Clinical trials: Hydroxyapatite
Arthritis of Hip, Hip Dysplasia
Nexus Evaluation Primary Trident II Uncemented Shell
This is a prospective cohort study assessing the survival of a new acetabula component which is based on the original Trident acetabular system (cementless shell) which is used for Total Hip Arthroplasty.
- Conditions
- Arthritis of Hip, Hip Dysplasia, Hip Arthropathy, Hip Osteoarthritis
- Trial name
- NEPTUNE (NCT05366712)
- Testing
- Stryker Trident® II HA coated cementless acetabula component
- Where
- United Kingdom
- Volunteers
- 125 people
- Sponsor
- NHS Lothian
Coronary Artery Disease
Hydroxyapatite Active Pro Healing Clinical Trial Program
The purpose of this first feasibility study is to evaluate the performance of Vesta™ \& VestaCOR™ (Hydroxy-Apetite coated GenX) stent in de novo native coronary artery lesions.
- Trial name
- HApFIM (NCT00474084)
- Testing
- Intravascular Coronary Stent
- Volunteers
- 70 people
- Sponsor
- BioSync Scientific Pvt. Ltd.
Dental Implant, Hydroxyapatite
Clinical Study of Implants With Modified Surface Treatment
The observed medical device in this study were SGS P7D Dental implant. The device replaces the lost tooth root, and provides support for the dental bridges and crowns, or overdenture replacements.
- Trial name
- NCT06034171
- Testing
- dental implant
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- SmileDent Kft.
Tooth Extraction
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink".
- Trial name
- NCT07154693
- Testing
- Combination 70% FDBA and 30% DFDBA, OsteoGen Plug
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Intrabony Periodontal Defect
Efficacy of Titanium Granules in the Treatment of Periodontal Intrabony Defects
The ideal goal of the periodontal treatment is not only to prevent the progression of the disease, but also the regeneration and reconstruction of lost tissues.
- Trial name
- NCT04932161
- Testing
- Titanium Granules, Hydroxyapatite
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Caries, Dental
Remineralization Effects of Hydroxyapatite Toothpaste
The objective of this in situ clinical study is to determine whether a toothpaste containing hydroxyapatite microclusters is as effective as a fluoridated kid's toothpaste in promoting remineralization of early caries lesions and…
- Trial name
- NCT03681340
- Testing
- Hydroxyapatite toothpaste, Fluoridated toothpaste
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Open Fracture of Foot
In Vivo Clinical Trial of Porous Starch - Hydroxyapatite Composite Biomaterials for Bone Regeneration
Biodegradable scaffold is an accepted and commercialized medical alternative choice for bone regeneration. In this project we will used our new invention, porous starch- hydroxyapatite composite, for in vivo clinical trial.
- Trial name
- NCT02910232
- Testing
- bone void filler
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Dental Restoration Failure
Clinical Evaluation of Nano Hydroxyapatite Reinforced Glass Ionomer in Treatment of Root Caries in Geriatric Patients
In geriatric patients, will the clinical performance of nano hydroxyapatite reinforced glass ionomer be better than conventional glass ionomer cement in treatment of root caries lesions over one year follow up?
- Trial name
- NCT04701320
- Testing
- Conventional glass ionomer, Nano hydroxyapatite reinforced glass ionomer
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Preservation
Alveolar Ridge Preservation Procedures
Tooth loss is accompanied by different patterns of bone loss. Up to 50% loss of alveolar crestal bone width will likely occur 1 year after tooth loss, especially in the anterior maxilla.
- Trial name
- NCT05419778
- Testing
- Osteogen plug®, MInerOss®
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Periodontal Diseases, Hypersensitivity Dentin
Clinical Efficacy of Vector Paro With Hydroxyapatite in the Supportive Therapy of Periodontitis
Enamel is the most calcified tissue in the body and is composed of 92-96% by organic substances in particular hydroxyapatite. Hydroxyapatite nanoparticles are similar to the morphology and structure of tooth enamel apatite…
- Conditions
- Periodontal Diseases, Hypersensitivity Dentin, Hydroxyapatite
- Trial name
- PAROXY (NCT07482280)
- Testing
- hydroxyapatite debridment, ultrasonic debridment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Subcision, Calcium Hydroxylapatite
Subcision Followed by Diluted Calcium Hydroxylapatite Injection Versus Subcision Followed by Painting CROSS TCA Technique for the Treatment of Atrophic Acne Scars
This study aimed to compare the safety and efficacy of subcision followed by diluted calcium hydroxyapatite injection versus subcision followed by the painting original chemical reconstruction of skin scars (CROSS) technique…
- Conditions
- Subcision, Calcium Hydroxylapatite, Trichloroacetic Acid, Atrophic Acne Scar
- Trial name
- NCT07028567
- Testing
- Calcium hydroxylapatite filler, Painting chemical reconstruction of skin scars trichloroacetic acid technique
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University
Missing Tooth
"Prospective Evaluation of Immediate & Early Loading of Zimmer Hydroxyapatite Coated Dental Implants"
The purpose of this study is to compare the success rates of two surgical protocols. One protocol will have the implants placed at the time of tooth extraction and placed into function.
- Trial name
- NCT02397044
- Testing
- Implant surgery
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Lumbar Fracture, Thoracic Fracture
Percutaneous Injection Plus Short Segment Pedicle Screw Fixation for Traumatic A2 and A3 AO-type Fractures in Adults
The aim of this study was to examine the short- to medium-term efficacy of percutaneous vertebral body reconstruction by vertebral body augmentation with Sr-HA paste plus short-segment pedicle screw fixation in fresh fractures…
- Trial name
- NEOGEL (NCT03431519)
- Testing
- VP
- Volunteers
- 38 people
- Sponsor
- University Hospital of Patras
Chronic Periodontitis
Evaluation of Nano-crystalline Hydroxyapatite Silica Gel in Management of Periodontal Intrabony Defects
A clinical and radiographic evaluation of Nano-crystalline hydroxyapatite silica gel in comparison with open flap debridement for management of periodontal intrabony defects.
- Trial name
- NCT02507596
- Testing
- Nano-crystalline hydroxyapatite silica gel, open flap debridement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cellulite
Effects of Calcium Hydroxylapatite on Cellulite Dimples in the Buttocks
The goal of this clinical trial is to test the efficacy of Calcium Hydroxylapatite (CaHA) in treating cellulite dimples in the buttocks.
- Trial name
- NCT05885035
- Testing
- Calcium Hydroxyapatite
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kalpna Kay Durairaj, MD, FACS
Bone Augmentation
Evaluation of the Safety and Performance of the Neobone®: A Prospective Observational Study in Dental Area
This study aims to collect real-world clinical data to gather information on the performance and safety of the Neobone® when used according to its intended purpose and current clinical applications.
- Trial name
- NeoDent01 (NCT07179497)
- Where
- Portugal
- Volunteers
- 66 people
- Sponsor
- Bioceramed
Retention Rate of Flowable Composite in Demenerlized Pits and Fissure
Retention Rate of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional
Pits and fissures have been considered as the single most important feature leading to the development of occlusal caries; About 90 % of carious lesions are found in the pits and fissures of permanent posterior teeth .Several…
- Trial name
- NCT03264105
- Testing
- Hydroxyapatite Nanofiber reinforced flowable composite, conventional resin-based flowable composite
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentine Hypersensitivity
Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes
Dentin hypersensitivity is a common problem in society. Untreated hypersensitivity affects the patient's quality of life, complicates plaque control and increases the risk of caries and periodontal disease.
- Trial name
- NCT06197555
- Testing
- Sodium Monofluorophosphate, Stannous Fluoride, Nano-Hydroxyapatite
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Dental Caries, Hydroxyapatite
Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults
Target question is as the following one: Does the daily use of a fluoride-free, microcrystalline hydroxyap-atite (HAP) - containing test toothpaste have a non-inferior caries preventing effect in the permanent dentition compared…
- Conditions
- Dental Caries, Hydroxyapatite, Tooth Decay, Dentin, Carious
- Trial name
- CA1 (NCT04756557)
- Testing
- Experimental., Active comparator
- Where
- Poland
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences