Clinical trials: Hyperalimentation and Obesity
Binge Eating, Binge-Eating Disorder
Treating Binge Eating and Obesity Digitally in Women
More than 30% of Black women with obesity binge eat. Binge eating may increase the risk for the development of metabolic syndrome and binge-eating-disorder (BED), which is associated with severe obesity.
- Conditions
- Binge Eating, Binge-Eating Disorder, Weight Gain Prevention, Obesity
- Trial name
- NCT05693896
- Testing
- Centering Appetite
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
Exercise as a Buffer Against Stress-induced Overeating
The purpose of this study is to examine the psychological benefits of chronic exercise as well as the effects of exercise training on eating behaviors and stress-induced overeating in overweight and obese women.
- Trial name
- NCT02936076
- Testing
- Exercise intervention, Delayed exercise intervention
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Early Intervention in Cognitive Aging
Nutritional intervention in overweight middle aged individuals with subjective memory complaints.
- Trial name
- NCT02751866
- Testing
- Berry fruit powder OR nutritional ketosis
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Cincinnati
Obesity, Diet Therapy
Predicting Weight Gain and Weight Loss Associated With Overeating or Fasting
This study will investigate how to better predict why some individuals gain or lose weight more easily than others. It will examine whether the increase in the amount of energy a body burns in 24 hours with overeating or the…
- Conditions
- Obesity, Diet Therapy, Weight Loss, Weight Gain
- Trial name
- NCT00687115
- Testing
- Weight Loss, Overfeeding, Overfeeding Low Pro
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Infant
Determine if Human Infant Weight Gain Can be Modulated to Prevent Obesity
The global obesity epidemic has extended to low and middle income countries (LMICs) in which in a dramatic nutritional transition has shifted from maternal/child undernutrition to overnutrition.
- Trial name
- NCT04526860
- Testing
- Calibration of infant breast milk and formula milk intake
- Where
- Brazil
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Overweight, Obesity and Other Hyperalimentation (E65-E68)
Transcranial Random Noise Stimulation in Food Addiction Treatment
Obesity is worldwide a public health problem. According to World Health Organization (WHO), overweight and obesity are the fifth death risk factor worldwide. At least 2.8 million adults die each year.
- Trial name
- tRNS-FA (NCT02717247)
- Testing
- Active tRNS
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Hôpital le Vinatier
Impulsivity, Compulsive Overeating
tDCS for Impulsivity and Compulsivity in Obesity
Even when they know it can improve health, many individuals with loss of control eating struggle when they are trying to make and sustain new health habits for weight loss and maintenance of weight loss.
- Conditions
- Impulsivity, Compulsive Overeating, Obesity
- Trial name
- NCT04405089
- Testing
- Device: Active Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Overweight, Obesity and Other Hyperalimentation
Nutritional and Physical Activities for Overweight and Obese Older Adults
This cluster randomized trial aims to test nutritional and physical activity interventions in older adults in nursing homes. The overall research question are: o What are the effects of nutritional and physical activity…
- Trial name
- IFEBO (NCT05804019)
- Testing
- Nutritional and physical interventions
- Where
- 6 sites in Denmark
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University College Absalon
Binge-Eating Disorder, Overweight
CHARGE: Controlling Hunger and ReGulating Eating
The objectives of this proposed study are: 1) to evaluate feasibility and acceptability of a novel intervention, Regulation of Cues (ROC), and Cognitive Behavior Therapy (CBT), and 2) to evaluate the efficacy of both treatments…
- Conditions
- Binge-Eating Disorder, Overweight, Obesity
- Trial name
- CHARGE (NCT03678766)
- Testing
- Regulation of Cues (ROC), Cognitive Behavior Therapy (CBT)
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of California, San Diego
Bardet-Biedl Syndrome, POMC Deficiency
Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway
A trial to compare the weekly and daily formulations of setmelanotide in participants with genetic defects in the melanocortin-4 receptor pathway.
- Trial name
- NCT05194124
- Testing
- Setmelanotide 2 mg, Setmelanotide 2.5 mg, Setmelanotide 3 mg
- Where
- 7 sites in United States, Canada and 4 more
- Volunteers
- 19 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity, Eating Disorders
Efficacy and Safety of Rimonabant on Weight Loss and Frequency of Binge Episodes in Obese Patients
The primary objective is to assess the effect of rimonabant compared to placebo on weight loss over a period of 6 months when prescribed with a mild hypocaloric diet in obese patients with binge eating disorder.
- Trial name
- NCT00481975
- Testing
- rimonabant (SR141716)
- Where
- 7 sites in United States, Finland and 5 more
- Volunteers
- 289 people
- Sponsor
- Sanofi
Obesity, Binge Eating
Study of Behavioral Weight Loss Therapy for Obesity and Binge Eating in Monolingual Hispanic Persons
This is a research study designed to examine the effectiveness of an obesity medication (orlistat) given in addition to behavioral weight loss therapy. Participants will be obese monolingual (Spanish-speaking only) men and women.
- Trial name
- NCT00516919
- Testing
- Xenical + behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Binge Eating
Examining Self-tracking Behaviors in a Mobile Intervention for Binge Eating and Weight Management
The purpose of this study is to understand users' experiences and interests completing self-tracking in a mobile intervention for binge eating and weight management.
- Trial name
- NCT04711577
- Testing
- Track clinician-determined symptoms, Track clinician-determined and self-determined symptoms
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Overweight, Obesity
PACIFIC-FIT: Providing Adults Collaborative Interventions for Ideal Changes Focused Intervention and Tracking
The pilot study will be a one group treatment program and will be utilized to refine the M+BWL program.
- Trial name
- NCT03914508
- Testing
- Memory + Behavioral Weight Loss
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of California, San Diego
Stress, Obesity
Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
This is a study of treatment approaches aimed to improve self-control and decrease stress and unhealthy/maladaptive behaviors such as drinking, overeating, and smoking.
- Conditions
- Stress, Obesity, Overeating
- Trial name
- Sync (NCT01721499)
- Testing
- Nutritional Counseling, Mindfulness Intervention
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yale University
Binge Eating Disorder Associated With Obesity, Binge Eating Disorder
A Self-Guided Mobile Intervention for Adults With Binge Eating and Obesity
The proposed study is an open label, non randomized, waitlist controlled single group feasibility study of the feasibility and usability of a digital intervention (called ChangeBite) to be used by individuals with obesity and…
- Trial name
- NCT06817863
- Testing
- Digital
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Drexel University
Obesity and Other Hyperalimentation
Digestion of Foods Consumed in Africa
As populations become urbanized in Africa, the change to a more Westernized diet has been associated with rise in obesity and related metabolic syndrome diseases.
- Trial name
- NCT03007368
- Testing
- Rice, Potato, Pasta
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Overweight, Eating Behavior
Eating Behavior in Adolescents
This study will explore the eating habits of adolescents and determine if eating behavior is linked to genetics. Healthy adolescents between 13 and 17 years of age may be eligible for this study.
- Conditions
- Overweight, Eating Behavior, Binge Eating
- Trial name
- NCT00631644
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Prader-Willi Syndrome
Oxytocin Intranasal Administrations in Children With Prader-Willi Syndrome Aged From 3 to 12 Years
Positive results in preclinical and clinical studies in adults and infants with Prader-Willi syndrome lead investigators to set up a new study in children with Prader-Willi syndrome.
- Trial name
- Oxyjeune (NCT03114371)
- Testing
- Oxytocin
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Pediatric Obesity, Binge Eating
Project TEACH: The Eating, Affect, and Cognitive Health Study
Specific aims are to: 1. Assess variability in performance on state-level measures of working memory (WM) delivered via Ecological Momentary Assessment (EMA).
- Trial name
- NCT04121598
- Testing
- Observational
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh