Clinical trials: Human Factors
IVF, Infertility
Human Follicular Fluid Markers and Reproductive Outcomes in IVF
The goal of this observational study is to understand the processes in the growing follicles development in more detail and to improve In Vitro Fertilisation (IVF) treatments.
- Trial name
- NCT05893238
- Testing
- Natural cycle In Vitro Fertilisation (IVF), Blood samples for analysis, Follicular fluid for analysis
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Janna Pape
Cardiac Arrest
The Association Between Technical and Non-technical Skills in Real-life ALS Situations. Impact of Pit Crew Model on the Resuscitation Skills.
Cardiac arrest is handled by cardiopulmonary resuscitation which is a time critical emergency situation. The actions during resuscitation are lead by international guidelines.
- Trial name
- NCT03017144
- Testing
- Pit crew model education
- Volunteers
- 36 people
- Sponsor
- Turku University Hospital
Chronic Hepatitis b, Non-alcoholic Fatty Liver Disease
Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD
Chronic hepatitis B (CHB) affects an estimated 292 million people, and causes approximately 800,000 people deaths per year from liver-related complications including cirrhosis and hepatocellular carcinoma, remaining a major…
- Trial name
- NCT05766449
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Advanced/Metastatic Solid Tumors, Colorectal Cancer
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
This is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent in patients with mCRC.
- Conditions
- Advanced/Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer
- Trial name
- NCT03526835
- Testing
- MCLA-158, MCLA-158 + Pembrolizumab, MCLA-158 + FOLFIRI
- Where
- 54 sites in United States, Belgium and 5 more
- Volunteers
- 560 people
- Sponsor
- Merus B.V.
Smoking Cessation, Smoking, Tobacco
Pivot Breath Sensor Human Factors and Usability Study
Prospective, observational open label, single center study enrolling up to 15 subjects to evaluate human factors and usability of the Pivot Breath Sensor.
- Trial name
- NCT03835260
- Testing
- Pivot Breath Sensor
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Jennifer Marler, MD
Laparoscopic Gynecological Surgery
Human Factors Actual-Use Clinical Protocol
The purpose of this study is to confirm device use safety and effectiveness of the Eximis CS (Contained Segmentation) System in actual use by representative users, use, and use environments as required for regulatory agency…
- Trial name
- CONTAIN (NCT04799210)
- Testing
- Eximis CS (Contained Segmentation) System
- Where
- 7 sites in United States
- Volunteers
- 3 people
- Sponsor
- Eximis Surgical
Healthy Volunteers
A Double-blind Randomized Placebo-controlled Study Study of the Safety, Reactogenicity and Immunogenicity of the GamFluVac
The aim of the present study is at the first stage: a comparative assessment of the safety of the two methods of vaccine administration, at the second - an assessment of the safety and state of post-vaccination immunity at…
- Trial name
- NCT04034290
- Testing
- GamFluVac
- Where
- Russia
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Type 2 Diabetes
Maximising the Taste and Health Value of Plant Food Products
To investigate if a high dietary intake of bitter and strong tasting vegetables have positive health effects (insulin sensitivity, glucose tolerance, central obesity, fasting and postprandial lipid profile, blood pressure…
- Trial name
- MAXVEG (NCT01397942)
- Testing
- Diet intervention
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- Aarhus University Hospital
Corneal Transplant Rejection
Risk Factors for Human Corneal Graft Failure : a Monocentric Retrospective Observational Cohort
Keratoplasty is one of the most common grafts and penetrating keratoplasty is still the technique most used in the world, ahead of lamellar grafts, and is estimated to represent 70% of the total.
- Trial name
- NCT04791696
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Infertility, Male, Infertility
Measuring Free Radicals in Human Sperm Cells Related to Microbiota and Lifestyle Factors
The cause of infertility can be due to a female factor or a male factor. In case of a male factor, it is often due to poor semen quality. However, the cause of poor quality is often unknown.
- Trial name
- SIRIUS (NCT05514223)
- Testing
- Biomaterial collection for observational purpose
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- University Medical Center Groningen
Pregnant Women
Placental Transfer of Tenofovir
The purposes of this study are to determine whether transporters expression levels and drug interaction between TDF and FTC could contribute to modulate the placental transfer of this drug or.
- Trial name
- TDF-PTP (NCT02020083)
- Where
- France
- Volunteers
- 369 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris