Clinical trials: Hygiene
Oral Hygiene
The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
This study will evaluate the effect of experimental sodium fluoride-silica dentifrice formulations, with and without zinc, on remineralization of enamel in situ.
- Trial name
- NCT02195583
- Testing
- Sodium fluoride (1426 ppm), Sodium fluoride (1150 ppm), Sodium fluoride (250 ppm)
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumonia
Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients
Recent studies have found that poor oral hygiene may foster the colonization of the oropharynx by potential respiratory pathogens in mechanically-ventilated (MV), intensive care unit (ICU) patients.
- Trial name
- NCT00123123
- Testing
- chlorhexidine gluconate oral rinse (0.12%)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- State University of New York at Buffalo
Oral Hygiene
To Evaluate the Efficacy and Tolerability of Sodium Bicarbonate Toothpaste
The primary objectives of this study will be to compare the Gingival Bleeding and Gingival Inflammation following twice daily use of a sodium bicarbonate experimental dentifrice compared to a 0% sodium bicarbonate toothpaste…
- Trial name
- NCT02207907
- Testing
- Sodium bicarbonate plus sodium fluoride, Sodium fluoride
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries
Evaluation of Oral Hygiene Products in an In Situ Caries Model
The study will evaluate and compare the potential anti-caries efficacy of a test regimen: placebo (fluoride free) toothpaste (twice daily use) plus fluoride mouthwash (once daily use), in comparison with brushing with a placebo…
- Trial name
- NCT02399163
- Testing
- Fluoride free toothpaste, Fluoride toothpaste, Fluoride mouthwash
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sleep Deprivation
Improving Sleep in Nursing Homes
Older people living in nursing homes do not sleep very well for many reasons. Sleep disorders such as sleep apnea (when someone briefly stops breathing during sleep), and night time urination, along with the problems caused by…
- Trial name
- NCT00576927
- Testing
- Ramelteon
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Emory University
Dentin Sensitivity, Oral Hygiene
A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
The main aim of this study is to investigate the ability of an experimental dentifrice containing 5 percent (%) potassium nitrate (KNO3), 1% alumina and 5% sodium tripolyphosphate (STP), to maintain tooth color and reduce…
- Trial name
- NCT06150573
- Testing
- Test Dentifrice, Reference Dentifrice (Aquafresh Cavity Protection)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- HALEON
Sleep
Adapting Sleep and Yoga Interventions for Maximal Effectiveness in Low Income Populations
The purpose of this study is to evaluate the feasibility of conducting a future randomized control trial that will compare the efficacy of sleep behavioral interventions in a high-risk community including adapted sleep hygiene…
- Trial name
- CALYPSO (NCT03392194)
- Testing
- Sleep hygiene intervention, Yoga intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Brigham and Women's Hospital
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Trial
This Phase II stratified randomized prevention trial will assess the efficacy of a behavioral economic theory-based financial incentive drawing program versus a control regimen to promote early childhood caries (ECC) preventive…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON (NCT03576326)
- Testing
- Drawing Incentive
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Complication of Surgical Procedure
Hand Hygiene and Hospital Acquired Infections
Healthcare-associated infections (HCAIs) and evolving bacterial resistance are major public health concerns that impact all areas of healthcare.
- Trial name
- NCT02252562
- Testing
- Sage Personal Hand Hygiene System
- Where
- 2 sites in United States
- Volunteers
- 3,256 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Gingivitis, Pregnancy
Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)
This study will track changes in oral health in pregnant women. Subjects will be assigned to either regular oral care or advanced oral care and be given oral care products to use until they deliver.
- Trial name
- OHMOM (NCT01549587)
- Testing
- 0.243% sodium fluoride, toothbrush, dental floss
- Where
- 2 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Hand Hygiene Effectiveness
Wet Time for a Foam Hand Sanitizer
Hand sanitizers are a standard of hygiene requirements. They must be effective at reducing germ count on the hands while ideally providing emollients to moisturize the skin after use.
- Trial name
- NCT05740332
- Testing
- Alcohol hand sanitizer foam
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Dental Plaque, Oral Hygiene
Efficacy of Manual Toothbrushes in Removing Dental Plaque
This clinical methodology development study will evaluate the plaque removal efficacy of four marketed manual toothbrushes, with differing bristle types and brush head designs, in healthy dentate participants.
- Trial name
- NCT04025684
- Testing
- Oral B Indicator 123, Dr Best Original, Dr Best Multi Expert
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Excessive Ear Wax
Safety and Effectiveness of an Auricular Spray
The goal of this clinical trial is to test the safety and efficacy of a medical device in subjects with cerumen in excess. The main questions it aims to answer are: Does the medical device induce skin irritation in the ear canal?…
- Trial name
- NCT06085443
- Testing
- Ear Hygiene
- Where
- Poland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- YSLab
Extrinsic Dental Stain, Oral Hygiene
Study to Investigate the Stain Control of Two Stannous Fluoride Dentifrices
The purpose of this study is to evaluate and compare the stain build up of two stannous fluoride (SnF2) / sodium tripolyphosphate (STP) dentifrices of differing abrasivity levels, with a marketed standard fluoride dentifrice and…
- Trial name
- NCT03160703
- Testing
- Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silica, Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), abrasive silica (3.5%), Sodium Monofluorophosphate (1000 ppm fluoride ), RDA~80
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline