Clinical trials: Hyperbaric
Radiation Cystitis, Urinary Tract Infection (Diagnosis)
Chronic Radiation Cystitis and Effect of Hyperbaric Oxygen Therapy on Patient Reported Outcomes and Urine Inflammatory Biomarkers
Collection of urine, blood, and tissue samples from patients undergoing hyperbaric oxygen therapy
- Trial name
- NCT07368647
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rachel A. Moses
COVID-19, Desaturation of Blood
Hyperbaric Oxygen Therapy Effect in COVID-19 RCT (HBOTCOVID19)
The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic.So far, no specific treatment has proven efficacy. Recent case series reported the use of Hyperbaric Oxygen Therapy (HBOT) on 5 severe COVID-19 patients…
- Trial name
- HBOTCOVID19 (NCT04358926)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Secondary Hyperalgesia, Inflammation
The Effect of Hyperbaric Oxygen Therapy on Inflammatory Parameters Induced by a Heat Injury Model
Hyperbaric oxygen may reduce neurophatic pain and promote wound healing. Established anti inflammatory effects of HBO may contribute to this effect.
- Trial name
- HBO-SHA (NCT02397343)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pregnancy, Cesarean Section
RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.
This is a prospective, randomized, double blind study of 75 patients (n=25 for each group) in which epinephrine (100mcg or 200mcg) or normal saline vehicle is added to intrathecal hyperbaric bupivacaine (0.75% bupivacaine…
- Trial name
- NCT03335293
- Testing
- 100 mcg Epinephrine, normal saline, 200 mcg Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Osteoradionecrosis
Efficacy of Hyperbaric Oxygen Therapy in the Treatment of Osteoradionecrosis
The purpose of this study is to determine whether hyperbaric oxygen therapy is effective in the treatment of osteoradionecrosis (late complication of radiation therapy) of the jaw.
- Trial name
- NCT00989820
- Testing
- hyperbaric oxygen
- Where
- 8 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Radboud University Medical Center
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Spinal Anesthesia
Effect of Intravenous Dexamethasone on Duration of Hyperbaric Bupivacaine Spinal Anesthesia in Lower Abdominal Surgery
The use of dexamethasone, administered either systemically or perineurally, as an adjunct to peripheral or neuraxial regional blocks, is currently one of the hottest topics in the field of regional anesthesia.
- Trial name
- NCT04778189
- Testing
- i.v dexmethasone
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Hyperbaric Oxygen Therapy, Recovery Time
Hyperbaric Oxygen Therapy in Distal Radius Fractures: Can it Shorten Recovery Time and Increase Fracture Healing?
This project is meant to show wether the HBOT can fasten the recovery process after surgical treatment of distal Radius fractures.
- Conditions
- Hyperbaric Oxygen Therapy, Recovery Time, Contrast Media, Sonography
- Trial name
- HBOTRadius (NCT01365780)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Diabetes Mellitus, Chronic Ulcers of the Lower Limb
Hyperbaric Oxygen Therapy (HBOT) for Chronic Diabetic Lower Limb Ulcers
The purpose of this study is to determine if HBOT plus standard wound care is more effective than standard wound care alone at preventing the need for major amputation (metatarsal and up) in patients with diabetes mellitus (Type…
- Trial name
- HBOT (NCT00621608)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Visceral Pain
Comparison Between Bupivacaine With and Without Fentanyl in Reducing Pain During Cesarean Delivery Under Spinal Anaesthesia
Spinal anaesthesia with hyperbaric bupivacaine is the most commonly used anesthetic technique for cesarean section. Delivery of baby during cesarean section requires traction of peritoneum and handling of intraperitoneal organs…
- Trial name
- NCT05491187
- Testing
- 0.5% bupivacaine heavy, 0.5% bupivacaine heavy with fentanyl
- Where
- Nepal
- Volunteers
- 72 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Breast Cancer, Radiation Dermatitis
Efficacy and Safety of Hyperbaric Oxygen Therapy for Radiation Dermatitis in Patients with Localized Breast Cancer
This study aimed to evaluate reducing the incidence of radiation dermatitis by assigning hyperbaric oxygen therapy to patients with localized breast cancer.
- Trial name
- HBOT (NCT06158347)
- Testing
- hyperbaric oxygen chamber
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Ilsan Cha hospital
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Correlation Between VCL, AC and Spread of Intrathecal Hyperbaric Bupivacaine in the Term Parturient
Currently there is no guideline to decide on the most appropriate dose of spinal anaesthesia. This study is planned to find out factors that influence the effect of spinal anaesthesia in pregnant mother going for Caesarean…
- Trial name
- NCT03606525
- Testing
- subarachnoid block
- Where
- Malaysia
- Volunteers
- 130 people
- Sponsor
- University of Malaya
Diabetic Foot Ulcer Neuropathic
Hyperbaric Oxygen Therapy in Diabetic Foot
This study seeks to assess changes in genes that are related to inflammation and oxidative stress in patients with type 2 Diabetes with diabetic foot treated with hyperbaric chamber
- Trial name
- HBOTDF (NCT06502808)
- Testing
- Hyperbaric oxygen therapy
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- National Polytechnic Institute, Mexico
Hyperbaric Oxygen Therapy, Neuroprotective
Hyperbaric Oxygen Therapy as a Neuroprotective Intervention in Pediatric Acquired Brain Injury With Cognitive Disability
This research aimed to investigate the effectiveness of hyperbaric oxygen therapy as a neuroprotective strategy for improving neurological outcomes in pediatric patients who have sustained acquired brain injury.
- Conditions
- Hyperbaric Oxygen Therapy, Neuroprotective, Pediatric, Acquired Brain Injury
- Trial name
- NCT06954376
- Testing
- Hyperbaric oxygen therapy, Conventional rehabilitation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kafrelsheikh University
Intrathecal Injection, Hyperbaric Prilocaine
Intrathecal Injection of Hyperbaric Prilocaine Versus Hyperbaric Bupivacaine for Cystoscopic Procedures
This study aims to compare the intrathecal injection of hyperbaric prilocaine 2% versus hyperbaric bupivacaine 0.5% in cystoscopy procedures.
- Conditions
- Intrathecal Injection, Hyperbaric Prilocaine, Hyperbaric Bupivacaine, Cystoscopic Procedures
- Trial name
- NCT07664618
- Testing
- Bupivacaine, Prilocaine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Spinal Anesthesia, Cardiac Toxicity
Cardiovascular Effects of Intrathecal Hyperbaric Prilocaine or Bupivacaine in Surgery Under Spinal Anesthesia
Spinal anesthesia remains a mainstay in lower limbs- as in day-case surgeries as well. It consists in injecting a local anesthetic drug into the intrathecal space of a patient's spinal canal.
- Trial name
- NCT05751148
- Testing
- Hyperbaric bupivacaïne, Hyperbaric prilocaïne
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Osteonecrosis
Randomized Controlled Trial of Hyperbaric Oxygen in Patients Who Have Taken Bisphosphonates
Osteonecrosis of the jaw (ONJ) has recently been recognized as associated with bisphosphonate therapy, however there is little information on the natural history, treatment or prevention strategies for this condition.
- Trial name
- NCT00462098
- Testing
- hyperbaric oxygen, non-treated control group
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Duke University
Hyperbaric Oxygen Therapy, Mild Cognitive Impairment
MRI Brain Changes Induced by Hyperbaric Oxygen Therapy in Brain Injury Patients
In our institute there is ongoing treatment of brain injury patients with Hyperbaric oxygen therapy. These patients undergo neuro-cognitive function tests in addition to brain imaging studies before and after treatment.
- Trial name
- NCT02452619
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Diabetic Foot Ulcers
Hyperbaric Oxygen, Oxidative Stress, NO Bioavailability and Tissue Oxygenation
Hyperbaric oxygen therapy (HBOT) increases tissue oxygenation and serves as an adjunct therapy for diabetic wounds. However, some patients have insufficient increase or even paradoxical decrease in tissue O2 due to…
- Trial name
- NCT00463671
- Testing
- N-acetylcysteine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Hearing Loss, Sudden, Prednisone Acetate
Treatment of Sudden Deafness With Prednisone+Hyperbaric Oxygen and Prednisone+Somatosensory Stimulation
To study the effective treatment of sudden deafness by giving prednisone, hyperbaric oxygen and somatosensory stimulation to sudden deafness patients.
- Conditions
- Hearing Loss, Sudden, Prednisone Acetate, Hyperbaric Oxygen, Somatic Stimulus
- Trial name
- NCT04129983
- Testing
- Drugs and Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Dan Su