Clinical trials: Hyperchloremia
Patients Undergoing Cardiothoracic Surgery
Limiting IV Chloride to Reduce AKI After Cardiac Surgery
This primary aim of this study is to test the impact of a strategy of perioperative chloride-restriction through intravenous (IV) fluid therapy on the incidence of acute kidney injury after cardiac surgery.
- Trial name
- LICRA (NCT02020538)
- Testing
- Low-chloride perioperative intravenous fluid strategy, High-chloride perioperative intravenous fluid strategy
- Where
- Australia
- Volunteers
- 1,298 people
- Sponsor
- Bayside Health
Critical Care, Hyperchloremia
Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke
Normal saline (0.9% sodium chloride), a classical crystalloid solution, is widely used to maintain fluid balance, volume resuscitation and dilute drugs during clinical practice.
- Conditions
- Critical Care, Hyperchloremia, Hemorrhagic Stroke
- Trial name
- MERIT (NCT06374823)
- Testing
- Multiple Electrolyte, Normal Saline
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Capital Medical University
Normal Anion Gap Metabolic Acidosis
Ringer's Lactate Versus Normal Saline in Caesarean Section
The objective of this study is to compare the effect on mean maternal and neonatal pH, and 24-hour postoperative morbidity, following intraoperative infusion of Ringer's Lactated versus normal saline in caesarean section at…
- Trial name
- NCT01585740
- Testing
- 0.9% Normal Saline, Ringer's Lactate
- Where
- Uganda
- Volunteers
- 500 people
- Sponsor
- Makerere University
Hyperchloremic Acidosis, Transurethral Resection of Prostate
Effects of Isotonic Saline As Irrigation Fluid In Transurethral Resection of Prostate (TUR-P) Operations
Benign hypertrophy of the prostate (BPH) is a disease seen in 20% of men over the age of 50 and in 40% of those over the age of 70.
- Conditions
- Hyperchloremic Acidosis, Transurethral Resection of Prostate, Normal Anion Gap Metabolic Acidosis, Anesthesia
- Trial name
- NCT05285189
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University
Stroke, Acute
Best Solution Identification to Prevent Hyperchloremia Combinations of Sodium Chloride and Sodium Acetate IV Fluids Along With Standard of Care Treatment in Acute Stroke Patients
Hypothesis: Hyper chloremia is associated with poor outcome in Intracerebral Hemorrhage (ICT). Hyperchloremia is defined as serum chloride level of 110mmol/L or greater.
- Trial name
- sodium acetate (NCT05869565)
- Testing
- Sodium Chloride 0.9% infusion alone or in combination with Sodim acetate with normal saline in a ratio 1;1, 2;1 and 3;1
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Aga Khan University
HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia
Metabolic and Clinical Effects of Hyperchloremia During HoLEP Surgery.
This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change.
- Conditions
- HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia, Perioperative Management
- Trial name
- NCT07655830
- Testing
- HoLEP surgery
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Aneurysmal Subarachnoid Hemorrhage, Hyperchloremia
Impact of Multiple Electrolytes Injection Ⅱ and Saline on Hyperchloremia in Patients With Aneurysmal Subarachnoid Hemorrhage:a Pilot Study
The goal of this pilot randomized trial is to compare the effect of Multiple Electrolytes Injection Ⅱand saline on the occurrence of hyperchloremia within 72h of randomization in patients with aneurysmal subarachnoid…
- Trial name
- NCT06076590
- Testing
- maintenance fluid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Septic Shock, Shock
Balanced Crystalloid vs. Saline in Children With Septic Shock
Fluid resuscitation is the cornerstone of pediatric shock management; current practices of fluid resuscitation in children are not evidence based.
- Trial name
- NCT02835157
- Testing
- Balanced crystalloid solution, 0.9%sodium chloride
- Where
- 4 sites in India
- Volunteers
- 708 people
- Sponsor
- All India Institute of Medical Sciences
Congenital Diaphragmatic Hernia, Acute Kidney Injury
Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia
The main aim of this project is to elucidate the incidence of acute kidney injury (AKI) in newborns with congenital diaphragmatic hernia during stay in the Pediatric intensive care unit. (PICU).
- Conditions
- Congenital Diaphragmatic Hernia, Acute Kidney Injury, Multiple Organ Failure, Pulmonary Hypertension
- Trial name
- NCT06050525
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Karolinska Institutet
Diabetic Ketoacidosis
Double Blinded Randomized Control Trial of Types of IVF in Children With DKA
Objectives: Intravenous (IV) fluid administration is a fundamental component of diabetic ketoacidosis (DKA) treatment. Normal saline (NS), the most common IV fluid used in DKA management, contains more chloride than human blood.
- Trial name
- NCT03066440
- Testing
- Normal saline, Lactated Ringers
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- State University of New York at Buffalo