Clinical trials: Hydroxychloroquine Retinopathy
Toxic Maculopathy
Incidence and Risk Factor of Hydroxychloroquine and Chloroquine Retinopathy
The purpose of this study is to evaluate the incidence and risk factor of toxic maculopathy who treated with hydroxychloroquine or chloroquine due to their autoimmune disease such as rheumatoid arthritis or systemic lupus…
- Trial name
- NCT02550964
- Testing
- Composite Examination
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Asan Medical Center
Hydroxychloroquine Retinopathy
Novel ERG for Detection of Hydroxychloroquine Retinopathy
The purpose of the study is to investigate novel electroretinography (ERG) devices in the detection of hydroxychloroquine retinopathy.
- Trial name
- NCT06035887
- Testing
- Hand-Held Full-Field Skin-Electrode Electroretinography (Device to be evaluated), Trolley-Mounted Multifocal Skin-Electrode Electroretinography (Device to be evaluated), Spectral-Domain Optical Coherence Tomography (Standard of Care test)
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- King's College Hospital NHS Trust
Retinitis Pigmentosa
Oral Hydroxychloroquine (HCQ) for Retinitis Pigmentosa Caused by P23H- Rhodopsin (RHO)
This research study is being done to learn what effect 12 months of treatment with oral hydroxychloroquine (HCQ) will have on the retina in people with retinitis pigmentosa (RP).
- Trial name
- NCT04120883
- Testing
- Hydroxychloroquine lower dose, Hydroxychloroquine higher dose
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Michigan
Retinal Degeneration, Age-Related Macular Degeneration
Adaptive Optics Imaging of Outer Retinal Diseases
The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement…
- Conditions
- Retinal Degeneration, Age-Related Macular Degeneration, Retinitis Pigmentosa, Hydroxychloroquine Retinopathy
- Trial name
- NCT05355415
- Testing
- Adaptive optics imaging
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Food and Drug Administration (FDA)
Age Related Macular Degeneration
Plaqenil Role in Prevention of Age Related Macular Degeneration
The investigators think that there is a connection between the use of plaquenil and the prevention of Age related macular degeneration (AMD).
- Trial name
- NCT01541449
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Proliferative Nephritis, Chloroquine Retinopathy
Proliferative Lupus Nephritis Treatment With Chloroquine and Hydroxychloroquine
Evaluation the efficacy of chloroquine and hydroxychloroquine in the treatment of proliferative lupus nephritis class III and IV in children and adolescents and evaluate the side effects of both drugs .
- Trial name
- NCT03687905
- Testing
- Chloroquine, Hydroxychloroquine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Hydroxychloroquine Retinopathy
Optical Coherence Tomography Angiography Evaluation Of Patients Taking Hydroxychloroquine
This study aims to evaluate retinal and choroidal microvascular changes using optical coherence tomography angiography (OCTA) in patients receiving hydroxychloroquine therapy.
- Trial name
- NCT07409740
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hydroxychloroquine Toxic Retinopathy
Hydroxychloroquine Dosing and Toxicity in Ophthalmology Clinics
This study assesses the ocular toxicity in patients on high dose hydroxychloroquine (HCQ) as per the latest guidelines of the American Academy of Ophthalmology (AAO).
- Trial name
- NCT04010110
- Testing
- visual field testing (10-2), spectral domain ocular coherence tomography and Fundus auto-fluorescence
- Where
- Saudi Arabia
- Volunteers
- 63 people
- Sponsor
- The Eye Center and The Eye Foundation for Research in Ophthalmology
Genotype, Retinal Disease
Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene
Background: Plaquenil (hydroxychloroquine) is an anti-inflammatory drug that is used to treat some autoimmune diseases such as lupus and rheumatoid arthritis.
- Trial name
- NCT01145196
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- National Eye Institute (NEI)