Clinical trials: Hyperglycaemia
Glucose Intolerance, Insulin Resistance
Iron and Insulin Resistance in Overweight and Obese Humans
Determine the effects of reducing whole-body iron stores in overweight/obese subjects (via one-time blood donation) on adipose tissue iron content, factors regulating iron homeostasis and lipolytic rate in adipose tissue, as well…
- Conditions
- Glucose Intolerance, Insulin Resistance, Iron Metabolism
- Trial name
- Fe (NCT03348020)
- Testing
- Blood Donation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus, Type 2, Hyperglycemia, Postprandial
Exercise-meal Timing and Postprandial Glucose Control
Physical activity helps maintain optimal postprandial blood glucose control. However, there is a lack of clear information regarding the optimal meal-activity timing required to maximize blood glucose control.
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia, Postprandial, Physical Activity, Glucose Intolerance
- Trial name
- NCT03730727
- Testing
- Physical activity, Meal
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Pre-diabetes, Obese
Investigation of an Amino Acid Supplement on Glucose Levels in Obese Subjects
This study aims to determine whether the use of Branched-Chain Amino Acids (BCAA's) regulate insulin and glucagon secretion, and whether the supplement has any effect on body weight and body composition.
- Conditions
- Pre-diabetes, Obese, Glucose Intolerance
- Trial name
- NCT03715010
- Testing
- BCAA
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Infant Conditions, Glucose Intolerance
Monitoring of Postprandial Glycemic Variability in Healthy Young Infants
To measure and quantify the postprandial glucose variations in response to a meal in the healthy 6-12 months old child and correlate this response with the composition of this meal.
- Trial name
- IGVM (NCT03819725)
- Testing
- Glucose monitoring
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY
Postprandial Hyperglycemia, Postprandial Insulin
Individually Timed Stair Climbing and Descending to Lower Postprandial Glucose
Effect of individually timed exercise to attenuate postprandial glucose excursions
- Trial name
- NCT05405010
- Testing
- Stair climbing and descending for 1 minute, Stair climbing and descending for 3 minutes, Seated control
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Endometrial Cancer
Study of Insulin Resistance and Endometrial Cancer in Harris County, Texas
The goal of this clinical research study is to find out if there is a link between insulin resistance (or pre-diabetes) and endometrial cancer. Primary Objective: 1.
- Trial name
- NCT00495235
- Testing
- Questionnaire
- Where
- 8 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gestational Diabetes, Hyperglycemia
Gestational Metabolic Abnormalities and Maternal and Infant Nutrition and Health
Childhood obesity is on the rise and is a major risk factor for type 2 diabetes later in life. Recent evidence indicates that abnormalities that increase risk for diabetes may be initiated early in infancy.
- Conditions
- Gestational Diabetes, Hyperglycemia, Insulin Resistance, Obesity
- Trial name
- NCT01405547
- Where
- Canada
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Anthony Hanley
Steroid-Induced Diabetes, Diabete Type 2
Predictive Factors and Monitoring Strategies in Steroid-Induced Diabetes
Glucocorticoids are widely used in the management of autoimmune, inflammatory and neoplastic conditions. However, they are associated with significant metabolic effects, including steroid-induced diabetes (SID).
- Conditions
- Steroid-Induced Diabetes, Diabete Type 2, Steroid Induced Hyperglycemia
- Trial name
- NCT07190378
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Pre-diabetes, Obesity
Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls
Aims: 1. Does inflammation contribute importantly to concurrent defects in vascular and metabolic dysfunction in human pre-diabetic obesity? 2.
- Trial name
- NCT00837590
- Testing
- Chronic salsalate, Acute Salsalate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Indiana University
Impaired Glucose Tolerance
Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance
The objective is to identify the lowest effective dose of Grape Seed Extract (GSE) on glucose control in people with impaired glucose tolerance (IGT).
- Trial name
- GSE3 (NCT02254317)
- Testing
- 300 mg GSE, 600 mg GSE, 900 mg GSE
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Hyperglycemia, Hyperglycemia, Postprandial
NUTRACORE, Glycaemic Index and Appetite
In recent decades, the world prevalence of obesity and type 2 diabetes (DMT2) has increased dramatically, resulting in a global epidemic.
- Conditions
- Hyperglycemia, Hyperglycemia, Postprandial, Appetitive Behavior, Hyperinsulinism
- Trial name
- NTRCR-vivo (NCT05528874)
- Testing
- Same intervention for both groups: glycaemic index assessment of 3 biscuits recipes, Crossover: Recipe 4 before recipe 5, Crossover: Recipe 5 before recipe 4
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Impaired Glucose Tolerance
Effects of Artificial Sweeteners on Gut Microbiota and Glucose Metabolism
The Objectives of this study is to determine the effect(s) of daily non-caloric artificial sweetener (NAS) consumption (sucralose or aspartame) on the composition of the bacteria and also to determine the changes in glucose…
- Trial name
- NCT02569762
- Testing
- Sucralose-Aspartame, Aspartame-Sucralose
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hyperglycaemia (Diabetic), Healthy Volunteers
The Assessment of Single-Dose Safety,Tolerability, Pharmacokinetics and Pharmacodynamic of Globalagliatin Hydrochloride
This is a phase 1 randomized,double-blind,placebo-controlled study with single oral dose of globalagliatin hydrochloride (SY-004) administered to chinese healthy subjects to evaluated the safety, tolerability, pharmacokinetics…
- Trial name
- NCT03171623
- Testing
- globalagliatin hydrochloride
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Yabao Pharmaceutical Group
Abdominal Obesity, Insulin Resistance
The Effect of Nordic Recommended Diet on the Features of Metabolic Syndrome - Multicentre Study
SYSDIET (Systems biology in controlled dietary interventions and cohort studies) is one of the three centres in the NCoE Food, Nutrition and Health, 2007-2011.
- Conditions
- Abdominal Obesity, Insulin Resistance, Impaired Glucose Tolerance, Type 2 Diabetes
- Trial name
- SYSDIET (NCT00992641)
- Testing
- Experimental diet, Control diet
- Where
- 8 sites in Denmark, Finland and 3 more
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Hyperglycemia
Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins
Anesthetic preconditioning (APC, a brief exposure to an anesthetic gas) has become an area of intense research interest because of its ability to protect tissue and organs from injury resulting from a cessation of blood flow and…
- Trial name
- NCT00995670
- Testing
- 5% dextrose, Vitamin C, Simvastatin
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hyperglycemia
Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults
This study tested the effects of resistant starch type 4 on blood sugar and hunger in young adults with Type 2 diabetes.
- Trial name
- NCT00687960
- Testing
- Resistant starch type 4 - raw, Resistant Starch Type 4 - Cooked, Dextrose
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Pancreatectomy; Hyperglycemia, Diabete Mellitus
Glucose Metabolism After Partial Pancreatectomy
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Trial name
- NCT04409171
- Testing
- oral glucose tolerance test
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hyperglycaemia, Hypertension
Developing an AI Pharmacy Chatbot for the Population of Hong Kong
The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate…
- Conditions
- Hyperglycaemia, Hypertension, Hyperlipidaemia, Artificial Intelligence (AI)
- Trial name
- NCT07037563
- Testing
- An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia
- Where
- 2 sites in Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prediabetes, Hyperglycemia
Benefit of IQP-VV-102 in Reducing Postprandial Glucose Level in Overweight Caucasian Subjects
In this trial, the investigational product , the active ingredients which has been proven to reduce postprandial glucose in healthy and diabetic patients, will be tested.
- Trial name
- NCT02541344
- Testing
- Dose 1 of IQP-VV-102, Dose 2 of IQP-VV-102
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- InQpharm Group