Clinical trials: Hyperbaric
Cervical Incompetence in Pregnancy as Antepartum Condition
Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak.
- Trial name
- PRILOCC (NCT04394533)
- Testing
- Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%)
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Hyperbaric, Diving Medicine
Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air
Primary objective: Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air. Secondary objective: Assessment of fluid markers of central nervous system injury in blood post diving…
- Conditions
- Hyperbaric, Diving Medicine, Decompression Sickness, Central Nervous Injury
- Trial name
- NCT02468752
- Testing
- Oxygen, Air
- Where
- 2 sites in Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Diabetic Peripheral Vascular Disease
Measurement of Endothelial Function With Peripheral Arterial Tonometry in Patients Undergoing Hyperbaric Oxygen Therapy
The purpose of this clinical study is to test whether or not patients treated with HBOT for diabetic foot ulcers will demonstrate measurable changes of the blood vessel function during the course of HBOT treatments. , i.e.
- Trial name
- NCT02221466
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Ole Hyldegaard
Acute Thermal Burns
The Effects of Hyperbaric Oxygen Therapy (HBOT) on Acute Thermal Burns
The blinded RCTstudy aims to: Determine the effects of HBOT on burns conversion for patients who have fresh thermal burns injury using the LDI.
- Trial name
- NCT00824551
- Testing
- Hyperbaric Oxygen Therapy, Standard care
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Singapore General Hospital
Bone Marrow Transplantation, Hematopoietic Stem Cells
Hyperbaric Oxygen Therapy for Hematopoietic Progenitor Cell Collection in Poor Mobilizers
This is a pilot study to evaluate the efficacy of hyperbaric oxygen therapy (HBO2) for mobilizing hematopoietic progenitor cells from bone marrow to blood.
- Conditions
- Bone Marrow Transplantation, Hematopoietic Stem Cells, Multiple Myeloma, Lymphoma
- Trial name
- NCT02682953
- Testing
- Neupogen, Hyperbaric oxygen therapy, Plerixafor
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Disorder of Knee, Anesthesia
Spinal Anesthesia With Hyperbaric Levobupivacaine 0.75% for Ambulatory Knee Arthroscopy
The purpose of this study is to evaluate motor block probability throughout time and clinical profile when using three different doses of HLBP 0.75% (7.5, 9.37 and 11.25 mg) by a unilateral spinal block technique.
- Trial name
- levobupi (NCT01881087)
- Testing
- Hyperbaric Levobupivacaine 0.75%
- Where
- Colombia
- Volunteers
- 180 people
- Sponsor
- Fundacion Clinica Valle del Lili
Anesthesia, Obstetrical
Subarachnoid Bupivacaine in Obese Patients Undergoing Cesarean Delivery
This study evaluates the effect of subarachnoid hyperbaric bupivacaine on mean arterial blood pressure (MAP) of pregnant patients with obesity undergoing cesarean section half of the patients will receive subarachnoid hyperbaric…
- Trial name
- NCT04205344
- Testing
- Bupivacaine 5 mg, Bupivacaine 10 mg
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Civil de Guadalajara
Ear Barotrauma, Middle Ear Disease
Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury
- Trial name
- NCT04804098
- Testing
- Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
- Where
- United States
- Volunteers
- 1,553 people
- Sponsor
- Northwell Health
Diabetes Mellitus, Type II, Insulin Resistance
Insulin Sensitivity During Hyperbaric Oxygen Compared to Hyperbaric Air
In a recent series of studies performed by our group, we have shown that exposure to hyperbaric oxygen (HBO) leads to an increase in insulin sensitivity in male subjects with type-2 diabetes (T2DM) and in obese and overweight men…
- Trial name
- HOTAIR4 (NCT03138746)
- Testing
- HBO, Hyperbaric air
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- University of Adelaide
Osteonecrosis, Avascular Necrosis
Effect of HBOT on Femoral Head Avascular Necrosis (AVN)
The primary objective of this study is to determine whether the Hyperbaric Oxygen Therapy (HBOT) conducted under the Marx Protocol improves pain outcomes when combined with core decompression with autologous bone marrow aspirate…
- Trial name
- NCT06931301
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Yale University
Cerebral Necrosis
Adverse Radiation Effects After Gamma Knife Radio Surgery and Hyperbaric Oxygen Therapy
Evaluation of clinical improvement and the reduction of edema lesion documented by magnetic resonance imaging (MRI) in patients with cerebral radiation necrosis post gamma knife surgery (GKS) by treatment with hyperbaric oxygen…
- Trial name
- GKSHBO (NCT02714465)
- Testing
- hyperbaric oxygen therapy
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Niguarda Hospital
Cesarean Section; Shivering
Dosage of Intrathecal Hyperbaric Bupivacaine and the Incidence of Post Spinal Shivering.
Shivering is very common after spinal anaesthesia. Many studies have investigated the role of adding adjuvants to the local anaesthetics to decrease the incidence of post-spinal shivering.
- Trial name
- NCT03356899
- Testing
- Low dose bupivacaine 0.5% (8mg), High dose bupivacaine 0.5% (10mg)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy for Acute Domestic Carbon Monoxide (CO) Poisoning
Carbon monoxide poisoning still places a burden on the healthcare system worldwide. While oxygen therapy is the cornerstone treatment, the role and practical modalities of hyperbaric oxygen therapy (HBO) remain controversial.
- Trial name
- NCT01100515
- Testing
- normobaric oxygen therapy, Hyperbaric oxygen therapy
- Where
- France
- Volunteers
- 179 people
- Sponsor
- University of Versailles
Hyperbaric Oxygen Therapy, Stroke
The Effectiveness of Hyperbaric Oxygen Therapy on Pneumonia Complicating Stroke
To investigate the evidence for the integration of hyperbaric oxygen therapy (HBOT) as part of interdisciplinary stroke rehabilitation.
- Conditions
- Hyperbaric Oxygen Therapy, Stroke, Pneumonia
- Trial name
- NCT04376359
- Testing
- hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Ya Zhang
Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl
A Comparative Study on Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl for Optimal Dose to be Used in Elderly Patients Undergoing Day Case Lower Abdominal and Urologic Surgeries.
To compare the effects of using different doses of intrathecal hyperbaric prilocaine 2% combined with fentanyl 25 µg in patients scheduled for a day-case lower abdominal and urologic surgery in the geriatric patient population.
- Trial name
- NCT05726968
- Testing
- Pilocaine 2% (1.5 ml) and 25 ug fentany
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyperbaric Oxygen Therapy, Middle Ear Barotrauma
Effect of Self-acupressure on Middle Ear Barotrauma Associated With Hyperbaric Oxygen Therapy
Middle ear barotrauma (MEB) is the most common complication during hyperbaric oxygen therapy (HBOT). Though Valsalva and Toynbee maneuvers have been proposed to prevent MEB, still some patients discontinue HBOT due to severe…
- Trial name
- NCT04311437
- Testing
- Self-acupressure therapy, Combined Valsalva and Toynbee maneuvers
- Where
- Taiwan
- Volunteers
- 152 people
- Sponsor
- Chang Gung Memorial Hospital
Crush Injury
Use of Hyperbaric Oxygen Therapy for the Treatment of Crush Injuries
The purpose of this study is to determine whether using hyperbaric oxygen (HBO) improves wound healing for patients who have a crush injury.
- Trial name
- NCT04049721
- Testing
- HBO, Standard of Care
- Where
- United States
- Sponsor
- NYU Langone Health
Healthy, CVA
Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.
DELPhI software developed for the analysis of EEG recordings in response to magnetic stimulation in relation to clinical data.
- Conditions
- Healthy, CVA, Hemorrhage, TBI (Traumatic Brain Injury)
- Trial name
- NCT04095377
- Testing
- No intervention, this is a retrospective study.
- Where
- Israel
- Volunteers
- 875 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Wound, Biofilm
Clinical Implications of Biofilm in Chronic Wound
Chronic wounds are important economic and health-care problem. Biofilm has been recognized as a major factor in wound chronicity, delayed healing, and persistent infections, increasing the need for frequent dressing changes…
- Conditions
- Wound, Biofilm, Chronic Pain, Quality of Life
- Trial name
- NCT05054244
- Testing
- standard wound treatment, Hyperbaric oxygenation (HBOT)
- Where
- Croatia
- Volunteers
- 140 people
- Sponsor
- University of Rijeka