Clinical trials: Hyaluronic Acid
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Immediate Implant Placement
Immediate Implant Placement Using Xenograft Mixed with Vitamin D Versus Hyaluronic Acid.
Immediate implant placement using xenograft as space filling material mixed with vitamin D versus hyaluronic acid in posterior mandible region This study aims to evaluate implant stability and density after placement of immediate…
- Trial name
- NCT06842368
- Testing
- Hyaluronic Acid (HA), Vitamin D
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Loss, Bone Lesion
Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration
Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.
- Trial name
- NCT05957926
- Testing
- hyaluronic acid added to hydroxyapetite, Hydroxyapatite alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy, High Risk
Use of Dietary Supplements in Patients at Risk of Abortion Treated With Progesterone.
The trial aims to investigate the effect of supplementation with hyaluronic acid, alpha-lipoic acid, magnesium, vitamin D and vitamin B6 in progesterone-treated pregnant women with risk factors for abortion.
- Trial name
- NCT04874285
- Testing
- HA
- Where
- Italy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
Tissue Adhesion, Gynecologic Surgery
The Assessment of the Use of Anti-Adhesion Agents to Prevent Pelvic Postoperative Adhesions
The aim of this study is to assess the safety and effectiveness of PROTAHERE Absorbable Adhesion Barrier to prevent pelvic postoperative adhesions.
- Trial name
- NCT04063085
- Testing
- PROTAHERE Absorbable Adhesion Barrier, Hyalobarrier Gel, No treatment
- Where
- Taiwan
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Hyaluronic Acid, Gingival Recession, Localized
Hyaluronic Acid and Free Gingival Graft Healing
This study aims to evaluate the impact of locally applied hyaluronic acid on free gingival graft wound bed healing and palatal donor site wound healing. Forty subjects will be randomly divided in two separate groups.
- Conditions
- Hyaluronic Acid, Gingival Recession, Localized, Pain, Postoperative
- Trial name
- NCT05990049
- Testing
- Hyadent BG
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Socket Preservation
Sticky Bone vs Xenograft With Cross-linked Hyaluronic Acid in Socket Preservation
The present study aimed to evaluate clinical and radiographic outcomes of sticky bone in comparison to crosslinked hyaluronic acid mixed with xenograft in alveolar ridge preservation.
- Trial name
- NCT06983015
- Testing
- sticky bone, xenograft mixed with cross-linked hyaluronic acid
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Aging, Pain
RHA® Redensity With New Anesthetic Agent - Perioral Rhytids
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT04069585
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Dermal Filler
Safety and Efficacy of the HA-based Dermal Fillers HYAcorp Lips and Face
Purpose of this study is the demonstration of safety and efficacy of the dermal fillers HYAcorp Lips and HYAcorp Face for restoration of the facial volume and contour.
- Trial name
- PMCF_HYAcorp (NCT04546516)
- Testing
- HYAcorp Lips and HYAcorp Face
- Where
- 2 sites in Germany
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- BioSCIENCE GmbH
Aging
Changing in Skin Physiology After Microdroplet Placement of Stabilized Hyaluronic Acid in Aging Faces
IMPORTANCE Skin rejuvenation can be achieved effectively and safely by injection of a stabilized hyaluronic acid (HA)-based gel of nonanimal origin (NASHA) injection using a stamp-type electronic multineedle injector.
- Trial name
- NCT02312154
- Testing
- Restylane Vital
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Konkuk University Hospital
Hyaluronic Acid, Fat Graft
Clinical Evaluation of Interdental Papilla Reconstruction Using Injectable Autogenous Fat Versus Hyaluronic Acid Filler.
The goal of this randomized controlled trial is to evaluate the amount of interdental papilla fill following the injection of the fat graft compared to hyaluronic acid filler in patients with interdental papilla deficiency.
- Trial name
- NCT05579522
- Testing
- Fat graft injection, Hyaluronic acid injection
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nasolabial Fold, Safety
A Study to Evaluate the Performance and Safety of GP0045 for Correction of Moderate to Severe Nasolabial Folds
This is a study to assess the performance and safety of GP0045 when injected in the nasolabial folds. There is an 18 months follow up period.
- Trial name
- NCT03300466
- Testing
- GP0045, Comparator
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Cheek Augmentation, Correction of Age-related Midface Contour Deficiencies
RHA®4 for Midface Volume Deficiency
This is a prospective, randomized, controlled, blinded evaluator, multicenter, between subjects clinical study to identify whether RHA4 is non-inferior to a comparator device for treatment of midface volume deficiency 8 weeks…
- Trial name
- NCT05133739
- Testing
- injection of RHA®4 in Midface, injection of Comparator Product in Midface
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Healthy Japanese Subjects
The Effect of Oral Hyaluronic Acid on the Skin
This clinical trial aims to clarify the effect of hyaluronic acid on skin conditions.
- Trial name
- NCT05803083
- Testing
- Hyaluronic acid 75 mg/capsule, Hyaluronic acid 50 mg/capsule
- Where
- Japan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bloomage Biotechnology Corp., Ltd.
Healthy Japanese Subjects
The Effect of Oral Hyaluronic Acid (UltraHA®) on the Knee Function
This clinical trial aims to clarify the effect of UltraHA® on knee joint conditions.
- Trial name
- NCT05683327
- Testing
- UltraHA® 75 mg/capsule, UltraHA® 40 mg/capsule
- Where
- 2 sites in Japan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Orthomedico Inc.
Infra-orbital Hollows, Tear-trough Deformity
RHA® Redensity Eye Versus No-treatment for the Infra-Orbital Hollows
This is a multicenter, blinded evaluator, randomized, prospective, no treatment control clinical study to identify whether RHA® Redensity Eye (*) is superior to no treatment for the correction of moderate to severe tissue volume…
- Conditions
- Infra-orbital Hollows, Tear-trough Deformity, Wrinkle
- Trial name
- NCT04577898
- Testing
- RHA® Redensity Eye
- Where
- 4 sites in United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Graft Pain, Gingival Recession
MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Postoperative pain as well as bleeding are the most common complications after palatal graft harvesting also postsurgical swelling have been reported , Although different agents were used to protect the denuded areas on the…
- Trial name
- NCT03728244
- Testing
- MEBO ointment, Hyaluronic Acid gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tear Trough Hollowing, Under Eye Bags
Platelet Rich Fibrin for Tear Trough Rejuvenation
The purpose of this study is to investigate the efficacy and longevity of Platelet Rich Fibrin (PRF) in combination with hyaluronic acid filler for cosmetic volume restoration of the tear troughs.
- Trial name
- NCT03313934
- Testing
- Hyaluronic Acid Filler and Platelet Rich Fibrin (PRF), Hyaluronic Acid Filler and Saline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rejuva Medical Aesthetics
Osteoarthritis, Knee
Hyaluronic Acid vs Platelet Rich Plasma: Effects on Clinical Outcomes and Intra-articular Biology for the Treatment of Knee Osteoarthritis
In this, prospective, double-blind study, patients with mild to moderate symptomatic knee osteoarthritis will be randomized to receive either a series of leukocyte poor, platelet-rich plasma or hyaluronic acid injections under…
- Trial name
- HA vs PRP (NCT02588872)
- Testing
- Platelet-rich Plasma (PRP), Hyaluronic Acid
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
TMJ Disc Disorder
Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
- Trial name
- NCT06441279
- Testing
- intra-articular injection with Platelet lysate (PL)., intra-articular injection with Hyaluronic Acid.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University