Clinical trials: Hospitalized COVID-19
Covid19
Efficacy and Safety Evaluation of Inhaleen Inhalation in Hospitalized COVID-19 Patients
The current study will investigate the tolerability and efficacy of inhaled Carragelose® versus saline in hospitalized COVID-19 patients.
- Trial name
- NCT04793984
- Testing
- Carragelose, NaCl
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Marinomed Biotech AG
SARS-CoV 2
Muscle Mass and Strength as Predictors of Time to Discharge in Patients With COVID-19
The severe acute respiratory syndrome induced by the new coronavirus (SARS-CoV-2) has been declared a worldwide pandemic. Identifying common characteristics of the disease is crucial to promote a better prognosis for patients and…
- Trial name
- NCT04406233
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- University of Sao Paulo
Covid19, Thrombosis
Hemostatic Profile in Patients Affected by COVID-19
Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has been associated with the occurrence of cardiovascular adverse events including acute…
- Trial name
- EMO-COVID (NCT04595110)
- Testing
- Observational study
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- ANNA FALANGA
COVID-19 Pneumonia
Azithromycin+Amoxicillin/Clavulanate vs Amoxicillin/Clavulanate in COVID19 Patients With Pneumonia in Non-intensive Unit
The global pandemic of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Wuhan, China, in December 2019, and has since spread worldwide.1 As of April 14…
- Trial name
- AziA (NCT04363060)
- Testing
- Azithromycin with amoxicillin/clavulanate, amoxicillin/clavulanate
- Where
- 3 sites in France
- Volunteers
- 104 people
- Sponsor
- Nantes University Hospital
COVID-19
A Study of Efficacy and Safety of Azvudine vs. Nirmatrelvir-Ritonavir in the Treatment of COVID-19 Infection
The COVID-19 pandemic has become a major public health challenge, and the treatment options for the disease are currently limited.
- Trial name
- NCT05697055
- Testing
- Azvudine, Nirmatrelvir-Ritonavir
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Shandong Provincial Hospital
COVID-19, Mental Health Impairment
A Study on a Digital Platform for COVID19+ Patients, Designed to Facilitate Communication and Mental-health Care During and After Hospitalization.
This study presents a digital mental-health protocol designed to offer remote, personalized support to former or current COVID-19 patients. A total of 100 subjects will be enrolled.
- Conditions
- COVID-19, Mental Health Impairment, Telemedicine
- Trial name
- DigiCOVID (NCT05231018)
- Testing
- Psychotherapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
COVID-19
Trial of Imatinib for Hospitalized Adults With COVID-19
This study is a randomized Double-Blind Placebo-Controlled Trial on the Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19
- Trial name
- NCT04394416
- Testing
- Imatinib
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Maryland, Baltimore
COVID-19
Adaptive COVID-19 Treatment Trial 4 (ACTT-4)
ACTT-4 will evaluate the combination of baricitinib and remdesivir compared to dexamethasone and remdesivir. Subjects will be assessed daily while hospitalized.
- Trial name
- NCT04640168
- Testing
- Baricitinib, Dexamethasone, Remdesivir
- Where
- 72 sites in United States, Japan and 3 more
- Volunteers
- 1,010 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID19, Ophthalmopathy
Ocular Sequelae of Patients Hospitalized for Respiratory Failure During the COVID-19 Epidemic
Ophthalmologic damages secondary to COVID-19 coronavirus infection are little described. The ocular involvement is probably multiple, ranging from pathologies of the anterior segment such as conjunctivitis and anterior uveitis to…
- Trial name
- SOCOVID (NCT04387292)
- Testing
- Ophthalmologic exam
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Corona Virus Infection
Cytopenias in Hospitalized Patients of Corona Virus Infection(COVID-19) During First and Other Waves
Demographic, Clinical and laboratory data as well as outcome of total 202 COVID-19 patients who were Polymerase Chain Reaction (PCR) positive and admitted in Fatima memorial Hospital, Lahore, Pakistan, was collected during first…
- Trial name
- NCT05258812
- Where
- Pakistan
- Volunteers
- 202 people
- Sponsor
- Fatima Memorial Hospital
Oximetry, Covid19
Feasibility and Impact of Remote Oximetry in Patients Hospitalized With Covid-19
The objective of MoxiCov is to monitor the oximetry of patients admitted to the Covid nursery to provide a more detailed assistance expecting to reduce the amount of hypoxia in these patients.
- Trial name
- MoxiCov (NCT04587921)
- Testing
- Digital oximeter monitoring
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
COVID-19
Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19
Phase 2: The primary objective of the study is to evaluate the clinical efficacy of sarilumab relative to the control arm in adult patients hospitalized with COVID-19 regardless of disease severity strata.
- Trial name
- NCT04315298
- Testing
- Sarilumab
- Where
- 62 sites in United States
- Volunteers
- 1,912 people
- Sponsor
- Regeneron Pharmaceuticals
Acute Respiratory Distress Syndrome, Covid19
Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19
Acute myocardial injury has been a finding of variable frequency among patients diagnosed with COVID-19. It is now recognized that cTnI levels are strongly associated with increased mortality.
- Conditions
- Acute Respiratory Distress Syndrome, Covid19, Myocardial Injury
- Trial name
- PREMIER (NCT04760821)
- Testing
- Trimetazidine
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Ministry of Health, Brazil
COVID-19
Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19.
CALAVI will investigate the safety, efficacy and pharmacokinetics of acalabrutinib together with Best Supportive Care in the treatment of COVID-19.
- Trial name
- CALAVI (NCT04346199)
- Testing
- Acalabrutinib
- Where
- 50 sites in Argentina, Brazil and 12 more
- Volunteers
- 177 people
- Sponsor
- AstraZeneca
Quality of Life, Long-term Outcomes
Quality of Life and Long-term Outcomes After Hospitalization for COVID-19
The present study aims to assess the determinants of health-related quality of life and long-term outcomes among survivors of hospitalization for Covid-19 in Brazil.
- Conditions
- Quality of Life, Long-term Outcomes, Coronavirus Infection
- Trial name
- NCT04376658
- Testing
- COVID-19 Severity
- Where
- Brazil
- Volunteers
- 1,508 people
- Sponsor
- Hospital Moinhos de Vento
Coronavirus Disease 2019 (COVID-19), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
COVID-19 and Anti-CD14 Treatment Trial
This study aims to address the following objectives: 1. To determine the efficacy of IC14, an anti-CD14 chimeric monoclonal antibody, in patients hospitalized with respiratory disease and hypoxemia due to SARS-CoV-2, in terms of…
- Trial name
- CaTT (NCT04391309)
- Testing
- anti-CD14, remdesivir
- Where
- 5 sites in United States
- Volunteers
- 49 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coronavirus Disease 2019
Fostamatinib for Hospitalized Adults With COVID-19
Background: COVID-19 is a new disease caused by SARS-CoV-2 that was identified in 2019. Some people who get sick with COVID-19 become ill requiring hospitalization. There are some medicines that may help with recovery.
- Trial name
- NCT04579393
- Testing
- fostamatinib
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pneumonia, Viral
Efficacy, Safety, Tolerability, and Biomarkers of Ibudilast (MN-166) in Patients Hospitalized With COVID-19 at Risk for ARDS
The goal of this study is to evaluate the effects of Ibudilast (MN-166) versus placebo in hospitalized patients infected with COVID-19 at risk for developing acute respiratory distress syndrome (ARDS) receiving standard of care…
- Trial name
- NCT04429555
- Testing
- Ibudilast
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- MediciNova
Covid19
Mental Status and Quality of Life of Post-COVID-19 Patients
The current SARS-CoV-2 virus pandemic has already affected the lives of every person on earth. Most of the information given in the media on a daily basis focuses on the pandemic aspects.
- Trial name
- NCT04949035
- Testing
- Assessment of mental state and quality of life
- Where
- Poland
- Volunteers
- 147 people
- Sponsor
- The Opole University of Technology
SARS-CoV, Nutrition Disorders
Nutritional Assessment of Hospitalized Patients With COVID-19
The nutritional consequences of the infection by the SARS-CoV-2 are as follows: A severe respiratory infection induces an inflammatory syndrome and hypercatabolism, as well as an increase in energy expenditure related to…
- Trial name
- DenutCOVID (NCT04503525)
- Testing
- Nutritional assessment
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Lille Catholic University