Clinical trials: Hospitalized COVID-19
Covid19
COVID-19 Risk Assessment for Hospitalization Outcomes and Epidemiology Efficacy
Researchers are creating real-time epidemiology registry to evaluate the efficacy of COVID-19 subject risk assessment scores based on recording of symptoms, biomarkers, chronic illness and mental health assessments with digital…
- Trial name
- COROMEC (NCT04678193)
- Testing
- Coromec Registry with ECL-19
- Where
- 3 sites in United States, India and 1 more
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- Aventyn, Inc.
Problems Related to Life-Management Difficulty
Beyond COVID-19: Supporting Resilience With a Trauma-informed Music Composition Program
This study explores the feasibility and acceptability of a music composition intervention to support resilience in survivors of serious illness hospitalized during the COVID-19 pandemic.
- Trial name
- NCT05727514
- Testing
- music composition
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
COVID-19
Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19
Phase 2: The primary objective of the study is to evaluate the clinical efficacy of sarilumab relative to the control arm in adult patients hospitalized with COVID-19 regardless of disease severity strata.
- Trial name
- NCT04315298
- Testing
- Sarilumab
- Where
- 62 sites in United States
- Volunteers
- 1,912 people
- Sponsor
- Regeneron Pharmaceuticals
Hospitalized Patients With Covid-19 Pneumonia
Use of Ascorbic Acid in Patients With COVID 19
Different studies showed that ascorbic acid (vitaminC) positively affects the development and maturation of T-lymphocytes, in particular NK (natural Killer) cells involved in the immune response to viral agents.
- Trial name
- NCT04323514
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Covid19, Thrombosis
Registry of Hospitalized Patients in University Hospital Dubrava Respiratory Center
Aim of this project is to understand clinical features, clinical outcomes and efficacy and safety profiles of different therapies by analyzing a cohort of COVID-19 patients hospitalized and treated in a tertiary-level…
- Conditions
- Covid19, Thrombosis, Bleeding, Sepsis
- Trial name
- COVID-19 (NCT05151094)
- Testing
- Observation
- Where
- Croatia
- Volunteers
- 6,000 people
- Sponsor
- University Hospital Dubrava
Covid19, Coronavirus Disease
Survival and 30-days Hospital Outcome in COVID-19 Patients in Upper Egypt
Through history, there have been plenty of pandemics however; the social response to corona virus disease (COVID-19) is unparalleled.
- Conditions
- Covid19, Coronavirus Disease, SARS-CoV-2
- Trial name
- NCT04488588
- Testing
- Kaplan Meier analysis
- Where
- 2 sites in Egypt
- Volunteers
- 1,064 people
- Sponsor
- Assiut University
SARS-CoV-2
Interferon Lambda Therapy for COVID-19
The main purpose of this research study is to test the safety and effectiveness of an investigational drug peginterferon lambda-1a in treating COVID-19.
- Trial name
- NCT04388709
- Testing
- Peginterferon Lambda-1A
- Sponsor
- Icahn School of Medicine at Mount Sinai
Covid19, Corona Virus Infection
Nitazoxanide Therapy for Patients With COVID-19 Pneumonia
Multicenter, randomized, placebo-controlled, parallel, blinded, interventional, treatment clinical trial with two arms. Population: 500 Hospitalized patients with pneumonia derived from COVID-19 (Coronavirus Disease-19), either…
- Conditions
- Covid19, Corona Virus Infection, Pneumonia, Viral
- Trial name
- NCT04561219
- Testing
- Nitazoxanide
- Where
- Brazil
- Volunteers
- 500 people
- Sponsor
- Universidade Federal do Rio de Janeiro
COVID-19
COVID-19 Clinical Status Associated With Outcome Severity: An Unsupervised Machine Learning Approach
Since the beginning of the COVID-19 pandemic, 195 million people have been infected and 4.2 million have died from the disease or its side-effects.
- Trial name
- NCT05119465
- Where
- Greece
- Volunteers
- 268 people
- Sponsor
- Aristotle University Of Thessaloniki
COVID-19
Famotidine Outpatient COVID-19 Treatment Study
A retrospective case series of patients who self-medicated with Famotidine during coronavirus disease 2019 (COVID-19). The study will collect de-identified patient reported outcome measures of patients with confirmed COVID-19 who…
- Trial name
- NCT04389567
- Testing
- Famotidine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwell Health
COVID-19
A Study of Efficacy and Safety of Azvudine vs. Nirmatrelvir-Ritonavir in the Treatment of COVID-19 Infection
The COVID-19 pandemic has become a major public health challenge, and the treatment options for the disease are currently limited.
- Trial name
- NCT05697055
- Testing
- Azvudine, Nirmatrelvir-Ritonavir
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Shandong Provincial Hospital
COVID-19 Infection
Registry of Management Strategies for Patients With COVID-19 in Healthcare Establishments
The purpose of the study is to describe medical care strategies implemented by healthcare establishments for patients affected by COVID-19
- Trial name
- HOPICOV (NCT05069389)
- Testing
- Data collection
- Where
- France
- Volunteers
- 2,071 people
- Sponsor
- Centre Hospitalier Emile Roux
COVID-19
MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
This study looks at the safety and effectiveness of MP0420 in treating COVID-19 in people who have been hospitalized with the infection.
- Trial name
- NCT05780463
- Testing
- MP0420, Remdesivir
- Where
- 105 sites in United States, Denmark and 8 more
- Volunteers
- 485 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infections, Coronavirus
Observational Open Study of Polyoxidonium in Hospitalized Patients With COVID-19
The study is designed as an open observational non-comparative study of Polyoxidonium®, lyophilizate for solution for injections and topical application, 12 mg in hospitalized patients with coronavirus disease (COVID-19).
- Trial name
- NCT04542226
- Testing
- Polyoxidonium
- Where
- 5 sites in Belarus, Russia
- Volunteers
- 81 people
- Sponsor
- NPO Petrovax
COVID-19, Sars-CoV2
Effects of COVID-19 Convalescent Plasma (CCP) on Coronavirus-associated Complications in Hospitalized Patients
The purpose of this study assess the efficacy and safety of anti-SARS-CoV-2 convalescent plasma in hospitalized patients with acute respiratory symptoms up to 14 days after the onset of initial symptoms.
- Trial name
- CAPRI (NCT04421404)
- Testing
- COVID-19 Convalescent Plasma (CCP)
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- Priscilla Hsue, MD
Coronavirus Infections
Arrhythmic Manifestations and Management in Hospitalized COVID-19 Patients
Although arrhythmias appear to be common in COVID-19 patients, arrhythmia mechanisms and characteristics, predisposing factors, incidence of sudden cardiac death and predictors, therapeutic strategies employed as well as long…
- Trial name
- NCT04465552
- Testing
- Patients received standard of care treatment during hospitalization
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Covid-19, Sars-CoV2
Safety and Efficacy of Viusid and Asbrip in Hospitalized Patients Infected by SARS-Cov-2 With COVID-19
This is a two-arm, open-label, randomized, phase 2, controlled center study to assess the safety and efficacy of Viusid and Asbrip in patients with mild to moderate symptoms of respiratory disease caused by 2019 coronavirus…
- Conditions
- Covid-19, Sars-CoV2, Diabete Mellitus, Cardiopathy
- Trial name
- NCT04407182
- Testing
- Viusid and Asbrip
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Catalysis SL
COVID-19, Pneumonia
A Study of LY3127804 in Participants With COVID-19
A randomized, double-blind, placebo-controlled, clinical trial of LY3127804 in participants who are hospitalized with pneumonia and presumed or confirmed COVID-19.
- Trial name
- NCT04342897
- Testing
- LY3127804
- Where
- 13 sites in United States
- Volunteers
- 95 people
- Sponsor
- Eli Lilly and Company
Covid19, Hypoxemia
Evaluation of a Low-cost CPAP Device on Hospitalized COVID-19 Patients
The aim of this study is to evaluate the preliminary safety and performance of a low-cost locally-made Venturi-based Non-invasive Positive Pressure Ventilator (NIPPV) device for hypoxemic COVID-19 patients.
- Trial name
- OxyJet-CPAP (NCT04681859)
- Testing
- High Flow Nasal Oxygen (HFNO) treatment, Continuous Positive Airway Pressure (CPAP) therapy using OxyJet
- Where
- Bangladesh
- Volunteers
- 45 people
- Sponsor
- Bangladesh University of Engineering and Technology
COVID-19 Pneumonia
Real-world Evidence of COVID-19 Vaccines Effectiveness
This is an observational case-control study to evaluate COVID-19 vaccine effectiveness against hospitalisation with COVID-19 related conditions in St. Petersburg, Russia.
- Trial name
- NCT04981405
- Testing
- COVID-19 Vaccines
- Where
- 2 sites in Russia
- Volunteers
- 182 people
- Sponsor
- Ivan S Moiseev