Clinical trials: Hyperbaric Oxygenation
Acute Ischemic Stroke
Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Ischemic Stroke Recovery (Pro00061930)
This study will critically examine the feasibility, safety and efficacy of HBOT during inpatient rehabilitation (IPR) after acute ischemic stroke measured by non-disruption of 3 hours of daily therapy, frequency of neurological…
- Trial name
- NCT06148285
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- LCMC Health
Laryngeal Cancer
Efficacy of Hyperbaric Oxygen Therapy in Laryngectomy Patients
This study is designed to develop a predictive model for the development of wound complications in patients undergoing laryngectomy surgery for laryngeal/adjoining structure cancers, and to evaluate the clinical efficacy of…
- Trial name
- NCT00026975
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cerebral Necrosis
Adverse Radiation Effects After Gamma Knife Radio Surgery and Hyperbaric Oxygen Therapy
Evaluation of clinical improvement and the reduction of edema lesion documented by magnetic resonance imaging (MRI) in patients with cerebral radiation necrosis post gamma knife surgery (GKS) by treatment with hyperbaric oxygen…
- Trial name
- GKSHBO (NCT02714465)
- Testing
- hyperbaric oxygen therapy
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Niguarda Hospital
Fibromyalgia, Emotional Trauma
Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma
The investigators have previously studied the efficacy of hyperbaric oxygen therapy (HBOT) as a treatment for Fibromyalgia syndrome (FMS) in a prospective, active control, crossover clinical trial.
- Trial name
- NCT04316702
- Testing
- Hyperbaric oxygen therapy (HBOT) treatment, Cymbalta / Lyrica - Drug treatment
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Assaf-Harofeh Medical Center
Breast Cancer, Lung Metastasis
Concept-verification Clinical Trial on the Inhibition of Breast Cancer Lung Metastasis Progression by Hyperbaric Oxygen
This is a proof-of-concept clinical trial focused on exploring whether hyperbaric oxygen therapy (HBOT) can inhibit the progression of lung metastasis in breast cancer patients.
- Conditions
- Breast Cancer, Lung Metastasis, Hyperbaric Oxygen Therapy
- Trial name
- HBOIBCLM (NCT07514728)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jinan Central Hospital
Anterior Cruciate Ligament Reconstruction
The Effect of Hyperbaric Oxygen Therapy for Acceleration Recovery After Anterior Cruciate Ligament Reconstruction(ACLR)
The aim of the current study is to evaluate the effect of HBOT for acceleration recovery after ACLR.
- Trial name
- NCT06493851
- Testing
- hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Carbon Monoxide Poisoning, Hyperbaric Oxygenation
Prognostic Biomarkers in CO Poisoning
Mitochondrial and oxidative stress participate in the pathogenic mechanisms of carbon monoxide (CO)-induced toxicity. Thus, serum indicators of mitochondrial and oxidative stress could be useful for predicting neurocognitive…
- Conditions
- Carbon Monoxide Poisoning, Hyperbaric Oxygenation, Biomarkers
- Trial name
- NCT05088005
- Testing
- Hyperbaric oxygen therapy
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Wonju Severance Christian Hospital
Hyperbaric Oxygen Therapy
Measuring Cognitive Enhancement During Hyperbaric Oxygen Treatments
The aim of the current study was to examine the effect of short-term HBOT (hyperbaric oxygen treatments) on a range of cognitive abilities.
- Trial name
- NCT04358796
- Testing
- Hyperbaric oxygent treatment, Control hyperbaric oxygen treatment
- Where
- Israel
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Type 2 Diabetes Mellitus
Autologous Stem Cell and Hyperbaric Oxygen Therapy in Type 2 Diabetes Mellitus
A prospective, open labeled, randomized controlled clinical trial comparing the benefit of both hyperbaric oxygen therapy and intrapancreatic stem cell infusion to standard medical treatment alone for type 2 diabetes mellitus.
- Trial name
- HOT (NCT01786707)
- Testing
- Autologous stem cells, Hyperbaric oxygen therapy, Insulin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Rodolfo Alejandro
Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms
Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker Study
The goal of this study is to examine changes in blood biomarkers following hyperbaric oxygen therapy (HBOT) in military veterans with traumatic brain injury and persistent post-concussive symptoms.
- Conditions
- Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms, PTSD
- Trial name
- NCT07849465
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Summit Hyperbarics and Wellness
Diabetic Peripheral Vascular Disease
Measurement of Endothelial Function With Peripheral Arterial Tonometry in Patients Undergoing Hyperbaric Oxygen Therapy
The purpose of this clinical study is to test whether or not patients treated with HBOT for diabetic foot ulcers will demonstrate measurable changes of the blood vessel function during the course of HBOT treatments. , i.e.
- Trial name
- NCT02221466
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Ole Hyldegaard
Post-Concussion Syndrome
Hyperbaric Oxygen Therapy for Post-Concussion Syndrome
The purpose of this study is to decrease symptom burden, improve cognitive function, and improve quality of life outcomes in subjects with mild TBI and persisting post-concussion syndrome using Hyperbaric Oxygen Treatment…
- Trial name
- NCT05643482
- Testing
- Hyperbaric Oxygen Treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Texas Southwestern Medical Center
Carotid Stenosis, Cognitive Impairment
Cognitive Improvement After Carotid Stenting in Hyperbaric Oxygen Therapy Trial
The purpose of CARE-HBOT study is to evaluate whether patients with symptomatic severe carotid artery stenosis with cognitive impairment who underwent hyperbaric oxygen therapy plus standard medical treatment after stent…
- Conditions
- Carotid Stenosis, Cognitive Impairment, Hyperbaric Oxygen Therapy, Stent Implantation
- Trial name
- NCT05980195
- Testing
- Hyperbaric oxygen therapy, Standard medical treatment, Risk factor management
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Cognitive Decline, COVID-19
Hyperbaric Oxygen Therapy Improves Brain Function in Patients With Cognitive Decline After COVID-19 Infection.
COVID-19 has swept the world, and while some people may experience long-term cognitive decline as a result of infection, no effective treatment has been announced.
- Conditions
- Cognitive Decline, COVID-19, SARS CoV 2 Infection
- Trial name
- NCT05715801
- Testing
- hyperbaric oxygen therapy, conventional oxygen therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant
The purpose of this study is to determine if hyperbaric oxygen therapy is safe in the setting of stem cell transplantation. This study will also determine if hyperbaric oxygen therapy improves engraftment, graft versus host…
- Conditions
- Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia
- Trial name
- NCT03964506
- Testing
- Hyperbaric oxygen
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Omar Aljitawi
Late Radiation Injury, Chronic Pain
HBOT Late Radiation Tissue Injury
Background: Radiotherapy is a common treatment for many malignancies. Radiation-related complications developing months or years after radiation treatment are known as late radiation tissue injury (LRTI) and are estimated to…
- Trial name
- NCT02425215
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Cognition
Effects of Hyperbaric Oxygen Therapy on Cognitive Function on Autistic Spectrum Disordered Children
HYPOTHESIS 1. Hyperbaric Oxygenation Therapy will be safe to use with neurotypical adults and children. 2. Hyperbaric Oxygenation Therapy will have a statistically significant positive effect on measures of cognitive function in…
- Trial name
- NCT00631215
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pediatric Partners of Ponte Vedra
Bladder Cancer, Cervical Cancer
Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer
RATIONALE: Radiation therapy can cause long-term adverse effects. Hyperbaric oxygen therapy may be effective in lessening gastrointestinal symptoms caused by radiation therapy given for pelvic cancer.
- Conditions
- Bladder Cancer, Cervical Cancer, Colorectal Cancer, Endometrial Cancer
- Trial name
- NCT01087268
- Testing
- questionnaire administration, gastrointestinal complications management/prevention, quality-of-life assessment
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Insulin Resistance Syndrome
Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause
Background: In postmenopausal females, Insulin resistance is commonly encountered in clinical setting. Hyperbaric oxygen therapy have been proposed effective in lowering blood glucose level and improving function.
- Trial name
- NCT06806345
- Testing
- Hyperbaric oxygen therapy, Hypoglycemic Drug
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
T1DM
Efficacy of Hyperbaric Oxygen Therapy (HBOT) in New-onset Type-1 Diabetes Mellitus
Type 1 Diabetes Mellitus (T1DM) is caused by an autoimmune process that progressively destroys the pancreatic β-cells, and leads to dependence on multiple daily insulin subcutaneous injections according to glucose measurements…
- Trial name
- NCT04412200
- Testing
- Hyperbaric oxygen chamber (HBOC)
- Where
- 2 sites in Israel
- Volunteers
- 36 people
- Sponsor
- Assaf-Harofeh Medical Center