Clinical trials: Hyperlipoproteinemia
Coronary Artery Disease, Diabete Mellitus
Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients
The purpose of this observational study is to understand the impact of polypharmacy on the prognosis of elderly patients with chronic diseases.
- Conditions
- Coronary Artery Disease, Diabete Mellitus, Chronic Kidney Disease, Hypertension
- Trial name
- NCT07180368
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xijing Hospital
Cardiovascular Disease, Hypertension
Cardiovascular Intervention Improvement Telemedicine Study
Cardiovascular disease (CVD) is the leading cause of death in the United States; more than 80% of veterans have > 2 risk factors for CVD.
- Conditions
- Cardiovascular Disease, Hypertension, Diabetes, Hyperlipidemia
- Trial name
- NCT01142908
- Testing
- Pharmacist CVD
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- VA Office of Research and Development
Hyperlipoproteinemia (a)
Study of YKYY032 Injection in Adults With Hyperlipoproteinemia (a)
Phase II clinical trial to evaluate the efficacy and safety of YKYY032 injection in adults with hyperlipoproteinemia (a)
- Trial name
- NCT07914660
- Testing
- YKYY032 group
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd.
Hyperhomocysteinemia, Hyperlipoproteinemias
Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms.
This randomized, double-blind, placebo-controlled trial will evaluate the impact of methylfolate, pyridoxal-5'-phosphate (P5P), and methylcobalamin supplementation on homocysteine and LDL-C levels in individuals with low to…
- Trial name
- VITAGEN-H (NCT06163443)
- Testing
- Vitamin B
- Where
- Russia
- Volunteers
- 54 people
- Sponsor
- S.LAB (SOLOWAYS)
Diabetes Mellitus, Type 2, Hypertension
Improving Medication Adherence in Comorbid Conditions
This study is designed to study how adults with Type 2 Diabetes and either high blood pressure and/or high blood cholesterol manage their treatment regimen. It is also called the Diabetes Management Study.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemia
- Trial name
- NCT00072891
- Testing
- telephone counseling
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Primary Hypercholesterolemia, Mixed Hyperlipidemia
Lipid Efficacy Study (0524B-022)(COMPLETED)
This is a 12-week clinical trial in patients with primary hypercholesterolemia or mixed hyperlipidemia, studying the effects of coadministered MK0524B on lipids. There will be 6 scheduled clinic visits, and 7 treatment arms.
- Trial name
- NCT00269217
- Testing
- niacin (+) laropiprant (+) simvastatin, Comparator: niacin (+) laropiprant, Comparator: simvastatin
- Volunteers
- 1,400 people
- Sponsor
- Merck Sharp & Dohme LLC
Familial Hypercholesterolemia
Atorvastatin Three Year Pediatric Study
The purpose of this study is to characterize three year descriptive growth and development (ie, height, weight, body mass index, Tanner Stage) and efficacy of cholesterol reduction in pediatric subjects with Heterozygous Familial…
- Trial name
- NCT00827606
- Testing
- atorvastatin
- Where
- 40 sites in United States, Belgium and 13 more
- Volunteers
- 272 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Primary Hypercholesterolemia or Mixed Hyperlipidemia
QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated Low Density Lipoprotein Cholesterol (LDL-C)
To evaluate the efficacy, safety and immunogenicity of QCL7401 subcutaneous administration in patients with primary hypercholesterolemia or mixed hyperlipidemia with poorly controlled LDL-C elevated on optimized lipid-lowering…
- Trial name
- NCT07441317
- Testing
- QLC7401
- Volunteers
- 780 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Cardiovascular Diseases, Coronary Disease
Genetic Epidemiology of Hypertriglyceridemia
To determine prospectively the role of elevated plasma triglyceride (TG) as a risk factor for 20-year coronary heart disease (CHD) mortality in familial combined hyperlipidemia (FCHL) and familial hypertriglyceridemia (FHTG), the…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Hyperlipidemia, Familial Combined, Hyperlipoproteinemia Type iv
- Trial name
- NCT00005368
- Sponsor
- University of Washington
Hypercholesterolemia and Mixed Hyperlipidemia
A Study to Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
The purpose of this study is to compare the effectiveness, safety of SYH2053 in Participants with primary hypercholesterolemia or mixed dyslipidemia. A total of 156 Participants were actually enrolled
- Trial name
- NCT07421232
- Testing
- Inclisiran (Leqvio®) 300mg
- Where
- China
- Volunteers
- 156 people
- Sponsor
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Sleep Deprivation
A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation
The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.
- Trial name
- NCT00123214
- Testing
- Controlled Dietary Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Vincent's Medical Center
Homozygous Familial Hypercholesterolemia
A Study to Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH
AK102 is being developed for the treatment of HoFH. The study will be conducted in 2 parts, part 1 is open label, single arm study to evaluate the safety, tolerability and efficacy of PCSK9 inhibitor AK102, and part 2 is double…
- Trial name
- NCT03933293
- Testing
- AK102, Statins, Ezetimibe
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- Akeso
Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events
Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk
The primary objective of the study was to evaluate the effect of 12 weeks of subcutaneous evolocumab administered every 2 weeks and once a month, compared with placebo, on percent change from baseline in LDL-C when used in…
- Trial name
- AMG145 (NCT01953328)
- Testing
- Atorvastatin, Evolocumab
- Where
- 54 sites in Japan
- Volunteers
- 409 people
- Sponsor
- Amgen
NASH - Nonalcoholic Steatohepatitis
A Study of ALG-055009 in Healthy Volunteers and Subjects With Hyperlipidemia
A Randomized Study of ALG-055009 Drug to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses in Healthy Volunteers and Subjects with Hyperlipidemia
- Trial name
- NCT05090111
- Testing
- ALG-055009
- Where
- France
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Aligos Therapeutics
Hepatitis B, Chronic
A Clinical Research on Disease Progression and Intervention of Chronic HepatitisB
HBV(hepatitis B virus) with metabolic comorbidities may accelerate liver disease progression and increase the risk of HCC(Hepatocellular Carcinoma)development.
- Trial name
- NCT05057065
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Hong Ren
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Quebec
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-QC (NCT02789800)
- Testing
- DIMAC02
- Where
- 2 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Université de Sherbrooke
Dyslipidemia, Hypercholesterolemia
Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia
The purpose of this study is to determine the safety and efficacy of different doses of CAT-2003 in patients with hyperlipidemia when CAT-2003 is taken for 4 weeks.
- Conditions
- Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia
- Trial name
- PATHWAYS I (NCT01912560)
- Testing
- CAT-2003, Statin
- Where
- 14 sites in United States, Canada
- Volunteers
- 99 people
- Sponsor
- Catabasis Pharmaceuticals
Hypertension, Cardiovascular Disease
Regional Innovation in Chronic Disease and Elderly Care
This project aims to develop a community-based health promotion intervention model for populations at potential risk of metabolic syndrome.
- Conditions
- Hypertension, Cardiovascular Disease, Hyperlipidemia, Hyperglycemia
- Trial name
- NCT07578090
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Fu Jen Catholic University
Hyperlipidemia
Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemia
Evaluation of the efficacy and safety of multiple subcutaneous injections of SHR-1918 in patients with hyperlipidemia in poor control: a multicenter, randomized, double-blind, placebo-controlled phase II clinical trials
- Trial name
- NCT06471218
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Type2 Diabetes, Self Efficacy
The Effect of Tele-Nursing Based Motivational Interviewing in Individuals With Type 2 Diabetes:RCT
This study carried out to examine the effect of tele-nursing based motivational interviewing on diabetes self-efficacy, diabetes self-management and metabolic control parameters (Body mass index, waist circumference…
- Conditions
- Type2 Diabetes, Self Efficacy, Self Management, Tele-nursing
- Trial name
- NCT05628259
- Testing
- Tele-Nursing based Motivational Interviewing
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Pamukkale University
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