Clinical trials: Hyperferritinemia
Dysmetabolic Syndrome, Hyperferritinemia
Respiratory Variations for Assessing Blood Withdrawal 2
OBJECTIVES: To investigate whether respiratory variations of the inferior vena cava (ΔIVC) and internal jugular vein (ΔIJV) diameters during standardized breathing (ΔIVCST and ΔIJVST) increase after a therapeutic bleeding in…
- Conditions
- Dysmetabolic Syndrome, Hyperferritinemia, Obese
- Trial name
- ReVAs2 (NCT03066401)
- Testing
- echography
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Lille
Hemochromatosis, Type 4, Ferroportin Disease
Analysis of the Modulation of Serum Hepcidin Level in Response to Iron Oral Intake: Potential Interest for the Differential Diagnosis Between Ferroportin Disease and Dysmetabolic Hepatosiderosis.
The diagnosis of iron overload is a common problem. It is important to optimize the diagnosis to ensure support for patients and their relatives especially regarding genetic disease.
- Conditions
- Hemochromatosis, Type 4, Ferroportin Disease, Dysmetabolic Hepatosiderosis, Diagnosis
- Trial name
- NCT01949467
- Testing
- iron fumarate
- Where
- 4 sites in France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Lymphohistiocytosis, Hemophagocytic, Secondary Hemophagocytic Lymphohistiocytosis
Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study
Background: Hemophagocytic lymphohistiocytosis (HLH) is a disease caused by disrupted immune function. People with HLH are prone to fevers and illnesses, which can be fatal.
- Conditions
- Lymphohistiocytosis, Hemophagocytic, Secondary Hemophagocytic Lymphohistiocytosis, Macrophage Activation Syndrome, Hyperinflammatory Syndromes
- Trial name
- NCT06339177
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hyperferritinemia
Candidate Gene for Hyperferritinemia
Ferritin is a ubiquitous protein capable of storing iron in the cell cytosol. Stored iron is released and made available for cellular needs by the degradation of ferritin itself.
- Trial name
- HyFerr (NCT05659017)
- Testing
- Genetic analysis
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Milano Bicocca
Critical Illness, Sepsis
Hyperinflammation and Hyperferritinemia in Critically Ill Patients
Analysing trajectory of critically ill patients with signs of hyperinflammation
- Conditions
- Critical Illness, Sepsis, Hyperferritinemia, Hyperinflammatory Syndrome
- Trial name
- HYFER (NCT06820905)
- Where
- Czechia
- Volunteers
- 1,962 people
- Sponsor
- Charles University, Czech Republic
Hyperferritinemia, Hypertriglyceridemia
Effect of Therapeutic Phlebotomies on the Triglycerides Concentration in Patients With Hypertriglyceridemia and Hyperferritinemia
The purpose of this study is to evaluate the effect of iron depletion with phlebotomies on blood triglyceride concentration, in subjects with hypertriglyceridemia and iron overload, compared with a dietary intervention alone.
- Trial name
- NCT02526121
- Testing
- Phlebotomy, Dietary and lifestyle counseling.
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Hereditary Hemochromatosis, Hyperferritinemia
Quality and Biologic Characteristics of Red Blood Concentrates Obtained From Individuals With Elevated Ferritin.
Iron overload in hereditary hemochromatosis (HH) is treated by phlebotomy. It is unclear, if individuals with hyperferritinemia due to hereditary hemochromatosis or to secondary causes are suitable as blood donors.
- Trial name
- NCT05742035
- Testing
- Venipuncture
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Interregionale Blutspende SRK