Clinical trials: Human Papilloma Virus (HPV)
Cervical Intraepithelial Neoplasia
Human Papillomavirus (HPV) Testing to Improve Cervical Cancer Screening in the Mississippi Delta
Background: Cancer of the cervix (bottom third of the uterus, or womb) can be prevented by regular Pap tests (also called Pap smears), which check for changes in the cells of the cervix.
- Trial name
- NCT00443313
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- National Cancer Institute (NCI)
Papilloma Viral Infection
Immunogenicity of Off-Schedule Dosing of HPV Vaccine
The purpose of this study is to gain a better understanding of the body's response to a human papillomavirus (HPV) (sexually transmitted disease), vaccine and booster shot.
- Trial name
- NCT01030562
- Where
- 7 sites in United States
- Volunteers
- 1,321 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cervical Cancers, CIN - Cervical Intraepithelial Neoplasia
Primary HPV Self-Collection in Indonesia
The purpose of this study is to implement human papillomavirus (HPV) self-collection in Indonesia.
- Conditions
- Cervical Cancers, CIN - Cervical Intraepithelial Neoplasia, Human Papillomavirus (HPV)
- Trial name
- NCT06942286
- Testing
- HPV Self-Collection
- Where
- 3 sites in Indonesia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Dharmais National Cancer Center Hospital
Cervical Intraepithelial Neoplasia
Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device
The purpose of this academic-industrial partnership will be to compare two thermoablation modalities using devices adapted to low and middle income countries (LMICs) to traditional CO2-based cryotherapy for the treatment of…
- Trial name
- NCT03429582
- Testing
- Standard C02 Cryotherapy, Single Tip Thermoablation, Multiple Tip Thermoablation
- Where
- 2 sites in China, El Salvador
- Volunteers
- 1,154 people
- Sponsor
- The Cleveland Clinic
Human Papilloma Virus
Developing and Evaluating a Novel Approach to Improve HPV Vaccination Coverage Among High-risk, Under-immunized Adults Via the Emergency Department
To determine if the emergency department (ED) setting offers a viable space for improving HPV vaccination coverage among 18 to 45-year-old adults who have not yet received human papilloma virus (HPV) vaccination or who did not…
- Trial name
- NCT06229353
- Testing
- Gardasil 9
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Anal High-grade Squamous Intraepithelial Lesion
Anal HSIL Screening Algorithm
This the propose to use the Multiphase Optimization Strategy Trial (MOST) design to identify an anal HSIL screening algorithm which is most suitable in terms of effectiveness, efficiency, and economy.
- Trial name
- 0007/65 (NCT05531799)
- Testing
- OPTIMIZATION PHASE
- Where
- Thailand
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
HPV Infections
A Phase 1 Study of PV-001 9-valent Human Papillomavirus(HPV) Vaccine
Study Title: Evaluation of the Safety and Immunogenicity of a Third Dose of PV-001 in Healthy Women Aged 19-45 Objective: To assess the safety and antibody response of a third dose of PV-001 in healthy adult female participants.
- Trial name
- HPV (NCT07081334)
- Testing
- PV-001, PEV-001
- Where
- South Korea
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- POSVAX
Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18
Development of a Self-collection Device for Cervical Cancer Screening
Evaluation of a novel self-collection device for cervical cancer screening.
- Conditions
- Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18, Human Papilloma Virus
- Trial name
- NCT05669911
- Testing
- Teal Health Self-Collection Device Group
- Where
- 6 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Teal Health, Inc.
Human Papilloma Virus Related Cervical Carcinoma
The Women's Screening and Self-Testing Program (PROMETA) Study
This proposal directly addresses the ability to safely scale-up a Screen-Triage-Treat approach to cervical cancer screening. The investigators propose to capitalize on a pool of screen-eligible women accessing routine care within…
- Trial name
- PROMETA (NCT06810739)
- Testing
- HPV DNA testing be self-collected vaginal swab
- Where
- Mozambique
- Volunteers
- 8,445 people
- Sponsor
- Tulane University
Cervical Cancer
Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls
The aims of this study are: 1. To determine feasibility of a school-based human papillomavirus (HPV) vaccination programme in Tanzania. 2.
- Trial name
- NCT01173900
- Testing
- Gardasil® HPV vaccine
- Where
- Tanzania
- Volunteers
- 5,532 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Human Papillomavirus Vaccines
Developing a Self-persuasion Intervention Promoting Adolescent HPV Vaccination
HPV vaccine coverage among adolescents in the US is suboptimal. This is particularly true among traditionally underserved adolescents. Few parent-targeted interventions have focused on the parental decision-making process.
- Trial name
- NCT02537756
- Testing
- Project Voice
- Where
- United States
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cervix, Dysplasia, HPV Infection
Retrospective Cohort Study of the Effectiveness of the Prophylactic Vaccine Against the Human Papilloma Virus in the Prevention of Recurrence in Women Who Have Received an Excisional Therapy by HSIL / CIN.
A retrospective cohort study of women treated by excisional therapy due to HSIL/ CIN at Clínico San Carlos Hospital between 2012-2018.
- Conditions
- Cervix, Dysplasia, HPV Infection, HPV Vaccine, Cervix Lesion
- Trial name
- VENUS (NCT04171505)
- Testing
- HPV vaccine
- Where
- Spain
- Volunteers
- 508 people
- Sponsor
- Hospital San Carlos, Madrid
Incident HPV16, 18, 31, 33, 45, 52 or 58 Infection
Vaccine Effectiveness of One Dose of the Nonavalent Human Papillomavirus (HPV) Vaccine Among Young-adult Women in Sweden Among Women Participating in a Clinical Trial of Concomitant HPV Vaccination and Screening
This study aims to evaluate the vaccine effectiveness of 1 dose the nonavalent human papillomavirus (HPV) vaccine against HPV16, 18, 31, 33, 45, 52, and 58 infection among young adult women in Sweden participating in a nationwide…
- Trial name
- FASTER1DOSE (NCT07314307)
- Testing
- Gardasil 9 2 dose regimen
- Where
- Sweden
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Solid Organ Transplant Recipient, Skin Cancer
The Organ Transplant Recipient HPV and Skin Cancer Study
Solid organ transplant recipients (OTRs) receive lifelong immunosuppressive therapy, which puts them at increased risk of cutaneous and mucosal cancers.
- Conditions
- Solid Organ Transplant Recipient, Skin Cancer, Skin Dysplasia, HPV Infection
- Trial name
- NCT05284877
- Testing
- No intervention
- Where
- 3 sites in Denmark
- Volunteers
- 1,500 people
- Sponsor
- Merete Haedersdal
HPV, Immunization
HPV Vaccination Study in Postpartum Women
The human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the United States (U.S.) and is responsible for a wide range of conditions, including cancers within the anogenital tract and the…
- Conditions
- HPV, Immunization, Human Papilloma Virus
- Trial name
- PPV (NCT04274153)
- Testing
- Gardasil9
- Where
- 2 sites in United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Human Papillomavirus Infection
Comparison of Self-collection Using Dry Compared to Wet Swabs for HPV Detection
This study will compare the performance of self-collected vaginal swabs, transported without liquid media (dry swabs) and self-collected vaginal swabs, transported in liquid media (wet swabs) for detection of hrHPV DNA LBC as the…
- Trial name
- HPV (NCT06213051)
- Testing
- • COPAN Self-collection FLOQSwabs® (COPAN, Italy)
- Where
- Kenya
- Volunteers
- 1,306 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Genital Warts, Human Papilloma Virus
Typing of Human Papilloma Virus (HPV) From Female Genital Warts
This is a longitudinal observational study of women presenting to Groote Schuur Hospital with genital warts. The study will evaluate the socio-demographic characteristics of the women using a structured questionnaire.
- Trial name
- NCT01192282
- Testing
- Medical / Surgical Treatment
- Where
- South Africa
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Cervical Adenocarcinoma, Human Papillomavirus
HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
This study aims to analyze the multi-omics results between uterine cervical adenocarcinoma patients with and without human papillomavirus (HPV) infections.
- Conditions
- Cervical Adenocarcinoma, Human Papillomavirus, Genome-wide Association Study, Whole Exome Sequencing
- Trial name
- NCT03742869
- Testing
- A multi-omics analysis
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Lei Li
Paediatric Kidney or Liver Transplantation, Chronic Kidney Disease
Prevention of Human Papillomavirus (HPV) Infection in Paediatric Kidney and Liver Transplant Recipients and in Paediatric Patients With Advanced Chronic Kidney Disease
Due to their immunosuppressive therapy, solid-organ transplant (SOT) recipients bear a 10 to 100 times higher risk of human papillomavirus (HPV)-associated malignancies than healthy individuals.
- Trial name
- NCT03100682
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- University Hospital Heidelberg
HIV Infections, HPV Infection
Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique
Given that WLWH are more likely to develop persistent HPV infection and CC, effective screening and the management and treatment of pre-cancerous cervical abnormalities is critical to decrease the global burden of cervical…
- Conditions
- HIV Infections, HPV Infection, CIN 2/3
- Trial name
- NCT06326294
- Testing
- Thermal ablation, LOOP ELECTROSURGICAL EXCISION PROCEDURE
- Where
- Mozambique
- Volunteers
- 4,844 people
- Sponsor
- Instituto Nacional de Saúde, Mozambique
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