Clinical trials: Host Disease Manifestation
Chronic Low-back Pain
The Effectiveness of Kinesio Taping in Patients With Chronic Low Back Pain
The objective of this study is to determine the effectiveness of Kinesio taping (KT) with Conventional Physical therapy (CPT) - Transcutaneous Electrical Nerve Stimulation (TENS) and Supervised Exercise therapy and CPT in the…
- Trial name
- NCT05173948
- Testing
- Kinesio taping, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- University of Tabuk
Neck Pain
Electroacupuncture for Chronic Neck Pain
Objective: The primary objective of this study is to evaluate the long-term efficacy of electroacupuncture for chronic neck pain. The secondary objective is to document any possible side effects of acupuncture.
- Trial name
- NCT00826215
- Testing
- electroacupuncture
- Volunteers
- 200 people
- Sponsor
- Hong Kong Baptist University
Migraine
Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)
The purpose of this study is to determine whether a painless and noninvasive procedure called Transcranial Direct Current Stimulation (tDCS) can be an effective therapy for the treatment of migraine and migraine-associated pain.
- Trial name
- NCT00521196
- Testing
- DC Stimulator (Transcranial Direct Current Stimulator)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Beth Israel Deaconess Medical Center
Chronic Postoperative Pain
Data Collection for Prediction of Postoperative Chronic Pain for a Software
Postoperative Persistent Pain (PPP) is reported with a high incidence in adults 11.5-47%. This high incidence effects quality of life of patients causes social-economical problems and arises medico-legal issues.
- Trial name
- NCT02190682
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 733 people
- Sponsor
- Istanbul University
Spinal Cord Injuries, Tetraplegia, Unspecified, Incomplete, Chronic
Improving Hand Recovery With Neuromodulation in Tetraplegia
This study will examine a form of non-invasive brain stimulation applied with intensive therapy of the arm and hand. The goal of the study is to determine if arm and hand function can be improved in people with incomplete…
- Trial name
- IGNITE (NCT03954496)
- Testing
- transcranial direct current stimulation, Intensive upper extremity motor training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Sara Shahid Salles
Low Back Pain
Limiting Trunk Flexion as a Self-treatment for Low Back Pain
The purpose of the proposed study is to test the effect of an intervention technique that reduces trunk flexion upon rising, on the outcome measures of self-reported back pain and functional impairment in individuals with chronic…
- Trial name
- RST (NCT01830751)
- Testing
- Restrained Sitting Treatment
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Chronic Low Back Pain
Identification of Prognostic Indicators for Rehabilitation in Chronic Nonspecific Low Back Pain Patients
There is a consensus that exercise therapy should be used as a therapy approach in CLBP but little consensus has been reached about the preferential type of therapy.
- Trial name
- NCT02063503
- Testing
- physiotherapy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universiteit Antwerpen
Post-Surgical Pain, Chronic, Post-traumatic Pain, Chronic
Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation
This research aims to uncover the Mechanisms of pain relief through the FDA-cleared peripheral transcutaneous magnetic stimulation (pTMS) device by MagVenture.
- Trial name
- NCT07199361
- Testing
- Peripheral Transcutaneous Magnetic Stimulation from MagVenture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida International University
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Tourette Syndrome, Tic Disorders
Evaluating and Promoting Resilience in Adolescents With Tourette Syndrome
This study adapts and tests PRISM (Promoting Resilience in Stress Management), a short skills-based program that teaches resilience, for teens ages 12-18 with Tourette syndrome or persistent tic disorder.
- Conditions
- Tourette Syndrome, Tic Disorders, Persistent (Chronic) Motor or Vocal Tic Disorder
- Trial name
- PRISM-TS (NCT07905898)
- Testing
- PRISM Intervention, Usual care intervention
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Wake Forest University Health Sciences
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Systemic Juvenile Idiopathic Arthritis (SJIA)
ß-SPECIFIC 4 Patients: Study of Pediatric EffiCacy and Safety wIth FIrst-line Use of Canakinumab
The purpose of this study was to evaluate the efficacy observed with canakinumab dose reduction in a subgroup of patients in the extension study CACZ885G2301E1.
- Trial name
- ß-SPECIFIC 4 (NCT02296424)
- Testing
- ACZ885 150 mg (Canakinumab)
- Where
- 50 sites in United States, Austria and 14 more
- Volunteers
- 182 people
- Sponsor
- Novartis Pharmaceuticals
Low Back Pain
Measurement of Substance P in Saliva of Low Back Pain Patients
The purpose of this study is to compare the levels of Substance P in saliva, in patients with severe chronic low back pain and in subjects without it.
- Trial name
- NCT00735735
- Testing
- The taking of a saliva sample from each subject.
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kovacs Foundation
Psoriasis, Cutaneous T Cell Lymphoma
Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases
The molecular mechanisms of action of photo(chemo)therapy in skin diseases are investigated in this study. The phototherapeutic modalities employed include UVB (ultraviolet B), UVA (ultraviolet A), PUVA (psoralen+UVA) and/or…
- Conditions
- Psoriasis, Cutaneous T Cell Lymphoma, Lymphoproliferative Disorders, Eczema
- Trial name
- BioUV2017 (NCT03340155)
- Testing
- Photo(chemo)therapy
- Where
- Austria
- Volunteers
- 240 people
- Sponsor
- Medical University of Graz
Autogenous Bone Grafts
Effect of Local Administration of Morphine for Analgesia After Iliac Bone Graft Harvest
The goal of the current study was to evaluate the analgesic efficacy of low-dose morphine administered to the site of bone graft harvesting in patients undergoing orthopedic surgery.
- Trial name
- NCT01037335
- Testing
- morphine
- Sponsor
- The Cleveland Clinic
Graft vs Host Disease, Oral Manifestations
Clinical Trial With Clobetasol and Dexamethasone for Topical Treatment of Oral Lesions of Chronic Graft-versus-host Disease
The purpose of this study is to perform a randomized, double-blind, clinical trial comparing the topical treatment with clobetasol or dexamethasone for symptomatic oral lesions of chronic graft-versus-host disease.
- Trial name
- NCT01699412
- Testing
- Clobetasol, Dexamethasone
- Where
- 2 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- Grupo de Estudos Multicentricos em Onco-Hematologia
Chronic Kidney Disease Stage 2, Chronic Kidney Disease Stage 3
Preserving Kidney Function in Children With Chronic Kidney Disease
Pediatric chronic kidney disease (CKD) results from health conditions that reduce kidney function for >3 months. It can progress to end-stage kidney disease (ESKD), which requires dialysis or kidney transplant.
- Conditions
- Chronic Kidney Disease Stage 2, Chronic Kidney Disease Stage 3, Pediatric Kidney Disease
- Trial name
- PRESERVE (NCT05169411)
- Testing
- Blood pressure, Urine protein
- Where
- United States
- Volunteers
- 20,240 people
- Sponsor
- Children's Hospital of Philadelphia
Neck Pain, Cervical Pain
The Effect of Cervical Taping on Neck Pain and Kinematics in Patients With Chronic Neck Pain
Objective: This study examined the effects of elastic tape applied to the neck on patients experiencing chronic neck pain. Background: Neck pain is often persistent or recurrent.
- Conditions
- Neck Pain, Cervical Pain, Chronic Pain
- Trial name
- NCT02915887
- Testing
- Cervical Taping
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- University of Haifa
Spinal Cord Injuries (SCI), Spinal Cord Injury, Chronic
BCI-Assisted SCS-EXS for Gait Optimization
The goal of this clinical trial is to evaluate the safety and technical feasibility of a novel brain-machine interface (BCI)-assisted spinal cord stimulation (SCS) and exoskeleton (EXS) system in patients with spinal cord injury…
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Chronic, Spinal Cord Injury, Spinal Cord Injury Cervical
- Trial name
- BASEGO (NCT06939660)
- Testing
- BCI-SCS-EXS
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Xuanwu Hospital, Beijing
Traumatic Encephalopathies, Chronic, Concussion, Mild
Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries
Concussion is the most common type of brain injury throughout life. Study is seeking improvement of long-term residua following adolescent and adult post-traumatic injuries often associated with contact sports and accidental…
- Conditions
- Traumatic Encephalopathies, Chronic, Concussion, Mild, Concussion, Intermediate, Concussion, Severe
- Trial name
- C-TBI (NCT02959294)
- Testing
- Microcannula Harvest Adipose, Centricyte 1000, Sterile Normal Saline IV deployment AD-cSVF
- Where
- United States
- Sponsor
- Robert W. Alexander, MD, FICS