Clinical trials: Hospitalized COVID-19
SARS-CoV2 Infection
Receptive Music Therapy on Anxiety and Vital Parameters in Hospitalized Covid-19 Patients.
Hospitalized patients for Covid-19 are extremely isolated from their families for a long and uncertain period of time .This traumatic separation makes patients vulnerable to different degrees of stress disorders as well as…
- Trial name
- MADC-19 (NCT05077306)
- Testing
- music therapy group
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Coronavirus Disease 2019 (COVID-19)
Convalescent Plasma (PC) and Human Intravenous Anti-COVID-19 Immunoglobulin (IV Anti COVID-19 IgG) in Patients Hospitalized for COVID-19.
A randomized, open-label, multicenter, three-arm clinical trial to study the efficacy and safety of passive immunotherapy (convalescent plasma and anti-COVID-19 human immunoglobulin) compared to the standard treatment in Colombia.
- Trial name
- NCT04395170
- Testing
- COVID-19 convalescent plasma, Anti-COVID-19 human immunoglobulin, Standard (specific) therapy for COVID-19
- Where
- Colombia
- Volunteers
- 75 people
- Sponsor
- Lifefactors Zona Franca, SAS
COVID-19
Dimolegin® (60 mg) for Patients With Moderate COVID-19: A Non-Interventional Study
A multicenter, open-label, non-interventional study evaluates the safety and tolerability of oral Dimolegin® (60 mg once daily) for thromboprophylaxis in hospitalized adults (≥18 years) with moderate COVID-19 in real clinical…
- Trial name
- NCT07134738
- Testing
- Dimolegin
- Where
- 6 sites in Russia
- Volunteers
- 184 people
- Sponsor
- Avexima Diol LLC
Covid19, Coronavirus Disease
Survival and 30-days Hospital Outcome in COVID-19 Patients in Upper Egypt
Through history, there have been plenty of pandemics however; the social response to corona virus disease (COVID-19) is unparalleled.
- Conditions
- Covid19, Coronavirus Disease, SARS-CoV-2
- Trial name
- NCT04488588
- Testing
- Kaplan Meier analysis
- Where
- 2 sites in Egypt
- Volunteers
- 1,064 people
- Sponsor
- Assiut University
Coronavirus, COVID
A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19
This was a randomized, double-blind, placebo-controlled, 29-day study to assess the efficacy and safety of axatilimab plus standard of care (SOC), compared with placebo plus SOC, in participants with respiratory signs and…
- Conditions
- Coronavirus, COVID, ARDS, Cytokine Storm
- Trial name
- NCT04415073
- Testing
- SNDX-6352
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Syndax Pharmaceuticals
Severe Acute Respiratory Syndrome
Camostat Mesilate Treating Patients With Hospitalized Patients With COVID-19
To determine if the reduction in TMPRSS2 activity via direct inhibition with Camostat mesilate combined with standard of care (SOC) treatment will increase the proportion of patients alive and free from respiratory failure at Day…
- Trial name
- RECOVER (NCT04470544)
- Testing
- Camostat Mesilate, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Alan Bryce
COVID, Corona Virus Infection
Predicting Favorable Outcomes in Hospitalized Covid-19 Patients
Testing use of predictive analytics to predict which COVID-19+ patients are at low risk for an adverse event (ICU transfer, intubation, mortality, hospice discharge, re-presentation to the ED, oxygen requirements exceeding nasal…
- Conditions
- COVID, Corona Virus Infection, Adverse Event
- Trial name
- NCT04570488
- Testing
- EPIC risk score display
- Where
- United States
- Volunteers
- 1,415 people
- Sponsor
- NYU Langone Health
COVID-19
Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients
Given the current lack of an effective drug or therapy, a clinical trial to better understand the safety and efficacy of therapeutic plasma exchange (TPE) in COVID-19 patients is urgently needed.
- Trial name
- NCT04592705
- Testing
- Therapeutic plasma exchange
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Larkin Community Hospital
SARS-CoV-2 Acute Respiratory Disease, SARS-CoV2 Infection
Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients
To explore the efficacy of treatment of pulmonary cytokine storm induced by SARS-CoV2 with a monoclonal antibody to IL-2 (Basiliximab) in addition to current standard of care vs current standard of care with the primary efficacy…
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, SARS-CoV2 Infection, Cytokine Storm
- Trial name
- FWCSWG-IL-2 (NCT05013034)
- Testing
- Basiliximab Injection
- Volunteers
- 300 people
- Sponsor
- Fort Worth Clinical Sciences Working Group
Post-COVID-19 Syndrome, Long COVID
ImPROving Quality of LIFe in the Long COVID Patient
The purpose of this study is to investigate the efficacy of orally administered nirmatrelvir/ritonavir compared with placebo/ritonavir to improve quality of life in non-hospitalized adult participants suffering from post-acute…
- Conditions
- Post-COVID-19 Syndrome, Long COVID, Long Covid19, COVID-19
- Trial name
- PROLIFIC (NCT05823896)
- Testing
- Nirmatrelvir/ritonavir
- Where
- Sweden
- Volunteers
- 219 people
- Sponsor
- Karolinska Institutet
COVID-19
A Study Evaluating Tocilizumab in Pediatric Patients Hospitalized With COVID-19
This is a single-arm, open-label study to assess the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of tocilizumab (TCZ) for the treatment of pediatric patients from birth to less than 18 years old…
- Trial name
- NCT05164133
- Testing
- Tocilizumab
- Where
- 25 sites in United States, Brazil and 9 more
- Volunteers
- 2 people
- Sponsor
- Hoffmann-La Roche
COVID-19, SARS-CoV-2
Investigation the Effect of Montelukast in COVID-19
Small molecule inhibitors have previously been investigated in different studies as possible therapeutics in the treatment of SARS-CoV-2.
- Trial name
- NCT04718285
- Testing
- Montelukast Oral Tablet, Montelukast plus Favicovir (Favipiravir), Favicovir (Standard Treatment)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 380 people
- Sponsor
- Bahçeşehir University
Covid-19, Pneumonia
The Effects of Pulmonary Physiotherapy Treatments on Patients With COVID-19
The aim of this study is to evaluate the efficacy of pulmonary physiotherapy on respiratory functions in hospitalized patients with Novel Coronavirus 2019 pneumonia.
- Conditions
- Covid-19, Pneumonia, SARS Pneumonia
- Trial name
- NCT04357340
- Testing
- Pulmonary Physiotherapy Techniques
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
COVID-19, Vaccination
COVID-19 Vaccination AZV 2021-2023
The study is aimed at the clinical and laboratory characteristics of patients with completed vaccination against SARS-CoV-2 admitted to the hospital in the standard ward and intensive care unit due to the severe course of…
- Conditions
- COVID-19, Vaccination, Immunity, Respiratory Failure
- Trial name
- NCT05589233
- Testing
- Vaccionation eighter started or full course
- Where
- Czechia
- Volunteers
- 3,000 people
- Sponsor
- University Hospital Hradec Kralove
COVID
Prevalence of Critical Forms of CoVid-19 in Patients With Chronic Respiratory Disease
A new Coronavirus (SARS-CoV-2) emerged in Wuhan Province, China in December 2019 and rapidly spread around the world. To date, the data in the literature regarding the clinical and epidemiological characteristics of severe forms…
- Trial name
- CRITICoVid (NCT04407169)
- Testing
- no intervention
- Where
- France
- Volunteers
- 617 people
- Sponsor
- Central Hospital, Nancy, France
Cardiovascular Diseases, COVID
Cardiovascular Manifestations of COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the novel coronavirus disease 2019 (COVID-19). The first reports of COVID-19 came from Wuhan, China in December of 2019.
- Trial name
- NCT04335630
- Testing
- Electrocardiogram, telemetry, echocardiogram, laboratory values
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Memorial Hermann Health System
Covid19
Effect of Tenofovir/Emtricitabine in Patients Recently Infected With SARS-COV2 (Covid-19) Discharged Home
COVID-19 pandemic is currently affecting the globe. To date, there is no effective oral therapy against SARS-CoV2 infection. The investigators propose to test as a repurposing drug combination, a short course of tenofovir…
- Trial name
- AR0-CORONA (NCT04685512)
- Testing
- tenofovir disoproxil and emtricitabine
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Corona Virus Infection
Impact of Colchicine in Hospitalized Colombian Patients With COVID-19
This is a phase IIIa, prospective, open-label, randomized, parallel-group study designed to evaluate the efficacy and safety of oral colchicine plus standard therapy versus standard therapy in the clinical course of SARS-CoV-2…
- Trial name
- (COLCOVID19) (NCT04539873)
- Testing
- Colchicine 0.5 MG, CONTROL GROUP
- Where
- Colombia
- Volunteers
- 128 people
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
COVID-19
Assessment of Clinical Effects of Coenzyme Q10 Levels in COVID-19 Patients in Intensive Care Unit
The study will be done in Hacettepe University Anesthesiology and Reanimation Intensive Care Unit. The investigators will accept COVID-19 diagnosed or suspected patients to the ICU.
- Trial name
- NCT05058716
- Testing
- blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hacettepe University
Corona Virus Disease (COVID-19), Respiratory Distress Syndrome
Fenofibrate for Patients With COVID-19 Requiring Hospitalization
This is an open-label run-in followed by a randomized, double-blind drug treatment study of COVID-19 infected patients requiring inpatient hospital admission.
- Conditions
- Corona Virus Disease (COVID-19), Respiratory Distress Syndrome, SARS-CoV-2 Infection
- Trial name
- FENOC (NCT04661930)
- Testing
- TriCor® 145mg tablets, Usual care
- Where
- 3 sites in Israel
- Volunteers
- 55 people
- Sponsor
- Yaakov Nahmias