Clinical trials: Hydrocephalus, Communicating
Ehlers Danlos Syndrome, External Hydrocephalus
Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life
It is known that 33-50% of Classic and Hypermobile Ehlers-Danlos Syndrome patients eventually develop dysautonomia, otherwise known as "POTS" (Postural Orthostatic Tachycardia Syndrome).
- Conditions
- Ehlers Danlos Syndrome, External Hydrocephalus, Dysautonomia, Postural Orthostatic Tachycardia Syndrome
- Trial name
- NCT01367977
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Genetic Disease Investigators
Hydrocephalus, Hydrocephalus, Communicating
Pilot Study to Evaluate the CereVasc® EShunt® System in the Treatment of Communicating Hydrocephalus
The purpose of this study will be to evaluate a novel, minimally invasive method of treating hydrocephalus in adults. The eShunt® System includes a proprietary eShunt® Delivery System and the eShunt® Implant, a permanent implant…
- Trial name
- NCT05501002
- Testing
- eShunt® Implant
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- CereVasc Inc
Hydrocephalus, Communicating
A Prospective Observational Study of Perioperative Lumbar Puncture Pressure and Shunt Valve Pressure Management in Patients with Communicating Hydrocephalus Undergoing Lumboperitoneal Shunt Surgery
Target population: patients 18 years of age or older who require surgical treatment with lumboperitoneal shunt surgery for traffic hydrocephalus Estimated sample size: 30 cases.
- Trial name
- LPP-LPS (NCT06642129)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Intracerebral Hemorrhage, Obstructive Hydrocephalus
A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage
The purpose of this study is to determine if usage of early lumbar drainage leads to less shunt surgery and less catheter associated complications in patients with communicating hydrocephalus after intracerebral hemorrhage with…
- Trial name
- LUCAS-IVH (NCT01041950)
- Testing
- Lumbar drainage
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hydrocephalus
ETV Versus Shunt Surgery in Normal Pressure Hydrocephalus
The purpose of this study is to test and compare the efficacy of Endoscopic Third Ventriculostomy with shunting of Cerebrospinal fluid (CSF)for treatment for patients of Normal pressure Hydrocephalus.
- Trial name
- NCT00946127
- Testing
- Ventriculoperitoneal Shunt Placement, Endoscopic Third Ventriculostomy(ETV)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Communicating Hydrocephalus, Cerebral Intraventricular Hemorrhage
The Safety and Efficacy of Rapamycin on Communicating Hydrocephalus Secondary to Intraventricular Hemorrhage
This prospective, multicenter, open-label clinical trial is designed to evaluate the safety and efficacy of rapamycin in the treatment of communicating hydrocephalus secondary to intraventricular hemorrhage.
- Conditions
- Communicating Hydrocephalus, Cerebral Intraventricular Hemorrhage, Secondary Normal Pressure Hydrocephalus, Post Hemorrhagic Hydrocephalus
- Trial name
- Saturn (NCT06563817)
- Testing
- Rapamycin
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Beijing Tiantan Hospital
Communicating Hydrocephalus
Third Ventriculostomy Versus Shunt for Children With Hydrocephalus
Ventriculoperitoneal shunts are the standard of care for patients with communicating hydrocephalus, but they have a high failure rate - up to 40% fail within 1 year and 50% fail within 2 years.
- Trial name
- NCT01801267
- Testing
- Endoscopic third ventriculostomy (ETV), Ventricular shunt
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Duke University
Normal Pressure Hydrocephalus
Endoscopic Third Ventriculostomy Versus Ventriculo-peritoneal Shunting in Idiopathic Normal Pressure Hydrocephalus
An endoscopic third ventriculostomy is considered to be successful in idiopathic normal pressure hydrocephalus (iNPH) in some literature reports, but there is a lack of high quality data.
- Trial name
- NCT03245138
- Testing
- Endoscopic Third Ventriculostomy, Ventriculo-Peritoneal Shunting
- Where
- 3 sites in Germany
- Volunteers
- 100 people
- Sponsor
- University Medicine Greifswald
Hydrocephalus, Communicating, Hydrocephalus
The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt)
The eShunt™ System is a minimally invasive method of treating communicating hydrocephalus. The eShunt System includes a proprietary eShunt Delivery System and the eShunt Implant, a permanent implant deployed in a minimally…
- Trial name
- ETCHES I (NCT04758611)
- Testing
- eShunt™ Implant
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- CereVasc Inc