Clinical trials: Hydrocephaly
Intraventricular Hemorrhage, Spina Bifida
Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH)
A collection of biological samples (cerebrospinal fluid [CSF] and blood) from patients under 6 years of age who are diagnosed with intraventricular hemorrhage or spina bifida.
- Trial name
- NCT02386228
- Testing
- collection of CSF and blood
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Hydrocephalus, Cerebral Ventricle
Impact of Cerebral Ventricular Dilatations and Cerebrospinal Fluid Pulsations on Periventricular White Matter in Hydrocephalic Patients
Hydrocephalus is characterized by excessive accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. One of the forms of hydrocephalus is called "normal pressure", although one of the main signs is precisely an…
- Conditions
- Hydrocephalus, Cerebral Ventricle, Cerebrospinal Fluid, White Matter Fiber
- Trial name
- HYDRODIFF (NCT05825521)
- Testing
- MRI
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Walking, Cognitive Function
Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia
The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia…
- Trial name
- NCT00494689
- Where
- 2 sites in Singapore
- Volunteers
- 30 people
- Sponsor
- Devathasan Neurology Practice Pte Ltd
Subarachnoid Hemorrhage, Hydrocephalus
Strategies for Weaning From External Ventricular Drainage
External ventricular drainage is frequently used in neurocritical care, particularly in patients admitted for non-traumatic subarachnoid hemorrhage who develop hydrocephalus and/or intracranial hypertension.
- Conditions
- Subarachnoid Hemorrhage, Hydrocephalus, Intracranial Hypertension, External Ventricular Drainage
- Trial name
- SEVDVE2 (NCT07630051)
- Testing
- Direct clamping of external ventricular drain, Progressive (gradual) weaning of external ventricular drain
- Where
- 5 sites in France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Angers
Multiple Sclerosis
Head Circumference Growth in Children Who Develop Multiple Sclerosis Later in Life
Multiple sclerosis patients commonly develop generalized ventricular dilation with or without cerebral atrophy over time. Case studies in the literature have noted some multiple sclerosis patients develop the typical "normal…
- Trial name
- NCT01377805
- Where
- United States
- Sponsor
- Genetic Disease Investigators
Developing the ABEP-H, Determining the Effect of ABEP-H
The Effect of an Avatar-Based Education Program on Shunt Complications and Parents' Knowledge and Care Skills
Hydrocephalus is a common childhood neurosurgical disease. Ventriculoperitoneal (VP) shunt is usually used in the treatment of hydrocephalus. However, VP shunt may have some complications.
- Trial name
- NCT05370131
- Testing
- Avatar-Based Education Program in Hydrocephalus (ABEP-H)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hydrocephalus, Alzheimer Disease
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.
- Trial name
- NCT04099823
- Testing
- MRI screening form, Urine pregnancy test, MR brain
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hydrocephalus in Infants
Non-Invasive Pressure Monitor for Neonates & Infants at Risk of Developing Hydrocephalus
The goal of this clinical trial is to test a modified smart soft contact lens in neonates and infants at risk of developing hydrocephalus.
- Trial name
- NCT06310213
- Testing
- Non-Invasive Pressure Monitor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Hydrocephalus, Intracranial Hypertension
Brain Ultrasound in the Weaning of External Ventricular Leads
External Ventricular Deviation (EDV) is a medical device that provides transient and controlled external drainage of cerebrospinal fluid (CSF). This device can also monitor intracranial pressure (ICP).
- Trial name
- ECHO-SD (NCT03531723)
- Testing
- Measuring the size of the 3rd ventricle by ultrasound
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Chronic Hydrocephalus
NIMIP: Non Invasive Measurement of the Intracranial Pressure
The intracranial pressure (ICP), defined by the hydrostatic pressure of the cerebrospinal fluid (CSF), is a key parameter for diagnosing and treating several neurosurgical diseases.
- Trial name
- MINIPIC (NCT01685450)
- Testing
- Echodia® hand-held equipment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hydrocephalus
Noninvasive Intracranial Pressure and Hydrocephalus Patients
Using a pulse oximeter, we have developed an algorithm that estimates intracranial pressure (ICP) based on patients who have had traumatic brain injuries.
- Trial name
- NCT02404740
- Testing
- Pulse oximetry
- Volunteers
- 163 people
- Sponsor
- University of Colorado, Denver
Hydrocephalus, Hydrocephaly
Hydrocephalus iPad-App Based Intervention Study
This is a pilot study examining the feasibility and efficacy of using Apple iPad applications ("apps") during therapy interventions that target visual motor, visual attention, and visual-spatial reasoning skills in school age…
- Conditions
- Hydrocephalus, Hydrocephaly, Hydrocephalus in Children
- Trial name
- NCT03595033
- Testing
- iPad app-based intervention
- Volunteers
- 14 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Normal Pressure Hydrocephalus
Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus
The research project is designed to determine which combination of tests will enable physicians to predict whether a patient with symptoms of normal pressure hydrocephalus (NPH) will improve with a shunt.
- Trial name
- NPH (NCT00613886)
- Testing
- Programmable Shunt Insertion (Codman, Medtronic), Assessments in physical therapy, occupational therapy, and speech therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Irvine
Hydrocephalus
A Study Comparing Two Treatments for Infants With Hydrocephalus
The purpose of this study is to study whether infants with triventricular hydrocephalus (TVH) have a better long-term outcome at 5 years when they are treated with a new procedure, endoscopic third ventriculostomy (ETV), than…
- Trial name
- NCT00652470
- Testing
- Endoscopic Third Ventriculostomy, CSF Shunt Insertion
- Where
- 22 sites in United States, Argentina and 14 more
- Volunteers
- 182 people
- Sponsor
- The Hospital for Sick Children
Investigate the Effect of External Lumbar Cistern Drainage in Preventing Postoperative Hydrocephalus in Patients Who Have Undergone Meningioma Surgery
Impact of External Drainage of the Lumbar Cistern in Patients With Hydrocephalus Following Meningioma Surgery and Its Influence on Patient Satisfaction
This study aims to investigate the effect of external lumbar cistern drainage in preventing postoperative hydrocephalus in patients who have undergone meningioma surgery and its impact on patient satisfaction.
- Trial name
- NCT06383169
- Where
- China
- Volunteers
- 86 people
- Sponsor
- First Hospital of Zhangjiakou City
Hydrocephalus
Role of Endoscopic Third Ventriculostomy Imanagement of Hydrocephalus in Pediatric Age Group; Clinical and Surgical Outcome
Endoscopic third ventriculostomy in cases of hydrocephalus provide less invasive and safe technique than ventriculoperitoneal Shunt also decrease complications of ventriculoperitoneal Shunt
- Trial name
- NCT07694518
- Testing
- Fenestration of the floor of the third ventricle, Endoscopic third ventriculostomy of the brain third ventricle, Endoscopic third ventriculostomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Hydrocephalus, Normal Pressure
MRI-Volumetry in the Evaluation of Shunt Treatment for Hydrocephalus
This randomized, double-blinded, cross-over study aim to evaluate the effects of shunt treatment in idiopathic normal pressure hydrocephalus (iNPH) by measuring cerebral ventricular volume and clinical symptoms at different shunt…
- Trial name
- NCT04599153
- Testing
- Ventriculoperitoneal shunt opening pressure setting
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Uppsala University
Hydrocephaly
Quantitative Characterization of Safe Irrigation for Ventricular Shunt Catheters
The objective of this pilot study is to perform a set of pressure and flow rate measurements in order to quantitatively characterize safe irrigation or "flushing" of a ventricular shunt catheter, a routine maneuver performed by a…
- Trial name
- NCT02651337
- Testing
- Cerebrospinal Fluid (CSF) Drainage
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Alcyone Therapeutics, Inc
Hydrocephalus
Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device
This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a study subject during activities of daily living and sleep
- Trial name
- NCT07050628
- Testing
- wireless thermal anisotropy measurement device
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Rhaeos, Inc.