Clinical trials: Hydroxyethyl Starch
Adverse Effect
Comparison of Hydroxyethyl Starch and Crystalloid Coload Combined With Norepinephrine Infusion for Hypotension
The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) or crystalloid coload combined with prophylactic norepinephrine infusion dose for postspinal anesthesia hypotension…
- Trial name
- NCT05475990
- Testing
- Hydroxyethyl starch, Crystalloid
- Where
- China
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension
The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Regional anesthesia (spinal, epidural) is considered the method of choice for anesthesia obstetric deliveries because of the ability to use fewer drugs, a more direct experience of childbirth and the capability to provide…
- Trial name
- NCT01835873
- Testing
- Lactated Ringer's, HES 130/0.42
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Intraoperative Complications
Hydroxyethyl Starch (130/0.4) for Intravascular Volume Therapy in Liver Transplantation
There are no standardized plasma volume replacement protocols during liver transplantation surgery. The current study is designed to compare efficacy, safety, and costs of perioperative volume replacement with Voluven…
- Trial name
- NCT00308100
- Testing
- Hydroxyethylstarch 130/0.4, 5% Albumin
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Fresenius Kabi
Coronary Artery Occlusive Disease
The Effect of 6% Hydroxyethyl Starch 130/0.4 on Blood Loss and Coagulation in Patients Medicated With Antiplatelet Agents Prior to Off-Pump Coronary Bypass Graft Surgery
HES 130/0.4 significantly solution will not affect on coagulation and blood loss in patients medicated with antiplatelet agents prior to off-pump coronary bypass surgery (OPCAB).
- Trial name
- NCT01051206
- Testing
- 6% hydroxyethyl Stach 130/0.4
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Yonsei University
Cardiac Surgery
Double Blind Randomized Trial of Saline vs Pentaspan for Resuscitation After Cardiac Surgery
This is a randomized double blind trial of the use of the use of colloids vs crystalloid solutions for resuscitation of patients after cardiac surgery.
- Trial name
- NCT00337805
- Testing
- Pentaspan
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Severe Sepsis, Septic Shock
Scandinavian Starch for Severe Sepsis/Septic Shock Trial
By tradition hydroxyethyl starch (HES) is used to obtain fast circulatory stabilisation in critically ill. High molecular weight HES may, however, cause acute kidney failure in patients with severe sepsis.
- Trial name
- 6S (NCT00962156)
- Testing
- 6% Hydroxyethyl starch 130/0.4, Ringers acetate
- Where
- 26 sites in Denmark, Finland and 2 more
- Volunteers
- 804 people
- Sponsor
- Anders Perner
Cardiac Surgery
Hydroxyethyl Starch Versus Crystalloid and Postoperative Major Adverse Kidney Complications
This trial aims to compare two intraoperative fluids, namely hydroxyethyl starch (HES) and balanced crystalloids in terms of major adverse kidney events after cardiac surgery.
- Trial name
- NCT07410988
- Testing
- Volulyte® (6% HES 130/0.4 in balanced solution), Crystalloid solutions
- Where
- 4 sites in South Korea
- Volunteers
- 1,292 people
- Sponsor
- Seoul National University Hospital
Bloodloss
This Study Will Compare the Effect of Starch Containing to Non-Starch Containing Intravenous Fluid on Blood Loss During Coronary Artery Bypass Graft Surgery
The overall aim of this study is to determine if there is a bleeding risk associated with the use of starch-containing fluids during cardiac surgery.
- Trial name
- NCT00801190
- Testing
- HES (130/0.4), Ringer's Lactate
- Volunteers
- 500 people
- Sponsor
- St. Boniface Hospital
Adverse Effect
Comparison of Different HES Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different 6% hydroxyethyl starch (130/0.4) coload volumes on the 90% effective dose of norepinephrine infusion prophylaxis for hypotension during spinal anesthesia for…
- Trial name
- NCT05712018
- Testing
- Hydroxyethyl starch coload - 0 ml/kg, Hydroxyethyl starch coload - 5 ml/kg, Hydroxyethyl starch coload - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University