Clinical trials: Hospitalized COVID-19
Diabetes, Covid-19
Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized Patients
This is a randomized controlled trial of isolated patients with diabetes admitted to Nordsjællands Hospital with or without COVID-19-pneumonia.
- Conditions
- Diabetes, Covid-19, Infection
- Trial name
- CGM-ISO (NCT04430608)
- Testing
- Dexcom G6
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Nordsjaellands Hospital
Covid-19
Clinical Evolution and Becoming of Adult Patients Infected With Covid-19 Hospitalized at Strasbourg University Hospitals
A SARS-CoV-2 infection emerged in China in December 2019, the severity of which is linked to acute respiratory distress syndrome1.
- Trial name
- NCT04706260
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19
A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19
The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19.
- Trial name
- NCT04411628
- Testing
- LY3819253
- Where
- 11 sites in United States
- Volunteers
- 26 people
- Sponsor
- Eli Lilly and Company
COVID-19
Mortality, Gravity Predictive Factors and Clinical Evolution of Older COVID-19 Patients in Short Geriatric Services.
Since the beginning of the year 2020, clinical characteristics of a new disease as the global COVID-19 epidemic has spread in France.
- Trial name
- GERICOVID (NCT05455892)
- Testing
- Clinical data collection during hospitalization in short geriatric units.
- Where
- 5 sites in France
- Volunteers
- 450 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Failure, COVID-19
Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization
Acute respiratory distress syndrome (ARDS) is a major complication among patients with severe disease. In a report of 138 patients with COVID-19, 20% developed ARDS at a median of 8 days after the onset of symptoms, with 12.3% of…
- Trial name
- PAPR (NCT04368000)
- Testing
- Intermittent prone positioning instructions, Usual care positioning with no instructions
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
COVID-19 Pneumonia
Pirfenidone in Adult Hospitalized Patients With COVID-19
This center intends to conduct a multicenter, randomized, placebo-controlled study to evaluate the effectiveness and safety of Nintedanib ethanesulfonate soft capsule in the treatment of pulmonary fibrosis in patients with…
- Trial name
- NCT05713292
- Testing
- Pirfenidone Oral Product
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Capital Medical University
COVID-19
Effectiveness of COVID-19 Vaccine for Prevention of COVID-19 in the Dominican Republic
This study is a multisite ,grouped test-negative case-control , phase Ⅳ clinical trial of an inactivated SARS-CoV-2 vaccine (CoronaVac) manufactured by Sinovac Research and Development Co., Ltd.The purpose of this study is to…
- Trial name
- NCT04974164
- Testing
- Inactivated COVID-19 Vaccine
- Where
- 10 sites in Dominican Republic
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
COVID-19
Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Participants With Acute COVID-19 Disease
This study evaluates the efficacy and safety of intravenous (IV) infusions of pamrevlumab when compared with placebo in participants who are hospitalized with acute COVID-19 disease.
- Trial name
- NCT04432298
- Testing
- Pamrevlumab
- Where
- 4 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kyntra Bio
COVID-19, AMS-H-03
Hydrogen-Oxygen Generator With Nebulizer for Rehabilitation Treatment of COVID-19
This is a prospective, multicenter, randomized, controlled, superiority clinical trial, with the test group expected to be superior to the control group in the primary evaluation endpoints (changes in Borg score and PSQI index at…
- Conditions
- COVID-19, AMS-H-03, Hydrogen-oxygen Gas
- Trial name
- NCT05504460
- Testing
- Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03, basic treatment
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Shanghai Zhongshan Hospital
COVID-19
The South Proxa-Rescue AndroCoV Trial Against COVID-19
The purpose of this study is to investigate the efficacy of proxalutamide or hospitalized moderate-to-severe COVID-19 patients.
- Trial name
- NCT05126628
- Testing
- Proxalutamide
- Where
- Brazil
- Volunteers
- 133 people
- Sponsor
- Corpometria Institute
COVID-19
COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection
The primary objective of the study is to assess the virologic efficacy of REGN10933+REGN10987 across different intravenous and subcutaneous doses compared to placebo.
- Trial name
- NCT04666441
- Testing
- REGN10933+REGN10987 combination therapy
- Where
- 57 sites in United States
- Volunteers
- 1,149 people
- Sponsor
- Regeneron Pharmaceuticals
Covid19
Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients
The primary objective is to evaluate the safety and efficacy of intravenous (IV) infusion of Ang (1-7) compared to placebo with respect to time to recovery, disease severity, need for mechanical ventilation or extracorporeal…
- Trial name
- NCT04570501
- Testing
- Angiotensin-(1-7)
- Where
- United States
- Sponsor
- Stanford University
COVID - 19
Open Label Study to Compare Efficacy, Safety and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to "no Treatment" in SARS CoV 2 Virus
Patients with COVID-19 which are 60 years old or above or with comorbidities are at risk of deteriorating and developing severe illness.
- Trial name
- COSTA (NCT04355052)
- Testing
- hydroxychloroquine in combination with camostat mesylate, Hydroxychloroquine in combination of Azithromycin
- Where
- 2 sites in Israel
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
Hospitalized Patients With Covid-19 Pneumonia
Use of Ascorbic Acid in Patients With COVID 19
Different studies showed that ascorbic acid (vitaminC) positively affects the development and maturation of T-lymphocytes, in particular NK (natural Killer) cells involved in the immune response to viral agents.
- Trial name
- NCT04323514
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Coronavirus Disease (COVID-19)
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Researchers are looking for other ways to prevent severe illness from COVID-19. COVID-19 is a virus that most often causes mild flu or cold-like symptoms.
- Trial name
- MOVe-NOW (NCT06667700)
- Testing
- Molnupiravir
- Where
- 227 sites in United States, Argentina and 22 more
- Volunteers
- 3,082 people
- Sponsor
- Merck Sharp & Dohme LLC
COVID19, Intensive Care Unit
Assessment of Efficacy and Safety of Tocilizumab Compared to DefeROxamine, Associated With Standards Treatments in COVID-19 (+) Patients Hospitalized In Intensive Care in Tunisia
Assessment of Efficacy and Safety of Tocilizumab Compared to DefeROxamine, associated with standards treatments in COVID-19 (+) patients, Hospitalized In Intensive care in Tunisia. Multicentric, comparative, randomized study.
- Trial name
- TRONCHER (NCT04361032)
- Testing
- Tocilizumab Injection, Deferoxamine
- Where
- Tunisia
- Volunteers
- 260 people
- Sponsor
- Abderrahmane Mami Hospital
Covid19
Risk Factors and Prognoses in Patients Hospitalized for COVID-19
Multicenter and observational study. The study will include patients admitted to hospitals in the Lleida health region with confirmed COVID-19. Follow-up will be carried out up to six months after hospital discharge.
- Trial name
- NCT04824677
- Testing
- Hospital treatment of COVID disease
- Where
- 2 sites in Spain
- Volunteers
- 971 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
COVID-19
Chloroquine as Antiviral Treatment in Coronavirus Infection 2020
The aim of the study is to evaluate whether the therapy with chloroquine phosphate (CQ, in combination with telemedical approach) in addition to standard care is effective and safe in reducing composite endpoint of…
- Trial name
- NCT04331600
- Testing
- Chloroquine phosphate, Telemedicine
- Where
- 2 sites in Poland
- Volunteers
- 16 people
- Sponsor
- Wroclaw Medical University
Covid19, Coronavirus Disease 2019
Tele-Physiotherapy After COVID-19 Hospitalization
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), is a multisystem infectious disease which has led to a global pandemic.
- Trial name
- NCT04895371
- Testing
- Tele-physiotherapy group, Control group
- Where
- Iran
- Volunteers
- 72 people
- Sponsor
- Tehran University of Medical Sciences
COVID 19, Rehabilitation
Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients
Conventional in-hospital mobility programs are challenging to deliver to hospitalized infected patients (e.g., COVID-19) due to infection risk to staff, staffing shortages, and potential exposure of other patients.
- Conditions
- COVID 19, Rehabilitation, Inpatient, Hospitalized
- Trial name
- NCT04743401
- Testing
- Tele-exergaming Tablet
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development