Clinical trials: Hospitalized COVID-19
COVID-19 Infection
Efficacy of Hydroxychloroquine, Telmisartan and Azithromycin on the Survival of Hospitalized Elderly Patients With COVID-19
In November 2019, Wuhan city in China, became the center of an outbreak of pneumonia due to a novel coronavirus SARS-CoV-2, which disease was named coronavirus disease 2019 (COVID19) in February, 2020.
- Trial name
- COVID-Aging (NCT04359953)
- Testing
- Hydroxychloroquine, Azithromycin, Telmisartan
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Strasbourg, France
Post-COVID Condition, Fatigue Symptom
Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in improving severe fatigue in non-hospitalized adults with symptomatic Post-COVID Condition (PCC) (also called Long COVID).
- Trial name
- CLEAR-LC (NCT06597396)
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Beth Israel Deaconess Medical Center
Covid19
Psychological Impact, Mental Health and Sleep Disorder Among Patients Hospitalized and Health Care Workers During the 2019 Coronavirus Outbreak (COVID-19)
COVID-19 is an infectious disease caused by the last coronavirus discovered, called SARS-CoV-2. Symptoms encountered in COVID-19 are: cough, breathing difficulties (dyspnea, chest pain, etc.), pyrexia, anosmia (loss of smell)…
- Trial name
- NCT04497246
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 1,150 people
- Sponsor
- Murielle Surquin
Covid-19 Positivity Confirmed With PCR Positivity in the Nasopharyngeal Swab, Symptomatic Covid -19 Positive Patients Who Require Hospitalization
PAI-1 Levels and Predicting Covid-19 Patients' Prognosis
The primary aim of our study is to understand the effects of Covid-19 disease on vascular inflammation and coagulation cascade, and secondarily, to investigate its utility in predicting disease prognosis by analyzing serum PAI-1…
- Conditions
- Covid-19 Positivity Confirmed With PCR Positivity in the Nasopharyngeal Swab, Symptomatic Covid -19 Positive Patients Who Require Hospitalization, Patients Who Did Not Vaccinate Against Covid-19, Patients Among 20 to 90 Years of Age
- Trial name
- NCT04997928
- Testing
- Serum PAI-1 alpha analysis.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
COVID, Kidney Transplant; Complications
Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 Disease
This will be a randomized trial of maintenance versus reduction in immunosuppression in adult patients (age >18 years old) with functioning renal transplants admitted to hospital with confirmed COVID-19 disease.
- Conditions
- COVID, Kidney Transplant; Complications, Immunosuppression
- Trial name
- NCT04420364
- Testing
- Maintenance or reduction of immunosuppression
- Sponsor
- Brigham and Women's Hospital
Diabetic Patient (Type 1,2, MODY, Secondary) or With Corticosteroid-induced Diabetes Following Initiation of Corticosteroid Treatment
Tele-expertise in Patients With Diabetes Hospitalized for Covid-19 Infection
Diabetes is a major factor of morbi-mortality in Covid-19 infection. Currently, steroid therapy is required in patients under oxygen therapy. This treatment is associated with hyper glycaemia in patients with diabetes.
- Trial name
- COVIDEX (NCT04726163)
- Testing
- Continuous blind glucose measurement device (Free style Pro)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19
Minimizing the Effects of COVID-19 Hospitalization With the COVID Rehabilitation Program for the Elderly
Although evidence from the management of other viral respiratory infections suggest that early multidisciplinary rehabilitation could mitigate the adverse effects of the severe form of the illness, and reduce the length of…
- Trial name
- CORE (NCT04771052)
- Testing
- COVID Rehabilitation Program for the Elderly (CORE)
- Where
- 2 sites in Canada
- Volunteers
- 124 people
- Sponsor
- Université de Sherbrooke
COVID-19, Post-hospitalization, Disease Impact
Perceived Health After Hospitalization for COVID-19
There are currently no precise data available on the impact of COVID-19 on the daily life of patients after hospitalization. For the moment, studies have only demonstrated a strong impact of the diagnosis on the domains of…
- Trial name
- PRO-COVID (NCT04912804)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 207 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
COVID 19, Disease Outbreak
Caracteristics of the Patients Hospitalized With Unvonluntary Commitment Procedure, in the Context COVID-19
The actual worldwide context (disease outbreak, confinements instaured in many countries) is a stressful factor for many people.
- Conditions
- COVID 19, Disease Outbreak, Mental Disorders
- Trial name
- HoCoPsy (NCT04417374)
- Testing
- Description of groups caracteristics
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Montpellier
COVID-19 Pneumonia
Efficacy and Safety of Oral Immunotherapy With GcMAF in Hospitalized Patients With COVID-19 Pneumonia
As of August 16, 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for more than 21 294 000 infections and about 760 000 deaths worldwide.
- Trial name
- COral-MAF1 (NCT04845971)
- Testing
- Saisei Maf capsules
- Where
- Italy
- Volunteers
- 97 people
- Sponsor
- Dr. Spadera Lucrezia
COVID-19
Clinical Trial of Mycobacterium w in COVID-19 Positive Patients, Hospitalized But Not Critically Ill
This is a randomized, double blind, two arms, placebo controlled, clinical trial to study to evaluate the the safety and efficacy of Mycobacterium w in combination with standard of care versus placebo with standard of care for…
- Trial name
- NCT04358809
- Testing
- Suspension of heat killed (autoclaved) Mycobacterium w
- Where
- 4 sites in India
- Volunteers
- 480 people
- Sponsor
- Cadila Pharnmaceuticals
Corona Virus Infection
Feasibility of a Self-guided Exercise Program Among Hospitalized COVID-19 Patients
The investigators' aim is to conduct a study looking into safety and feasibility study of Covid patients participating in a self-guided exercises program while admitted to the hospital.
- Trial name
- NCT04821531
- Testing
- PT Pal, Exercise Manual
- Where
- United States
- Sponsor
- Montefiore Medical Center
Coronavirus Infections
Arrhythmic Manifestations and Management in Hospitalized COVID-19 Patients
Although arrhythmias appear to be common in COVID-19 patients, arrhythmia mechanisms and characteristics, predisposing factors, incidence of sudden cardiac death and predictors, therapeutic strategies employed as well as long…
- Trial name
- NCT04465552
- Testing
- Patients received standard of care treatment during hospitalization
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Ischemic Stroke
Laser Acupuncture Improves Constipation in Patients Hospitalized for Stroke During the COVID-19 Pandemic
With the aging of today's population, stroke is the top three causes of disability and death among people over the age of 60 in the world.
- Trial name
- NCT05002348
- Testing
- Laser acupoint stimulation(Laser pen)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yueh-Lin Hsu
COVID-19
Tocilizumab Versus Baricitinib in Patients With Severe COVID-19
The aim of this study is to investigate whether baricitinib is non-inferior to tocilizumab in severe COVID-19.
- Trial name
- NCT05082714
- Testing
- Tocilizumab, Baricitinib
- Where
- Greece
- Volunteers
- 251 people
- Sponsor
- University Hospital of Patras
COVID-19, Sars-CoV2
Effects of COVID-19 Convalescent Plasma (CCP) on Coronavirus-associated Complications in Hospitalized Patients
The purpose of this study assess the efficacy and safety of anti-SARS-CoV-2 convalescent plasma in hospitalized patients with acute respiratory symptoms up to 14 days after the onset of initial symptoms.
- Trial name
- CAPRI (NCT04421404)
- Testing
- COVID-19 Convalescent Plasma (CCP)
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- Priscilla Hsue, MD
Intensive Care Unit, SARS-CoV2
Assessment of SARS-CoV-2 Effect on Post-traumatic Stress of Patients Hospitalized in Intensive Care Unit
Patients admitted to the intensive care unit develop psychiatric disorders, such as anxiety, depression or post-traumatic stress disorder, which can be prolonged.
- Trial name
- FAMILY-COVID (NCT04872049)
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Phase II Safety Single-arm Study of CDK4/6 Inhibition With Palbociclib in Hospitalized, Moderate COVID-19 Cases to Prevent Thromboinflammation
This is a one-site, interventional, prospective, single-arm, open-label, controlled phase-IIa trial evaluating the safety and efficacy of palbociclib in hospitalized, moderate COVID- 19 cases.
- Trial name
- CDK6COV (NCT05371275)
- Testing
- Palbociclib
- Where
- Germany
- Sponsor
- biotx.ai GmbH
COVID-19
Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19
Blinded, multicenter, placebo-controlled, randomized clinical trial evaluating lopinavir/ritonavir vs placebo in early outpatient treatment of adults with COVID-19
- Trial name
- TREATNOW (NCT04372628)
- Testing
- Lopinavir/Ritonavir 400 mg/100 mg
- Where
- 6 sites in United States
- Volunteers
- 452 people
- Sponsor
- Vanderbilt University Medical Center
COVID-19
Asunercept for the Treatment of Patients With Moderate to Severe COVID-19 Disease
This clincial trial is a prospective, multicenter, randomized, double-blind, placebo-controlled Phase III trial in hospitalized patients with moderate to severe COVID-19 corresponding to score 5 or 6 on the WHO 10-point clinical…
- Trial name
- ASUCOV (NCT05639192)
- Testing
- Asunercept
- Where
- 39 sites in Austria, France and 7 more
- Volunteers
- 34 people
- Sponsor
- Apogenix GmbH