Clinical trials: Hydroxyethyl Starch
Breast Cancer, Sentinel Lymph Node
A Study for Optimization of 6% Hydroxyethyl Starch Based Indocyanine Green Near-infrared Fluorescence Navigated Sentinel Lymph Node Biopsy for Breast Cancer Patients
A study for dosage-image optimization of 6% hydroxyethyl starch diluted indocyanine green for near-infrared fluorescence navigated sentinel lymph node mapping for breast cancer patient.
- Trial name
- NCT05365204
- Testing
- Near infrared fluorescence navigated sentinel lymph node mapping
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
A Comparison Between 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 in Priming Solution for Cardiopulmonary Bypass and Post-bypass Maintenance Fluid in High-risk Patients
It is advantageous to use 5% human albumin (HA) in patients undergoing cardiopulmonary bypass (CPB), because preexposure of the synthetic surfaces of the CPB circuit to albumin decreases coagulopathy, platelet aggregation, immune…
- Trial name
- NCT01644084
- Testing
- Hydroxyethyl starch 130/0.4
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Total Fluid Volume Increased
Evaluate the Nephrotoxicity by 6% Hydroxyethyl Starch 130/0.4 in Old Patients During Orthopaedic Surgery
Hydroxyethyl starch (HES) is commonly used as plasma expander during surgery but may be nephrotoxic as seen in studies in patients with sepsis.
- Trial name
- NCT02361736
- Testing
- Hydroxyethyl Starch, Lactate Ringers
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yuanyuan Zhang
Patients Undergoing Liver Transplantation
Impact of %6 HES 130/0.4 and %4 Gelofusine Infusion on Kidney Function in the Living-donor Liver Transplantation
Although the negative impacts of colloid solutions with high molecular weight on renal functions, combination of lower molecular weight colloid varieties with crystalloid solutions and its use during intraoperative period have…
- Trial name
- NCT02079350
- Testing
- %6 HES and %4 Gelofusine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Anesthesia Morbidity
Comparing Human Albumin Versus Hydroxyethylstarch in Renal Transplant Recipients
In this study we try to review the possible effects when using modern hydroxyethylstarch solutions 6 % versus albumin 5% during living donor renal transplantation.
- Trial name
- NCT03306914
- Testing
- Albumin resuscitation, Hydroxyethylstarch resuscitation, Albumin 5%
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Trauma
Use of Hextend in Trauma
This is a chart review of all trauma patients during the specified time period. The purpose of this study is to examine the effects of resuscitation with hextend after trauma, in the adult population.
- Trial name
- NCT00983281
- Testing
- Hextend
- Where
- United States
- Volunteers
- 1,714 people
- Sponsor
- University of Miami
Acute Normovolemic Hemodilution, Off-Pump Coronary Artery Bypass Surgery
Acute Normovolemic Hemodilution in Off-pump CABG
To study the effects of Acute normovolemic hemodilution on central and peripheral perfusion in patients Undergoing off-pump coronary artery bypass grafting surgery
- Trial name
- NCT04042883
- Testing
- Acute normovolemic hemodilution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Subarachnoid Hemorrhage
The Mortality and Changes in Quality of Life of Patients Suffering From SAH With Different Hydration Strategies
Purpose: Vasospasm and secondary ischemia following subarachnoidal hemorrhage considerably affect the clinical outcome. The purpose of this study is to determine whether crystalloid (Lactated Ringer's solution) or colloid…
- Trial name
- NCT02064075
- Testing
- Lactated Ringer's solution, Hydroxyethyl starch
- Where
- Hungary
- Volunteers
- 96 people
- Sponsor
- University of Debrecen
Fluid Volume Disorder
Effects of Hypertonic Saline-HES Solution on Extracellular Water in Cardiac Surgery Patients
The aim of the study is to describe the effects of hypertonic saline/hydroxyethylstarch solution in comparison to saline solution for 25 + 25 patients undergoing coronary bypass grafting surgery (CABG) using CPB.
- Trial name
- NCT01348659
- Testing
- 7.2% NaCl/hydroxyethylstarch, NaCl 0.9%
- Where
- Finland
- Volunteers
- 48 people
- Sponsor
- Kati Järvelä
Plasma Volume Substitution (Hypovolemia) Including Massive Hemorrhage
Study to Obtain Volume Effect and Safety Data on 6 % Hydroxyethyl Starch 130/0.4 in Pediatric and Adult Patients Undergoing Major Elective Surgery
The study shall evaluate the volume effect and safety of 6 % hydroxyethyl starch 130/0.4 for restoration and maintenance of hemodynamics during the investigational period in patients undergoing major elective surgery.
- Trial name
- NCT01127477
- Testing
- 1: Hydroxyethyl starch 130/0.4, 6 %
- Where
- 4 sites in Japan
- Volunteers
- 20 people
- Sponsor
- Fresenius Kabi Japan
Urologic Surgical Procedures
Use of Two Modern Hydroxyethyl Starch Solutions in Major Urological Procedures
This study compares the effect of infusion of two types of modern hydroxyethyl starch on the renal function and acid-base in patients undergoing urologic surgery.
- Trial name
- NCT01670604
- Testing
- 6% HES 130/0.4 in NaCl 0.9% (Voluven, Fresenius Kabi, Bad Hom-bourg, Germany), Tetraspan, B. Braun, Melsungen, Germany
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Extracorporeal Circulation, Cardiac Surgery
Priming of Cardiopulmonary Bypass With Hydroxyethyl Starch 130/0.4 or Sodium Chloride 0.9% : Pilot Study in Adult Elective Conventional Cardiac Surgery
Best priming for cardiopulmonary bypass in cardiac surgery is unknown. Efficacy and toxicity of Hydroxyethyl Starch 130/0.4 used in this context are uncertain.
- Trial name
- OPTIMUS-PRIME (NCT02906514)
- Testing
- Non balanced Hydroxyethyl starch 130/0.4 (Voluven®, Fresenius), Sodium Chloride 0.9% (Fresenius)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Kidney Injury
Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients
The purpose of this study is to evaluate the safety of a standard volume replacement called HES 130/0.4 (Voluven) during surgery on recovery.
- Trial name
- SHARP (NCT02192502)
- Testing
- human albumin 5%, HES 130/0.4 (Voluven)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- The Cleveland Clinic
Kidney Function Tests
Effect of Hydroxyethylstarch 6% 130/0.4 Administration on Renal Function After Cardiac Surgery
Recent studies have shown an increased incidence of renal replacement therapy after the use of Hydroxyethylstarchs (HES) in patients admitted in the intensive care unit.
- Trial name
- NCT02306213
- Testing
- Hydroxyethylstarch 6% 130/0.4, standard volume therapy
- Volunteers
- 1,564 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Meningioma of Brain, Meningioma Surgery
Re-bleeding in Giant Meningioma and Intraoperative Hydroxyethyl Starch (HES) Fluid Therapy
Project Summary: Retrospective Cohort Study 1. Core ObjectiveThe primary goal is to determine if the volume of Hydroxyethyl Starch (HES) 130/0.4 (specifically Voluven® or Volulyte®) administered during the removal of giant…
- Trial name
- GM-HES (NCT07476404)
- Testing
- exposure to Hydroxyethyl Starch (HES) Voluven® or Volulyte® 130/0.4
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Chiang Mai University
Lung Injury, Acute (ALI), Respiratory Distress Syndrome, Acute (ARDS)
Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI)
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are similar conditions in which the lungs are critically injured by another inflammatory process in the body.
- Trial name
- CEASE (NCT00796419)
- Testing
- 5% human albumin, 6% hetastarch
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Hypotension
Efficacy of Voluven® for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section
The aim of the study is to evaluate the efficacy of Voluven® in the prevention of maternal hypotension in women undergoing spinal anesthesia for cesarean section
- Trial name
- CAESAR (NCT00694343)
- Testing
- HES 130/0.4 (6%) in sodium chloride (solution for infusion), Ringer's Lactate solution
- Where
- 14 sites in France
- Volunteers
- 167 people
- Sponsor
- Fresenius Kabi
Laminectomy
Hemostatic Effect of Various Colloid Solutions
Background: Individuals with type O blood have reduced factor VIII and von Willebrand factor levels compared to the non-O counterpart.
- Trial name
- NCT00518544
- Testing
- administration of hydroxyehtyl starch
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Cesarean Section, Spinal Anesthesia
Effects of Crystal Solution and Colloid Solution on Mother and Fetus
Comparison of the effects of crystal solution (lactic acid Ringer's solution) and colloid solution (hydroxyethyl starch) on mother and fetus after cesarean section
- Conditions
- Cesarean Section, Spinal Anesthesia, Parturition
- Trial name
- NCT04432675
- Testing
- hydroxyethl starch, Lactated Ringer's solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China International Neuroscience Institution
Coronary Heart Disease
The Effect on Fluid Balance After Cardiac Surgery After Use of Two Different Priming Protocols
"The impact on fluid loading after cardiac surgery by use of two different priming solution" Fluid overloading with oedema formation is a regular finding following on-pump cardiac surgery and may contribute to postoperative organ…
- Trial name
- NCT01511120
- Testing
- Tetraspan, acetated Ringer's solution
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Haukeland University Hospital