Clinical trials: Hybrid Training
Stroke, Gait, Hemiplegic
A Comparison Between the Exoskeleton Hybrid Assistive Limb and Conventional Gait Training Early After Stroke
Overall aim is to evaluate HAL for gait training early after stroke and the effect of HAL on short- and long-term functioning, disability and health compared to conventional gait training as part of an inpatient rehabilitation…
- Conditions
- Stroke, Gait, Hemiplegic, Ambulation Difficulty, Hemiparesis
- Trial name
- HAL-RCT (NCT02410915)
- Testing
- Hybrid Assistive Limb (HAL); gait training, Control Group; Conventional gait training
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Danderyd Hospital
Cardiovascular Diseases, Stroke Sequelae
Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility
Stroke is a leading cause of long-term disability and death worldwide, with chronic survivors often experiencing gait disturbances (affecting up to 80%), reduced physical activity, and cardiometabolic comorbidities like obesity…
- Trial name
- NCT07420595
- Testing
- Weeks 1-6: EAGT (exoskeleton/end-effector devices; 30- 50% body-weight support, speed 1.5-2 km/h, ≥800-1200 steps/session). Weeks 7-12: CGT (overground walking, obstacles, stairs, dual-tasks)., Full 12 weeks CGT, progressing complexity and demands.
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Iqra National University
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Type 1 Diabetes
Evaluation of The Postprandial Impact of Automated Priming Bolus for Full Closed Loop Insulin Delivery
The purpose of this study is to understand the impact of the automated priming boluses on the safety and feasibility of a new fully automated AP controller.
- Trial name
- Rocket-BPS (NCT05528770)
- Testing
- FCL+BPS, FCL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Marc Breton
Stroke, Rehabilitation
The Feasibility and Therapeutic Effect of Hybrid End-effector Robot-assisted Gait Training With an Active-assisted Module in Chronic Stroke Survivors
Walking rehabilitation after stroke is most effective during the first three months of recovery, but even in the chronic phase-beyond six months post-stroke-a significant number of patients still show potential for gait…
- Conditions
- Stroke, Rehabilitation, Robotic Rehabilitation
- Trial name
- NCT07034521
- Testing
- HIWIN MRG-P110
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease (PD)
Enhanced Tai Chi for Parkinson's Disease (Enhanced Tai Chi PD)
This pilot study evaluates whether a structured, Parkinson's disease-specific Tai Chi programme ("Enhanced Tai Chi") can improve motor and non-motor symptoms in people with Parkinson's disease (PD).
- Trial name
- ETC-PD (NCT07297368)
- Testing
- Enhanced Tai Chi (Enhanced-Tai-Chi-PD), Usual Treatment (Standard Clinical Care)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Burnout Among First Year Residents
Online MedEd Intern Bootcamp: Hybrid (Online+Live) Training for First Year Residents
This study is testing a web-based "Intern Boot Camp" from Online MedEd to see if it can make the first year of residency less stressful for new internal-medicine doctors at Harlem Hospital.
- Trial name
- 2024-OME-RCT (NCT06970340)
- Testing
- Online MedEd Intern Bootcamp
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Autism Spectrum Disorder
Hybrid Computerized EF Training Using Virtual Human Stimuli for Autism
The goal of this pilot clinical trial is to learn the preliminary feasibility and efficacy of a home-based hybrid computerized executive function (EF) training program using social stimuli for autistic individuals.
- Trial name
- NCT07308210
- Testing
- Hybrid computerized executive function training
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Education University of Hong Kong
Stress Disorders, Post-Traumatic, Psychotherapy
SMART Therapist Training: A Hybrid Factorial-SMART Design
Cognitive Processing Therapy (CPT) is highly effective in randomized controlled trials, but its effectiveness drops substantially in standard clinical practice, largely due to therapist "drift" from fidelity to the protocol.
- Trial name
- SMART (NCT07010770)
- Testing
- Web-Based Training (WBT), Work Sample Review (WR), Step down to fidelity self-monitoring
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Wounds, Wounds and Injuries
Hybrid Simulation Training on Nursing Students
To investigate the effects of hybrid simulation training on nursing students' wound care knowledge, skills and compassion competence. Design: This study was a randomised controlled experimental design.
- Conditions
- Wounds, Wounds and Injuries, Wound Heal
- Trial name
- NCT06761690
- Testing
- hybrid simulated wound training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- EDA UNAL
Lethal Means Safety, Brief Intervention
Testing Family Firearm Secure Storage Training (FFAST) to Prevent Suicide
Firearms are the lethal means used in over 70% of Veteran suicides with rates of Veteran deaths via self-induced firearm injury rising dramatically (by 64.8%) from 2001 to 2022.
- Conditions
- Lethal Means Safety, Brief Intervention, Concern Significant Others
- Trial name
- FFAST RCT (NCT07692854)
- Testing
- The Family Firearms Secure storage Training (FFAST) Intervention, Health and Stress Counseling
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cerebral Palsy
Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Evidence from literature support the use of Botulinum toxin A (BoNT-A) for upper limb spasticity management in children with cerebral palsy (CP).
- Trial name
- NCT03302871
- Testing
- Botulinum toxin type A, transcranial direct current stimulation, hybrid training model of CIMT and BIT
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Advanced Life Support, Simulation Training
Effect of Hybrid Simulation Method on Advanced Life Support Application of Nursing Students
The use of simulation in nursing education is an effective way to provide professional skills and enrich learning experiences while protecting patient safety.
- Conditions
- Advanced Life Support, Simulation Training, Nursing Education, Nursing Students
- Trial name
- NCT06425965
- Testing
- Advanced life support training with high fidelity simulator, Advanced life support training with web-based simulation, Advanced life support training with hybrid simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Leukemia, Acute Leukemia
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children and, along with lymphoblastic lymphoma, represents the most common group of childhood lymphoid malignancies.
- Conditions
- Leukemia, Acute Leukemia, Acute Lymphoid Leukemia, Lymphoblastic Lymphoma
- Trial name
- STEP-ALL (NCT07634653)
- Testing
- Exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Non-Small Cell Lung Cancer
Hybrid Prehabilitation Before Thoracic Surgery
Background and study aims: Lung cancer is a leading cause of cancer-related deaths worldwide. Patients with non-small cell lung cancer often undergo lung surgery to remove the tumor.
- Trial name
- HYBREATH (NCT06866717)
- Testing
- Hybrid prehabilitation, Center-based prehabilitation
- Where
- France
- Volunteers
- 38 people
- Sponsor
- ADIR Association
Women's Health, Hybrid Training
Hybrid Training and Middle Age
Modern living and physical inactivity results in many ailments, including obesity, non-alcoholic fatty liver disease (NAFLD), and inflammatory issues.
- Conditions
- Women's Health, Hybrid Training, Middle Aged, Non-alcoholic Fatty Liver Disease
- Trial name
- NCT05231564
- Testing
- hybrid training
- Where
- Iran
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Implementation Research
Implementation of Naturalistic Developmental Behavioral Intervention (NDBI) Through Coaching Caregivers of Young Autistic Children
Naturalistic developmental behavioral interventions (NDBIs) are a newer class of evidence-based interventions for young autistic children to promote their positive developmental or behavioral outcomes.
- Trial name
- NCT06923553
- Testing
- NDBIs
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas at Austin
Physical Fitness, Athletic Performance
Physiological and Performance Characteristics of HYROX Athletes
HYROX© is a fast-growing fitness competition that combines long-distance running with functional exercises such as sled pushes, rowing, and weightlifting movements.
- Conditions
- Physical Fitness, Athletic Performance, Body Composition
- Trial name
- NCT07873840
- Testing
- No Intervention: Observational Cohort
- Where
- Portugal
- Volunteers
- 66 people
- Sponsor
- Atlantica - Instituto Universitario
Stroke
Reaching Training Based on Robotic Hybrid Assistance for Stroke Patients ( RETRAINER-S2 )
Stroke is the third most common cause of death and the main cause of acquired adult disability in high-income countries. The most common deficit after stroke is motor impairment of the contralateral arm, with more than 80% of…
- Trial name
- RETRAINER-S2 (NCT03199833)
- Testing
- RETRAINER-S2, Conventional therapy
- Where
- 2 sites in Germany, Italy
- Volunteers
- 68 people
- Sponsor
- Dr. Franco Molteni
Constipation, Constipation - Functional
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle…
- Conditions
- Constipation, Constipation - Functional, Dyssynergia
- Trial name
- NCT05823259
- Testing
- Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami