQOL) and physical performance in individuals hospitalized due to a COVID-19 infection.
- Trial name
- NCT04375709
- Testing
- Physical exercise, Education sessions
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Kantonsspital Winterthur KSW
SARS-CoV-2, Coronavirus Infection
Post-Exposure Prophylaxis for Asymptomatic SARS-CoV-2 COVID-19 Patients With choloroquinE Compounds
To create a protocol for treatment of Pakistani patients with SARS-CoV-2 infection with an intent to reduce burden on institutional healthcare services by determining efficacy of different quinone drug dosing regimens in…
- Conditions
- SARS-CoV-2, Coronavirus Infection, Asymptomatic Condition, COVID-19
- Trial name
- PEACE (NCT04346667)
- Testing
- Hydroxychloroquine Sulfate Regular dose, Hydroxychloroquine Sulfate Loading Dose, Chloroquine
- Where
- 3 sites in Pakistan
- Volunteers
- 125 people
- Sponsor
- Government of Punjab, Specialized Healthcare and Medical Education Department
Coronavirus Infections
Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-Cov-2 Virus (COVID-19)
Coronavirus (COVID-19) is a somewhat new and recognized infectious disease that is now spreading to several countries in the world, including Brazil. Hydroxychloroquine and azithromycin may be useful for treating those patients.
- Trial name
- Coalition-I (NCT04322123)
- Testing
- Hydroxychloroquine Oral Product, Hydroxychloroquine + azithromycin
- Where
- 28 sites in Brazil
- Volunteers
- 667 people
- Sponsor
- Hospital do Coracao
Sars-CoV2, Symptomatic Condition
PRophylaxis of Exposed COVID-19 Individuals With Mild Symptoms Using choloroquinE Compounds
To treat Pakistani patients with non-life threatening symptomatic SARS-CoV-2 infection with an intent to reduce burden on institutional healthcare services by determining efficacy of different chloroquine and hydroxychloroquine…
- Conditions
- Sars-CoV2, Symptomatic Condition, Covid-19
- Trial name
- PRECISE (NCT04351191)
- Testing
- Hydroxychloroquine Sulfate Regular dose, Hydroxychloroquine Sulfate Loading Dose, Chloroquine
- Where
- 4 sites in Pakistan
- Volunteers
- 137 people
- Sponsor
- Government of Punjab, Specialized Healthcare and Medical Education Department
Covid19
Convalescent Plasma as Adjunctive Therapy for Hospitalized Patients With COVID-19
This protocol provides access to investigational convalescent plasma for hospitalized patients with COVID-19. Following provision of informed consent, patients will be administered around 500 mL of convalescent plasma obtained…
- Trial name
- Co-CLARITY (NCT04567173)
- Testing
- Anti-SARS-CoV-2 convalescent plasma
- Where
- Philippines
- Volunteers
- 44 people
- Sponsor
- University of the Philippines
Stroke, COVID-19
Strength Training in Hospitalized Patients Using the Ghostly App: a Feasibility Study
The goal of this feasibility study is to evaluate the use of the Ghostly app in rehabilitation of stroke patients, elderly and patients recovering from COVID-19 or ICU patients.
- Conditions
- Stroke, COVID-19, Frailty, Muscle Weakness
- Trial name
- NCT05258500
- Testing
- Ghostly app, Blood flow restriction, Leaflet
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- Vrije Universiteit Brussel
SARS-CoV-2 Infection
SARS-CoV-2 in Stools Compared to Respiratory Viral Strains.
The aim of the study is to characterize and to quantify SARS-CoV-2 strains in stools, in comparison with the viral strains in respiratory samples, from patients hospitalized for COVID-19.
- Trial name
- Spread-COVID (NCT05567419)
- Testing
- Biological assays
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
SARS-CoV-2, Hypoxia
Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment
Abstract Background: Clinicians in pulmonary critical care medicine and critical care medicine considered dapsone administration to treat SARS-CoV-2 inflammasome.
- Conditions
- SARS-CoV-2, Hypoxia, ARDS
- Trial name
- NCT04918914
- Testing
- Dapsone 100 MG
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hunt Regional Medical Center
Covid19, Thrombosis
Registry of Hospitalized Patients in University Hospital Dubrava Respiratory Center
Aim of this project is to understand clinical features, clinical outcomes and efficacy and safety profiles of different therapies by analyzing a cohort of COVID-19 patients hospitalized and treated in a tertiary-level…
- Conditions
- Covid19, Thrombosis, Bleeding, Sepsis
- Trial name
- COVID-19 (NCT05151094)
- Testing
- Observation
- Where
- Croatia
- Volunteers
- 6,000 people
- Sponsor
- University Hospital Dubrava
Covid19, Pregnancy Related
Clinical and Immunologic Impact of Perinatal SARS-CoV-2 (COVID-19) Infection
This is a multi-center prospective study that aims to investigate the clinical and immunologic impact of SARS-CoV-2 infection in pregnant women and neonates.
- Conditions
- Covid19, Pregnancy Related, Neonatal Infection
- Trial name
- NCT04362956
- Where
- Argentina
- Volunteers
- 114 people
- Sponsor
- Fundacion Infant
Pulmonary Embolism
Registry of the Evolution of Diagnosed and/or Hospitalized Patients for Pulmonary Embolism During the Covid-19 Pandemic
The purpose of the study COVID-EP is to classify all the complications occurring after the diagnosis of pulmonary embolism in patients tested initially COVID-19 positive and negative by RT-PCR (on nasopharyngeal sample) during…
- Trial name
- COVID-EP (NCT04465656)
- Testing
- Serology test for COVID-19
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Hospital St. Joseph, Marseille, France
COVID-19
Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia
The main objective of our study is to determine if treatment with sirolimus can improve clinical outcomes in hospitalized patients with COVID-19.
- Trial name
- SCOPE (NCT04341675)
- Testing
- Sirolimus
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Cincinnati
Virus Diseases
Trial to Evaluate the Safety and Efficacy of Maraviroc in Patients Hospitalized for Coronavirus Disease 2019 (COVID-19)
Maraviroc (MVC) is a drug, very well tolerated, it has been seen that MVC has properties of modulating the immune system, exerting an anti-inflammatory effect in different diseases.
- Trial name
- COVIMAR (NCT04710199)
- Testing
- Maraviroc experimental group, Standard treatment
- Where
- 2 sites in Spain
- Volunteers
- 44 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Decay, Dental, Missing Teeth
Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients
Two hundred individuals will be formed according to the study and control groups: Group-1: coronavirus 2 (Covid-19) (+) patients (n=100) and Group-2: Healthy individuals (in which the volunteers will be included due to group-1)…
- Conditions
- Decay, Dental, Missing Teeth, COVID-19, Cytokine Storm
- Trial name
- NCT05476848
- Testing
- ELISA test for Cytokines
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ege University
COVID-19, SARS-CoV-2
Efficacy and Safety of JS016 in Patients With SARS-CoV-2 Infection (COVID-19)
The human monoclonal antibody CB6 showed potent neutralization activity in vitro against SARS-CoV-2. CB6-LALA (also called JS016) has been developed for clinical use.
- Trial name
- NCT04931238
- Testing
- JS016
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
COVID-19
Trial to Study the Efficacy and Safety of BEJO Red Ginger in COVID-19 Patients With Mild Symptoms
This study is a randomized, double-blind, placebo-controlled clinical trial to investigate the safety and efficacy of BEJO Red Ginger in hospitalized adult (18 - 50 years old) COVID-19 patients with mild clinical manifestations.
- Trial name
- NCT05277155
- Testing
- BEJO Red Ginger Extract
- Where
- Indonesia
- Volunteers
- 168 people
- Sponsor
- Research Center for Chemistry, National Research and Innovation Agency of Indonesia