Clinical trials: Hyperdynamic
Septic Shock Hyperdynamic
ILOPROST in Septic Shock With Persistent Microperfusion Defects (I-MICRO)
Septic shock remains a major cause of death in critically ill patients. Alterations in microcirculation have long been proposed as a key pathophysiological factor of organ dysfunction and death in septic shock patients.
- Trial name
- I-MICRO (NCT03788837)
- Testing
- ILOPROST, NaCl
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wrinkles
Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles
To evaluate the safety and effectiveness of the iovera° device with the blunt tip cannula for the treatment of forehead wrinkles.
- Trial name
- NCT01984619
- Testing
- Cryotherapy for the utilization of wrinkle reduction (iovera)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Cardiac Ultrasound Phenotypes, Septic Myocardial Suppression
A Multicenter Cross-sectional Study of Cardiac Ultrasound Phenotypes in Patients With Sepsis
The heart, one of the most important organs for oxygen supply and consumption, is frequently involved in sepsis, i.e. septic cardiomyopathy, also known as septic myocardial suppression.
- Conditions
- Cardiac Ultrasound Phenotypes, Septic Myocardial Suppression, Hyperdynamic State Left Ventricular Function in Sepsis Patients, Outcome
- Trial name
- NCT05161104
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fujian Provincial Hospital
Trauma, Sepsis
The Relation Between the Renal Resistive Index and Glomerular Hyper Filtration
Aim of the present study is to determine whether 1. RRI can predict glomerular hyperfiltration; 2. glomerular hyperfiltration is associated with low renal resistive index; 3.
- Trial name
- NCT02560402
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Amsterdam UMC, location VUmc
Hyperdynamic, Left Ventricular Ejection Fraction
Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic Shock
The study aimed to evaluate the cause and prognosis of hyperdynamic left ventricular ejection fraction in critically ill patients with sepsis.
- Conditions
- Hyperdynamic, Left Ventricular Ejection Fraction, Mortality, Intensive Care Unit
- Trial name
- NCT06993948
- Testing
- Transthoracic echocardiography
- Where
- Egypt
- Volunteers
- 235 people
- Sponsor
- Ain Shams University
Blepharospasm, Hemifacial Spasm
Post Marketing Surveillance Study of Dysport
The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.
- Conditions
- Blepharospasm, Hemifacial Spasm, Cervical Dystonia, Spasmodic Torticollis
- Trial name
- NCT00210431
- Where
- 36 sites in France, Germany and 1 more
- Volunteers
- 783 people
- Sponsor
- Ipsen
Shock, Septic
Effect of a Continuous Infusion of Esmolol on Stroke Volume in Patients With Hyperdynamic Vasoplegic Septic Shock
The main objective of this study is to evaluate the effectiveness of the administration of a short acting beta-blocker in terms of effective increase in stroke volume (at least 15%) after 4 hours initiation of therapy in septic…
- Trial name
- BétaSep (NCT02609152)
- Testing
- Continuous perfusion of esmolol, Continuous perfusion of saline
- Where
- 2 sites in France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cough, Hypertension
Optimal Remifentanil Ce for Preventing Severe Cough and Hyperdynamic Response During Tracheal Extubation
Pain, cough, hypertension and tachycardia are frequent events during extubation due to a secondary stimulation of mechanoreceptors located in the airway.
- Trial name
- REX (NCT03132519)
- Testing
- Remifentanil
- Where
- Colombia
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili
Septic Shock Hyperdynamic
Acetated Ringer's Solution Versus Saline in Patients With Septic Shock
The primary aim of this trial is to compare the effect of acetated ringer's solution with that of saline for therapy on the incidence and development of major adverse renal events among septic shock patients.
- Trial name
- NCT04507672
- Testing
- Fluid resuscitation
- Volunteers
- 2,000 people
- Sponsor
- Southeast University, China
Liver Transplantation
Hemodynamic Measurements During Liver Transplantation
The purpose of the study is to determine if the less invasive monitors are as reliable for measuring heart function in patients undergoing liver transplantation as the more invasive pulmonary artery.
- Trial name
- OLT (NCT00682110)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Cerebral Vasospasm
Milrinone in Addition to Hyperdynamic Therapy in the Treatment of Vasospasm Following Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to evaluate the usefulness of adding Milrinone to the current standard treatment for cerebral vasospasm.
- Trial name
- NCT02712788
- Testing
- Milrinone
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Trachebronchomalacia (TBM), Hyper Dynamic Airway Collapse (HDAC)
Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea
The investigators hypothesize that there is a strong correlation between OSA and TBM/HDAC. Our hypothesis is based on the similarities in mechanism (airway collapse), symptoms (daytime and nocturnal dyspnea) predisposing…
- Conditions
- Trachebronchomalacia (TBM), Hyper Dynamic Airway Collapse (HDAC), Obstructive Sleep Apnea (OSA)
- Trial name
- NCT02097212
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Jewish Health