Clinical trials: Hyperlipemia
Diabetes Mellitus, Type 1, Hypertension
Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers.
A couple of studies have shown that illuminating the eye with diffuse flickering light is accompanied by an increase of retinal vessel diameters, optic nerve head blood flow and retinal blood flow.
- Conditions
- Diabetes Mellitus, Type 1, Hypertension, Hypercholesterolemia, Regional Blood Flow
- Trial name
- NCT00432029
- Testing
- Forearm blood flow measurement, Flow mediated dilation (FMD), Zeiss Retinal Vessel Analyzer (RVA), Stimulation with Flicker-light
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypercholesterolemia, Hypertriglyceridemia
Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and Hypertriglyceridemia
This study is designed as a pilot study in order to estimate the effect of VAL070-A and VAL070-B products and their variability on LDL cholesterol and lipid metabolism since these data are still unknown for these products and in…
- Trial name
- Lipiback (NCT02989753)
- Testing
- VAL070-A, VAL070-B
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Hyperlipidemia
Bilberry Fruit and Black Rice Derived Anthocyanins on Lipid Status
The primary aim of this study is to directly compare the two major types of anthocyanins found in the diet (cyanidin-type and delphinidin-type) on lipid status in adults.
- Trial name
- NCT03213288
- Testing
- Delphinidin type anthocyanins, Cyanidin type anthocyanins
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Hypercholesterolemia, Flatulence
Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS)
This is a placebo controlled, cross-over, randomized, double blinded study. The intervention food products will be taken as diet prebiotic supplements: 1.
- Conditions
- Hypercholesterolemia, Flatulence, Intestinal Diseases
- Trial name
- FFS (NCT02693782)
- Testing
- Fibre supplement
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Cardiovascular Diseases
Study of the Effectiveness and Safety of Niaspan ® in the Treatment of Lipid Abnormalities in Latin America
Post-Marketing Observational study of Niaspan® tablet in accordance with each country regulations. This study will be conducted in a prospective, single-arm, multi-center format.
- Trial name
- NCT01200160
- Testing
- Niacin
- Where
- 22 sites in Colombia, Mexico and 1 more
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Abbott
Hyperlipidemias, Inflammation
The Effects of Homogenized and Unhomogenized Milk on Postprandial Metabolism in Healthy Overweight Men
The purpose of this study is to compare the effects of homogenized, unhomogenized and skimmed milk on postprandial metabolism in healthy overweight men
- Conditions
- Hyperlipidemias, Inflammation, Atherosclerosis
- Trial name
- NCT01317524
- Testing
- Homogenized milk, Unhomogenized milk, Skimmed Milk
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Dyslipidemia
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
This study will assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD0780 following single and multiple dose administration to healthy subjects with or without elevated Low-Density…
- Trial name
- NCT05384262
- Testing
- AZD0780, Rosuvastatin
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy, Hypercholesterolemia
In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a pivotal enzyme in lipid metabolism and therapeutic target for hypercholesterolemia and atherosclerotic cardiovascular disease (CVD).
- Conditions
- Healthy, Hypercholesterolemia, Hypertension, Overweight
- Trial name
- NCT06675994
- Testing
- PCSK9 Antibody, PCSK9 Enzyme
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Adverse Effects
Method of Fish Oil Administration on Patient Compliance
Many patients complain of fishy breath, upset stomach, or heartburn when taking the recommended amount of fish oil. A common recommendation made by pharmacists is to freeze the fish oil capsules to help decrease adverse…
- Trial name
- NCT01471366
- Testing
- Frozen capsule, Capsule with food, Capsule without food
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Mississippi, Oxford
Hypertension, Hyperlipidemia (E.G., Hypercholesterolemia)
A Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1018-1 and BR1018-2 in Healthy Adult Subjects
The purpose of this study is to evaluate the pharmacokinetic characteristics and compare the safety and tolerability after repeated separate or combined administrations of BR1018-1 and BR1018-2 in healthy adults.
- Trial name
- NCT05460364
- Testing
- BR1018-1, BR1018-2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
HIV, Hypercholesterolaemia
Pharmacokinetic Drug Interaction Study Between Raltegravir and Atorvastatin.
Dyslipidemia is highly prevalent among patients with HIV infection and contributes to the increased cardiovascular disease risk in this patient population.
- Trial name
- AVIATOR (NCT01779687)
- Testing
- raltegravir, Atorvastatin
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cardiovascular Diseases, Type 2 Diabetes Mellitus in Obese
Implementation of a Peer Leader-facilitated Dyadic Intervention
This Pilot Study Large Application builds upon the results of our prior work to 1) Implement and pilot test a peer leader-facilitated 12-week dyadic intervention (Community Health among Asian Indian immigrants (CHAI) Dyad study)…
- Conditions
- Cardiovascular Diseases, Type 2 Diabetes Mellitus in Obese, Hyperlipidemias
- Trial name
- NCT06643806
- Testing
- CHAI dyad study
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Insulin Resistance, Obesity
Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity
A combination of generally regarded as safe (GRAS) compounds named GLY-LOW, which included: alpha lipoic acid, pyridoxamine, nicotinamide, piperine and thiamine, were examined in pre-clinical experiments.
- Conditions
- Insulin Resistance, Obesity, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT06242535
- Testing
- GLY-LOW
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Stress, Blood Sugar; High
Daily Blood Glucose Trends in Patients at Risk for Diabetes
The goal of this study is to learn about the relationship between blood sugar, diet, stress, and metabolic parameters including waist circumference, body mass index (BMI), cholesterol levels and blood pressure in patients at risk…
- Conditions
- Stress, Blood Sugar; High, Cholesterol, Elevated, Diet Habit
- Trial name
- NCT06000735
- Testing
- 7-Day Continuous Glucose Monitoring with Abbott Freestyle Libre 2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Karol E. Watson, MD
Hypercholesterolemia
Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols
The purpose of this study is to investigate the cholesterol lowering effect of a drinkable low fat fermented milk enriched with plant sterol after 3 and 6 weeks of daily consumption in midly hypercholesterolemic people not…
- Trial name
- NCT01340287
- Testing
- 1- plain low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols)., 2- plain low-fat dairy fermented product (drinkable) without plant sterols-esters
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Metabolic Disorders, Abdominal Obesity
Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.
This clinical trial objective is to evaluate the effect of an aerobic physical exercise program on reducing triglycerides, blood pressure, abdominal obesity, altered glucose levels, and the increase in HDL in college-level…
- Conditions
- Metabolic Disorders, Abdominal Obesity, Blood Pressure Disorders, Hypertriglyceridemia
- Trial name
- (EPE_RCTMCS) (NCT06555159)
- Testing
- Physical exercise prescription: Continuous aerobic training (jogging, swimming, static cycling), Control group: Continuous aerobic physical exercise
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Obesity, Hypertriglyceridemia
Effects of Omega-3 Fatty Acids on Markers of Inflammation
The major purpose of this study is to examine the effect of two sources of dietary omega-3 fatty acids, each given at two doses, on potential health benefits related to cardiovascular disease prevention.
- Conditions
- Obesity, Hypertriglyceridemia, Insulin Resistance, Hypertension
- Trial name
- NCT01129050
- Testing
- Fish Oil, Flaxseed Oil
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hyperlipidemias
Determining the Lipid Lowering Effect of Fenugreek Seed Tea
The goal of this randomized clinical trial is to investigate the lipid-lowering effect of fenugreek seed consumed as a tea in patients with hyperlipidaemia, but without diabetes over an 8-week intervention period.
- Trial name
- NCT05858671
- Testing
- Fenugreek Seed Tea, Black Tea
- Where
- 2 sites in United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Obesity, Metabolic Syndrome X
Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons
The purpose of this trial is to study the safety, tolerability and efficacy of an almond enriched hypocaloric diet on weight loss and weight maintenance, as well as on established and emerging cardiovascular risk factors in…
- Conditions
- Obesity, Metabolic Syndrome X, Hyperlipidemia, Hypertension
- Trial name
- NCT00194428
- Testing
- Almond enriched diet, Low fat caloric diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Temple University
Familial Hypercholesterolemia
Return of Actionable Variants Empirical Study
This is a genomic implementation project with ancillary studies to understand the impact on patients' health and well-being of returning genomic results to them and depositing those results in the medical record.
- Trial name
- RAVE (NCT03640234)
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic