Clinical trials: Hydroxyapatite
Osteoarthritis
The Effect of Implant Coating (BoneMaster) on Migration and Clinical Outcome in Hip Arthroplasty With the Exceed Cup
This study focuses on the effect of the hydroxyapatite coating with BoneMaster on the fixation of the hip prosthesis in primary hip alloplasty.
- Trial name
- NCT02311179
- Testing
- Prosthesis, BoneMaster-Exceed cup (Biomet), Prosthesis Exceed cup without HA (Biomet)
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Aarhus
Alveolar Cleft
Assessment of Nanocrystalline Hydroxyapatite Versus Autogenous Bone Grafts : A Comparative Clinical Study in Alveolar Cleft Grafting
This work aims to evaluate Nanocrystalline Hydroxyapatite versus Autogenous bone grafts in alveolar cleft grafting
- Trial name
- NCT04693559
- Testing
- secondary alveolar bone graft, harvesting of the autogenous bone graft, Nanocrystalline Hydroxyapatite
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Tooth Hypersensitivity
Hypersensitivity and Color Changes of Bleached Teeth Using Different Remineralizing Agents
The aim of this in vivo study is to evaluate the post-bleaching enamel hypersensitivity and the possible color changes following the application of arginine and nano-hydroxyapatite remineralizing solutions after enamel bleaching…
- Trial name
- NCT04875000
- Testing
- Remineralizing agent I application, Remineralizing agent II application, Remineralizing agent III application
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Femoral Neck Fractures
Retrieval Study and Histological Examination Of A Hip Femoral Components With Hydroxyapatite Coatings
Retrieval study and histological examination of BiMetric Femoral Components with hydroxyapatite coatings.
- Trial name
- NCT00757653
- Testing
- Hip stem with plasma sprayed porous Ti 6Al4V alloy + plasma sprayed HA, Hip stem with plasma spayed porous Titanium 6Al4V alloy + Bonemaster HA, Hip stem with Interloc Titanium surface + Bonemaster H.A
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Zimmer Biomet
Lumbar Fracture, Thoracic Fracture
Percutaneous Injection Plus Short Segment Pedicle Screw Fixation for Traumatic A2 and A3 AO-type Fractures in Adults
The aim of this study was to examine the short- to medium-term efficacy of percutaneous vertebral body reconstruction by vertebral body augmentation with Sr-HA paste plus short-segment pedicle screw fixation in fresh fractures…
- Trial name
- NEOGEL (NCT03431519)
- Testing
- VP
- Volunteers
- 38 people
- Sponsor
- University Hospital of Patras
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Regeneration of Alveolar Sockets With rhBMP-2-loaded Bovine Bone Mineral
Aim of the present investigation will be to evaluate the efficacy and safety of a granulate of rhBMP-2- loaded bovine bone mineral (rhBMP-2-BBM) as alveolar bone regeneration procedure following tooth extraction.
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Edentulous Alveolar Ridge
- Trial name
- PROTEOGRAFT (NCT05717478)
- Testing
- rhBMP-2-BBM, Bio-Oss+Bio-Gide
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Primary Disease
Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling
The first year purpose: The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.
- Trial name
- NCT01323894
- Where
- Taiwan
- Volunteers
- 3 people
- Sponsor
- China Medical University Hospital
Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur
FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
The goal of this clinical trial is to investigate the new bone formation around a metal device in the femoral head in patients with osteoporotic hip fractures undergoing surgical treatment with nails.
- Conditions
- Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, Low
- Trial name
- NCT06135298
- Testing
- OSTEOSYNTHESIS, Zoledronic acid, CERAMENT BONE VOID FILLER (BVF)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Aksaray University
Healthy Volunteers, Discoloration of Teeth
Evaluation of Tooth Sensitivity and Whitening Effects of Different Content Teeth Whitening Agents
The goal of this clinical study is to evaluate the success of different whitening agents in whitening teeth in healthy volunteers aged 18-50. Also, patients' tooth sensitivity will be assessed after application.
- Conditions
- Healthy Volunteers, Discoloration of Teeth, Bleaching Sensitivity
- Trial name
- NCT06855940
- Testing
- Bleaching Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Betül Tokat
Osseointegration Failure of Dental Implant
Effectiveness of Hydroxyapatite Reinforced Chitosan Hydrogel in Modulation of Osseointegration
Dental implant treatments have now become indispensable in clinical dental practice. The survival rate exceeds 90%; Modern oral implantology uses different devices, in terms of size, shape, length, thickness and composition, from…
- Trial name
- NCT06758440
- Testing
- chitosan
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Skull Defects, Cranioplasty
Comparison of Individual Computer Aided Design/Manufactured (CAD/CAM) - Based Implants Consisting on Hydroxylapatite and Titanium to be Used in Cranioplasty
The purpose of this study is to compare the results of cranioplasty with CAD/CAM (computer aided design/manufactured) based Hydroxylapatite and Titanium implants in respect to infections, re-operations, antibiotic treatment or…
- Trial name
- NCT00923793
- Testing
- Titanium implant (CranioConstruct™), Hydroxylapatite (CustomBone)
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University of Leipzig
Tooth Extraction
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink".
- Trial name
- NCT07154693
- Testing
- Combination 70% FDBA and 30% DFDBA, OsteoGen Plug
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Bone Substitutes, Calcium Phosphates
Biphasic Calcium Phosphate vs. Hydroxyapatite in Sinus Floor Elevation
Twenty patients scheduled for lateral-window sinus floor Elevation (SFE) are randomized into two groups: use of SYMBIOS® Biphasic Bone Graft Material (Group 1) or of Algipore® Bone Substitution Material (Group 2).
- Conditions
- Bone Substitutes, Calcium Phosphates, Hydroxyapatite, Rhodophyta
- Trial name
- NCT04331314
- Testing
- Use of Symbios Bone Graft Material, Algipore Bone Substitution Material
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Cellulite
Effects of Calcium Hydroxylapatite on Cellulite Dimples in the Buttocks
The goal of this clinical trial is to test the efficacy of Calcium Hydroxylapatite (CaHA) in treating cellulite dimples in the buttocks.
- Trial name
- NCT05885035
- Testing
- Calcium Hydroxyapatite
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kalpna Kay Durairaj, MD, FACS
Dental Implant, Hydroxyapatite
Clinical Study of Implants With Modified Surface Treatment
The observed medical device in this study were SGS P7D Dental implant. The device replaces the lost tooth root, and provides support for the dental bridges and crowns, or overdenture replacements.
- Trial name
- NCT06034171
- Testing
- dental implant
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- SmileDent Kft.
Caries
The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.
The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes.
- Trial name
- NCT04906291
- Testing
- Toothpaste use
- Where
- Italy
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Chronic Periodontitis
Plaque Formation Rate and Toothpaste
This 12-week prospective, randomized, double-blind, two-center trial evaluated the impact of a microcrystalline zinc-hydroxyapatite (mHA) dentifrice on plaque formation rate (PFR) in periodontitis patients.
- Trial name
- PFR (NCT02697539)
- Testing
- AmF/SnF2, mHA
- Volunteers
- 74 people
- Sponsor
- University Hospital Muenster
Periodontal Disease
EMD and/or Bone Substitute for the Treatment of Class II Furcations
To clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft make of beta tricalcium phosphate/hydroxyapatite (βTCP/HA).
- Trial name
- NCT02474498
- Testing
- EMD, βTCP/HA, Flap access surgery
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Campinas, Brazil
Tibia Fracture Non Union Bone
Study to Analyze the Effects of EBI OsteoGen™ on the Surgical Reconstruction of Tibia Non-unions
The purpose of this clinical outcomes collection study is to analyze the effect of the EBI OsteoGen™ Direct Current Stimulator upon surgical reconstruction of tibia nonunion (no visible progressive signs of healing) fracture in a…
- Trial name
- NCT00726193
- Testing
- OsteoGen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Zimmer Biomet
Dentin Hypersensitivity
Ca-hydroxyapatite, Fluoroapatite, and Mg-Zn-hydroxyapatite for Dentin Hypersensitivity Management
This will be a double-blind, randomized, three-arm parallel groups study of the effect of toothpastes containing Ca-hydroxyapatite (HAP), Mg-Zn-hydroxyapatite (Zn-Mg-HAP), or fluoroapatite (FAP).
- Trial name
- NCT04896294
- Testing
- Hygienic procedure (toothbrushing using HAP-containing toothpaste), Hygienic procedure (toothbrushing using Zn Mg HAP-containing), Hygienic procedure (toothbrushing using FAP-containing toothpaste)
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University