Clinical trials: Hyperglycemias
Chronic Renal Failure
Effects of Cyclosporine A on Pancreatic Insulin Secretion
Our primary aim is to investigate if cyclosporine A reduces insulin secretion.
- Trial name
- NCT00139035
- Testing
- cyclosporine A
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- University of Oslo School of Pharmacy
Obesity, NAFLD
Low-Calorie Diet in People With Prediabetes/Metabolic Syndrome
Significant weight reduction, achieved by low-calorie diet (LCD), will mobilise ectopic fat (visceral and particularly liver fat), improving insulin sensitivity and other metabolic syndrome components, with secondary beneficial…
- Conditions
- Obesity, NAFLD, Fatty Liver, Pre Diabetes
- Trial name
- CALIBRATE (NCT04786418)
- Testing
- Standard of care, Low-calorie diet
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Ketosis Prone Diabetes, Diabetes Ketoacidosis
Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin Treatment
The study intends on enrolling 48 subjects with diabetes. Diabetic subjects that no longer need insulin will be randomly placed (like the flip of a coin) on a diabetes pill called metformin, a diabetes pill called sitagliptin or…
- Conditions
- Ketosis Prone Diabetes, Diabetes Ketoacidosis, Hyperglycemia
- Trial name
- NCT01099618
- Testing
- metformin, Sitagliptin
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dawn Smiley MD
Postprandial Hyperglycemia
The Acute Effect of Moderate Intensity Stair-Climbing on Postprandial Blood Glucose
This study aims to investigate the effect of moderate intensity stair-climbing bouts of various durations on postprandial blood glucose.
- Trial name
- NCT03400774
- Testing
- Stair-climbing
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Diabetes, Physical Activity
Feasibility of REHIT in NDH Patients
The aim of this feasibility study was to describe and report data relevant to the acceptability of an exercise intervention (reduced-exertion, high-intensity interval training) in non-diabetic hyperglycaemia patients delivered in…
- Trial name
- NCT04011397
- Testing
- Exercise intervention, Usual care
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Huddersfield
Insulin Resistance, Impaired Glucose Tolerance
The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults
This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are: 1.
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, Obesity, Metabolic Disturbance
- Trial name
- NCT05912348
- Testing
- Low Physical Activity and Added Carbohydrate Group, Low physical Activity Control, High Physical Activity and Added Carbohydrate Group
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Stress Hyperglycemia
Stress Hyperglycemia and Acute Ischemic Stroke
Whereas diabetes mellitus is clearly a risk factor for the occurrence of stroke and for its poor prognosis, hyperglycemia per se is also linked to increased morbidity and mortality in stroke patients.Therefore, the objective of…
- Trial name
- NCT04408768
- Testing
- standard protocol for stroke patients
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Pre-Diabetes
BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes
This is a single-centre, 16-week, randomized, double-blind, placebo-controlled, 3-treatment arm pilot study to evaluate the efficacy and safety of BTI320 in the treatment of high risk subjects with pre-diabetes.
- Trial name
- NCT02358668
- Testing
- BTI320
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Septic Shock, Adverse Event
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with.
- Conditions
- Septic Shock, Adverse Event, Hydrocortisone, Hyperglycemia
- Trial name
- CESSHYDRO (NCT05818826)
- Testing
- normal saline solution, Hydrocortisone and normal saline solution
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Critical Illness, Hyperglycemia
Comparing Two Ways of Controlling Blood Sugar With Insulin in Patients Admitted to the Intensive Care Unit
The purpose of this study is to determine if there is any difference between two ways of controlling blood sugar with insulin. In patients admitted to the intensive care unit, blood sugar levels often rise due to the stress of…
- Trial name
- NCT00166491
- Testing
- Insulin
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- Mayo Clinic
Hyperglycemia, Hyperglucagonemia
Glucagon-Like Peptide-1 (GLP-1) Suppression of Alpha Cell Secretion in Type 2 Diabetes Mellitus (T2DM)
The incretin hormone glucagon-like peptide-1 (GLP-1) has known insulinotrophic and glucagonostatic properties. However, inpatients with type 2 diabetes mellitus (T2DM)it is shown, that the beta cell sensitivity towards GLP-1 is…
- Conditions
- Hyperglycemia, Hyperglucagonemia, Glucose Intolerance
- Trial name
- NCT00862589
- Testing
- GLP-1 infusion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Pre-Diabetes
Designer Functional Foods on Parameters of Metabolic and Vascular in Prediabetes
This is a multi-site, double-blind, randomized, controlled food intervention study being conducted at the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM) in Winnipeg and the Mayo Clinic, Rochester, MN, to…
- Trial name
- PREFFER-2014 (NCT02400450)
- Testing
- Functional Ingredient Group, Control Ingredient Group
- Where
- 2 sites in United States, Canada
- Sponsor
- University of Manitoba
Hypertension, Hyperlipidemias
Clinical Trials of Two Helichrysum Infusions in Adults
The study evaluates the effects of Helichrysum italicum and Helichrysum Arenarium on different components of the metabolic syndrome.
- Conditions
- Hypertension, Hyperlipidemias, Inflammation, Hyperglycemia
- Trial name
- SMILJ (NCT04866628)
- Testing
- Helichrysum italicum infusion, Helichrysum arenarium
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Type I Diabetes
Effects of Capros in Patients With Type-1 Diabetes
The purpose of this 12 week longitudinal study is to test the effect of the dietary supplement, Capros, on blood glycemic index of Type 1 diabetics that have a sensor that provides continuous glucose monitoring (CGM).
- Trial name
- CarposT1D (NCT02634216)
- Testing
- Capros
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University
Type 1 Diabetes (T1D), Pre Diabetes
INNODIA Family & Friends Early-Stage T1D Detection Protocol
The purpose of INNODIA DETECT is to identify people who are at increased risk of developing T1D. Investigators are doing this by testing for markers in the blood (autoantibodies) that tell them an individuals risk of getting T1D…
- Trial name
- INNODIA DETECT (NCT07118098)
- Where
- 21 sites in Austria, Belgium and 6 more
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- INNODIA iVZW
Obesity, Metabolic Syndrome X
Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity
Obesity is common (>30% of US adults), contributes to substantial morbidity and mortality, but is difficult to treat. Partly this is due to the transient, arduous and modest nature of lifestyle interventions.
- Trial name
- REVIVE (NCT01351753)
- Testing
- Metformin, Orlistat, Topiramate
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Iowa
Pre-diabetes, Lifestyle Risk Reduction
Evidence-based Intervention for Diabetes Prevention
The goal of this behavioral intervention trial is to develop strategies to decrease the incidence of diabetes within the UAE. The investigators will investigate the effectiveness of a group-based telehealth intervention…
- Conditions
- Pre-diabetes, Lifestyle Risk Reduction, Diet Prevention of Metabolic Diseases
- Trial name
- EID (NCT07443995)
- Testing
- Adapted diabetes prevention program, App based support, Patient education materials
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- New York University
Diabetes Mellitus
Prevent/Delay Development of Type 2 Diabetes in Subjects With Impaired Glucose Homeostasis Treated With Acarbose in Primary Care
The purpose of the study is to determine if the administration of small doses of Acarbose can prevent or delay the appearance of Type 2 Diabetes Mellitus in a population of subjects with prediabetes.
- Trial name
- NCT01010100
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- 23 sites in Spain
- Volunteers
- 204 people
- Sponsor
- Bayer
Oral Glucose Tolerance Test, High Fat Tolerance Test
Effects of Fluid Milk in Attenuating Hyperglycemia and Hypertriglyceridemia After Meal
Epidemiological studies indicate that risk of type 2 diabetes is lower when milk is consumed in the regular diet. Milk products are unique in that they produce high insulin response despite their low glycemic index.
- Trial name
- NCT02894112
- Testing
- non-fat milk, carbohydrate control beverage, caloric control beverage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Impaired Glucose Tolerance
Sucralose, Stevia, Gut Microbiome and Glucose Metabolism
This study will determine the influence of two non-caloric sweeteners on glucose metabolism via the gut microbiome in adult men and women.
- Trial name
- NCT02800707
- Testing
- Sucralose, Stevia
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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