Clinical trials: Hyperlipoproteinemia
Diabetes Mellitus, Type 2, Hyperlipidemia
A Brief Intervention to Improve Medication Knowledge and Adherence Among Family Medicine Patients in South Texas
This study examines a brief physician counseling intervention to improved medication knowledge and compliance in family medicine patients who have diabetes, hypertension or high cholesterol.
- Conditions
- Diabetes Mellitus, Type 2, Hyperlipidemia, Hypertension
- Trial name
- NCT00846300
- Testing
- Physician counseling for health behavior change
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hypertension, Hyperlipidemia
A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-231A and AD-231B and AD-231C
To evaluate the pharmacokinetic interactions of AD-231A, AD-231B, and AD-231C in healthy adult volunteers.
- Trial name
- NCT07312773
- Testing
- Treatment A(AD-231A), Treatment B(AD-231B+AD-231C), Treatment C(AD-231A+AD-231B+AD-231C)
- Where
- South Korea
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Hyperlipidemia
A 12 Week, 3-Period Study to Evaluate the Effects of a Dietary Supplement on Lipid Metabolism
This study will evaluate the effects of encapsulated botanical extracts, previously shown to inhibit the enzyme diacylglycerol-acyltransferase-1 (DGAT-1) in vitro, on fasting and postprandial lipid metabolism during an oral fat…
- Trial name
- NCT02366156
- Testing
- Low Dose Grape Blend, High Dose Grape Blend
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Hyperlipidemia
Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study)
To evaluate the primary preventive effect of low-dose pravastatin against coronary heart disease (CHD) in Japanese hypercholesterolemic patients.
- Trial name
- NCT00211705
- Testing
- Diet, Diet+pravastatin
- Volunteers
- 8,000 people
- Sponsor
- Mitsukoshi Health and Welfare Foundation
Oxidative Stress
Study to Evaluate the Effects of XXS on Oxidative Stress in Patients With Mild or Moderate Hyperlipidemia
Given preliminary data in animal (proprietary data) have shown that XXS (a mixture of natural polyphenolic extracts of edible plants) has a significant and favourable effect on oxidative stress notably with a decrease in certain…
- Trial name
- XXS SYMPA (NCT02826083)
- Testing
- XXS, non-XXS
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hyperlipidemia
Regulation of Intestinal and Hepatic Lipoprotein Production by Glucose and Fructose
Increased postprandial plasma triglycerides are associated with increased cardiovascular risk. Chronic consumption of carbohydrates is associated with increased levels of triglycerides.
- Trial name
- glucose (NCT01694446)
- Testing
- Intraduodenal glucose or fructose
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Cardiovascular Diseases, Heart Diseases
Genomic Dissection of a QTL Affecting the Lipid Profile
To search for the genetic cause of the metabolic syndrome, a lipid disorder that poses a major risk for coronary heart disease.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Hyperlipidemia, Familial Combined
- Trial name
- NCT00064688
- Sponsor
- Medical College of Wisconsin
Familial Hypercholesterolemia
Effect of Rapeseed Oil and Sunflower Oil
Familial hypercholesterolemia (FH), an inherited disorder of lipoprotein metabolism, is a risk for early cardiovascular disease (CVD).
- Trial name
- NCT00924274
- Testing
- rapeseed oil, sunflower oil
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus Type 2
Internet Intervention to Improve Rural Diabetes Care
Rural Diabetes Online Care (RDOC) will develop an Internet-based intervention for rural primary care physicians, focusing on improving care for adult patients with diabetes.
- Trial name
- NCT00403091
- Testing
- Internet Intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Chronic Kidney Diease, Diabetes Mellitus
Chronic Kidney Disease and Metabolic Disorders in the Elderly
The goal of this observational study is to investigate the impact of metabolic comorbidities on outcomes in elderly Chinese adults, through two parallel sub-cohorts: one comprising elderly individuals without chronic kidney…
- Conditions
- Chronic Kidney Diease, Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- NCT07494526
- Where
- 2 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Sleep Deprivation
A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation
The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.
- Trial name
- NCT00123214
- Testing
- Controlled Dietary Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Vincent's Medical Center
Familial Hypercholesterolemia
Soy Food Intervention Trial
Familial hypercholesterolemia (FH MIM#143890), an inherited disorder of lipoprotein metabolism, is a risk for early cardiovascular disease (CVD).
- Trial name
- SOYFIT (NCT00924339)
- Testing
- soy protein diet, rapeseed oil
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Hyperlipidemia, Impaired Fasting Glycemia
Effects of Hypolipemic Treatment on Adipokines
The study is planned to show whether monotherapies or combined hypolipemic therapy influence the fasting plasma glucose, serum adipokines (leptin, adiponectin, resistin) and proinflammatory cytokines (interleukin-6, TNF alpha)…
- Trial name
- NCT01099176
- Testing
- To compare monotherapies and combined therapy with each other
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Coronary Artery Disease, Atherosclerotic Plaque
Changes in Plaque Characteristics After Short-term Statin Therapy as Assessed With Coronary CT
INTENSE Trial is a prospective, double-blind, randomized, placebo-controlled, single-center study with two arms (40 mg intensified statin therapy vs matching placebo for rosuvastatin) among statin-naive patients referred to…
- Conditions
- Coronary Artery Disease, Atherosclerotic Plaque, Coronary Computed Tomography Angiography, Statin Therapy
- Trial name
- INTENSE (NCT06603363)
- Testing
- Rosuvastatin 40mg, Coronary Computed Tomography Angiography (Coronary CTA), Blood test
- Where
- Hungary
- Volunteers
- 140 people
- Sponsor
- Prof. Maurovich-Horvat Pál
High Cholesterol/Hyperlipidemia, High Blood Pressure
OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals
The overall objective of this research entity is to reveal the comprehensive health impact of oats in metabolically challenged individuals in a 6-week intervention, compared to that of rice.
- Conditions
- High Cholesterol/Hyperlipidemia, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT05526092
- Testing
- Dietary intervention, Postprandial meal test
- Where
- 2 sites in Finland
- Volunteers
- 72 people
- Sponsor
- University of Turku
HbA1c Level Associated With Lipid Compositions
to Evaluate the Safety and Efficacy of Pitavastatin in Patients With IFG and Hyperlipidemia
Primary Objective : To evaluate that there is no different effect on HbA1c between routine lipid lowering therapy(Livalo 2mg) and intensive lipid lowering therapy(Livalo 4mg) in the hyperlipidemic patients with impaired fasting…
- Trial name
- SIPHON (NCT02056847)
- Testing
- Pitavastatin calcium 4mg, Pitavastatin calcium 2mg
- Where
- South Korea
- Volunteers
- 313 people
- Sponsor
- JW Pharmaceutical
Homozygous Familial Hypercholesterolemia
Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)
Participants with documented homozygous familial hypercholesterolemia (HoFH) who have provided informed consent will receive 2 open-label doses of ARO-ANG3 and be evaluated for safety and efficacy parameters through 36 weeks.
- Trial name
- Gateway (NCT05217667)
- Testing
- ARO-ANG 3 Injection
- Where
- 7 sites in United States, Australia and 2 more
- Volunteers
- 18 people
- Sponsor
- Arrowhead Pharmaceuticals
Healthy, Hyperlipoproteinemia
Lipoprotein Metabolism in Normal Volunteers and Patients With Abnormal Levels of Lipoproteins
Researchers plan to study the fat-rich particles, called lipoproteins, which circulate in the blood. This study is designed to improve understanding of normal, as well as abnormal, lipoprotein metabolism and the role it plays in…
- Trial name
- NCT00001226
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Hyperlipidemia
Japanese Primary Prevention Project With Aspirin
The purpose of this study is to investigate the balance between the risks and benefits of primary prevention by Aspirin in elderly Japanese patients with one or more cerebro/cardiovascular risk factors
- Conditions
- Hypertension, Hyperlipidemia, Diabetes Mellitus
- Trial name
- NCT00225849
- Testing
- Aspirin
- Where
- Japan
- Volunteers
- 10,000 people
- Sponsor
- Ministry of Health, Labour and Welfare, Japan
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