Clinical trials: Hospitalized COVID-19
COVID-19
Physical Activity and the Course of COVID-19
Being active has a beneficial effect on human immunology. Patients hospitalized for COVID-19 (coronavirus disease 2019) will be surveyed for their prior physical activity.
- Trial name
- NCT05200767
- Testing
- completing surveys
- Where
- 2 sites in Poland
- Volunteers
- 140 people
- Sponsor
- Wroclaw Medical University
COVID-19
#StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19
BACKGROUND Despite drastic quarantine measures, COVID-19 continues to propagate and threatens global healthcare systems by saturating their capacity with high transmissibility and the particularly protracted length of stay needed…
- Trial name
- #StayHome (NCT04385264)
- Testing
- Hydroxychloroquine, Mannitol
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization
This phase Ib/II trial studies the side effects and best dose of ibrutinib and how well it works in treating patients with COVID-19 requiring hospitalization.
- Conditions
- Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Monoclonal B-Cell Lymphocytosis
- Trial name
- NCT04439006
- Testing
- Best Practice, Ibrutinib
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jennifer Woyach
COVID-19
Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial
This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization.
- Trial name
- CATCO (NCT04330690)
- Testing
- Artesunate, Imatinib, Infliximab
- Where
- 53 sites in Canada
- Volunteers
- 2,900 people
- Sponsor
- Sunnybrook Health Sciences Centre
Covid19
Reliability of Standardized Protocol of Ultrasound of the Lungs in Prediction of Severity of Covid-19 Infection
Ultrasound can reliably detect morphologic changes associated with pneumonia. Additionally, protocols were elaborated which unify the investigation procedure and improve the intra- and interrater reliability.
- Trial name
- NCT04513210
- Where
- Poland
- Volunteers
- 94 people
- Sponsor
- Jagiellonian University
COVID-19 Respiratory Infection
Severity of COVID-19 and Vitamin D Supplementation
Purpose of the study: to analyze the interlinks between serum 25(OH)D level and severity of new coronavirus infection (COVID-19) in hospitalized patients, as well as the effect of adding colecaciferol to standard therapy for…
- Trial name
- NCT05166005
- Testing
- vitamin D
- Where
- Russia
- Volunteers
- 350 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Deep Venous Thrombosis
Deep Venous Thrombosis in Non-severe COVID-19 Patients Hospitalized for a Neurovascular Pathology
Severe SARS-CoV-2 infection, responsible of COVID-19, is accompanied by many venous thromboembolic events. Antithrombotic treatment is the cornerstone of management of many neurovascular diseases (NVDs) and the benefit-risk ratio…
- Trial name
- VT-Covid-19 (NCT04452422)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19
Transcranial Non-invasive Electrical Stimulation of the Vagus Nerve in Hospitalized Moderate-to-severe COVID-19 Patients
Subtle Pulse Electro-biological Recovery Apparatus (SPERA) is an innovative device which delivers digital subliminal pulse stimulation trans cranially to auricular branches of the central nervous system and modulates the…
- Trial name
- NCT06767241
- Testing
- Non-invasive auricular vagus nerve stimulation, Standard Medical Therapy
- Where
- Romania
- Volunteers
- 83 people
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
SARS-CoV 2
Efficacy of Tocilizumab on Patients With COVID-19
This is a randomized, double blind, multi-center study to evaluate the effects of tocilizumab compared to placebo on patient outcomes in participants with confirmed SARS-CoV-2 infection and evidence of systemic inflammation.
- Trial name
- NCT04356937
- Testing
- Tocilizumab
- Where
- 3 sites in United States
- Volunteers
- 243 people
- Sponsor
- Massachusetts General Hospital
COVID-19, SARS-CoV-2
A Trial of Remdesivir in Adults With Mild and Moderate COVID-19
In December 2019, Wuhan, in Hubei province, China, became the center of an outbreak of pneumonia of unknown cause. In a short time, Chinese scientists had shared the genome information of a novel coronavirus (SARS-CoV-2) from…
- Trial name
- NCT04252664
- Testing
- Remdesivir
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Capital Medical University
Covid19, SARS-CoV Infection
Prognostic Value of Flow-mediated Dilation in Hospitalized COVID-19 Patients
This study will evaluate the associations between vascular parameters and clinical outcomes in patients hospitalized with COVID-19.
- Trial name
- NCT04714125
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- University of Sao Paulo General Hospital
Covid-19
Study to Evaluate STI-1499 (COVI-GUARD) in Patients With Moderate COVID-19
Randomized, placebo-controlled study to evaluate the safety, pharmacokinetics and efficacy of a single dose of STI-1499 (COVI-GUARD™) in hospitalized patients with moderate COVID-19
- Trial name
- NCT04454398
- Testing
- COVI-GUARD, Standard of Care
- Sponsor
- Sorrento Therapeutics, Inc.
Covid19
Effectiveness of Convalescent Plasma in Hospitalized Patients With COVID-19
Multicenter retrospective cohort study from June to August 2020 on hospitalized COVID-19 patients admitted to Al-Hakeem and Al-Amal hospital in Al-Najaf Governorate, Iraq, in order to evaluating the effectiveness of plasma…
- Trial name
- NCT04764747
- Where
- 2 sites in Iraq
- Volunteers
- 400 people
- Sponsor
- Kufa University
Covid-19, Stress Disorders, Post-Traumatic
Psychological Impact of the Hospitalization of a Family Member in Intensive Care for Covid-19 Infection
The hospitalization of a patient in intensive care is a traumatic experience for his family members. With the current COVID-19 epidemic, in view of the high risk of contamination, drastic measures to limit the transmission are…
- Conditions
- Covid-19, Stress Disorders, Post-Traumatic, Anxiety, Depression
- Trial name
- Familles-COVID (NCT04385121)
- Testing
- Questionnary
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19
Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19
This will be a phase 1a randomized, open label, multi-center study with approximately 24 subjects. All subjects will receive standard of care (SOC) per institutional guidelines for treatment of hospitalized patients with COVID-19…
- Trial name
- CRISIS (NCT04425252)
- Testing
- Brequinar, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 25 people
- Sponsor
- Clear Creek Bio, Inc.
Covid19
A Real-world Evidence Study of BNT162b2 mRNA Covid-19 Vaccine in Brazil
The present test-negative design study aims to estimate the real-world effectiveness of Pfizer-BioNTech BNT162b2 mRNA vaccine on symptomatic SARS-CoV-2 infection and its consequences following a mass vaccination campaign in the…
- Trial name
- NCT05052307
- Testing
- Pfizer/BioNTech BNT162b2 mRNA COVID-19 vaccine, CoronaVac COVID-19 vaccine, ChAdOx1 nCoV-19 Covid-19 Vaccine
- Where
- 3 sites in Brazil
- Volunteers
- 4,574 people
- Sponsor
- Hospital Moinhos de Vento
Patient Hospitalized in Disease Infectious Unit, Patient Hospitalized in Intensive Reanimation Unit
Study of the Consequences of Infection on Compliance of Modalities of Decisions of Limitations and Stops of Treatments (COVID-19-LAT)
This survey is performed to examine if during the Covid's crisis, the practitionner's have respected the modalities of the law about the end of life, in particular concerning limitations and stop of therapeutics
- Conditions
- Patient Hospitalized in Disease Infectious Unit, Patient Hospitalized in Intensive Reanimation Unit, Patient Hopsitalized in Internal Medicine Unit
- Trial name
- COVID-19-LAT (NCT04452487)
- Testing
- decisions of limitations and stop processing
- Where
- 3 sites in France
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Clermont-Ferrand
Covid19
Public Health Emergency: SOLIDARITY TRIAL Philippines
This study is an adaptive, randomized, open-label, controlled clinical trial utilizing an adaptive design to compare effects of repurposed drugs with local standard of care alone on major inpatient hospital outcomes.
- Trial name
- NCT05024006
- Testing
- Remdesivir, Hydroxychloroquine, Lopinavir / Ritonavir
- Where
- 25 sites in Philippines
- Volunteers
- 1,314 people
- Sponsor
- University of the Philippines
SARS-CoV-2 Infection
Pulmonary Function in Non-hospitalized Adults and Children After Mild COVID-19
The study investigates whether patients with mild SARS-CoV-2 infection, who stayed at home during their infection and weren't hospitalized, have any persisting sequelae in pulmonary function.
- Trial name
- NCT06318208
- Testing
- lung function testing
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- University of Rostock
COVID-19 Infection
Registry of Management Strategies for Patients With COVID-19 in Healthcare Establishments
The purpose of the study is to describe medical care strategies implemented by healthcare establishments for patients affected by COVID-19
- Trial name
- HOPICOV (NCT05069389)
- Testing
- Data collection
- Where
- France
- Volunteers
- 2,071 people
- Sponsor
- Centre Hospitalier Emile Roux