Clinical trials: Hyperphagia
Binge Eating, Inhibition, Psychological
Transcranial Magnetic Stimulation and Inhibitory Control Training to Reduce Binge Eating: Brain and Behavioral Changes
People with BE are characterized by high impulsivity, high levels of craving for high-calorie foods, deficits in inhibitory control, and maladaptive decision making.
- Trial name
- BE-NEMOIC (NCT06649994)
- Testing
- Active iTBS of the DLPFC, Active iTBS of the vmPFC, Computerized inhibitory control training
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Raquel Vilar López
Prematurity, Neonatal Screening
Amino Acid and Acylcarnitine Profiles in Premature Neonates
Primary Hypotheses of the study include: Metabolic profiles are influenced by gestational age, chronological age, type and degree of nutritional support and illness Metabolic profiles differ between neonates who receive…
- Conditions
- Prematurity, Neonatal Screening, Parenteral Nutrition
- Trial name
- NCT00865150
- Where
- 2 sites in United States
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Prader-Willi Syndrome, Obesity
Understanding the Role of Gut Microbiota in Hyperphagia in Prader-Willi Syndrome
This study aims to use a high-fiber supplementation, an intervention known to create shifts in the gut microbiota towards a healthier structure, to explore the relationship between gut microbiota, appetite control and feeding…
- Trial name
- PWSGUT (NCT05541003)
- Testing
- NBT-NM108
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obesity
Biology and Experience of Eating in Women With Obesity
The purpose of this study is to understand how the opioid system is involved in eating behavior.
- Trial name
- BEE (NCT02805972)
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sleep Disorder, Hyperphagia
Effect of Deep Propioceptive Stimulation in Prader-Willi Syndrome
The main objective is to study the effect of deep propioceptive stimulation with a heavy blanket for 2 weeks compared with a placebo blanket on sleep quality and behavior in patients with PWS
- Conditions
- Sleep Disorder, Hyperphagia, Behavior Disorders
- Trial name
- NCT05044000
- Testing
- Deep propioceptive stimulation
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Obesity, Overweight
Preventing Obesity in Military Communities-Adolescents
To determine whether reducing loss of control eating (LOC) with Interpersonal Psychotherapy-Weight Gain (IPT-WG) will be effective for adolescent military-dependents who report such behavior.
- Conditions
- Obesity, Overweight, Binge Eating
- Trial name
- POMC-A (NCT02671292)
- Testing
- Interpersonal Psychotherapy, Health Education
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Binge-Eating Disorder, Circadian Rhythm Disorders
The Role of the Circadian System in Binge Eating Disorder
Binge eating disorder (BED) shows prominent circadian features that suggest a delay in circadian phase, and preliminary evidence shows binge eating may be responsive to chronobiological interventions, implicating a circadian…
- Trial name
- CHRONO-BE (NCT04724668)
- Testing
- Melatonin (3hrs before DLMO), Morning light version 1, Morning light version 2
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Obesity, Binge Eating
Treatment of Binge Eating in Obese Patients in Primary Care
This study will test the effectiveness of two empirically-supported but distinct treatments for recurrent binge eating in obese patients: 1) Cognitive Behavior Therapy, using a pure self-help approach and 2) sibutramine, an…
- Trial name
- NCT00537810
- Testing
- Sibutramine, Self-help CBT + Sibutramine
- Where
- 3 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
Impact of Exercise on the Metabolic Consequences of Overeating
The primary purpose of this study is to examine the effects of 1-week of overeating on important clinical metabolic health outcomes (e.g., glucose tolerance, blood lipid profile, and blood pressure) and factors regulating the…
- Trial name
- XO (NCT02701738)
- Testing
- Overeating Protocol
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity
Individual Differences in Children's Susceptibility to Overeating
The portion size of foods has been identified as an important determinant of energy intake in children. It remains to be determined to what extent child weight status and the relative reinforcing value of food may interact with…
- Trial name
- NCT01905293
- Testing
- Feeding Study
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hyperalimentation and Obesity
Cognitive Processes Study in Obese Women With and Without Eating Disorders
The P300 is one of the cognitive wave of the Event-Related Potential (ERP) that is used to investigate the cognitive process. The P300 component are accepted as electro-physiological markers of neuropsychiatric disorders like…
- Trial name
- P300 (NCT01948414)
- Testing
- electroencephalography, Blood sampling, Questionnaires regarding eating habits (TFEQ, EDI) and anxiety/depression (HAD)
- Where
- France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Eating Disorder
Impact of an Oral Health Intervention
This pilot study will assess the effectiveness of an original oral health education program on affecting the behaviors of patients diagnosed with eating disorders.
- Trial name
- NCT03921632
- Testing
- Smiles Matter Oral Health Education Series
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infections, Total Parenteral Nutrition
Immune Modulation by Parenteral Lipids
Immune modulating properties of parenteral lipid emulsions seem to contribute to the increased risk for infections which remains associated with the use of total parenteral nutrition.
- Trial name
- NCT00734916
- Testing
- Parenteral lipid emulsion (Omegaven), Parenteral lipid emulsion (Intralipid), Parental lipid emulsion (Saline 0.9%)
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Prader-Willi Syndrome
PWS European Blood Bank for Infants and Controls From 0 to 48 Months
The present project aims to determine the underlying mechanisms for the switch from failure to thrive to excessive weight gain and hyperphagia with impaired satiety in PWS.
- Trial name
- NCT02529085
- Testing
- blood samples
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Binge Eating
EMOTE: a Smartphone Application for Binge Eating Based on DBT Skills
Binge eating, whether formally diagnosed or occurring at subthreshold levels, is associated with adverse health consequences and decreased quality of life.
- Trial name
- NCT06683456
- Testing
- eMOTE
- Where
- Portugal
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Binge-Eating Disorder
EXOMIND (BTL-995) for Reduction of Binge-eating
The goal of this clinical trial is to evaluate if the treatment with the BTL-995-rTMS device is able to reduce binge eating in adults above the age of 22 years.
- Trial name
- NCT06910592
- Testing
- Treatment with BTL-995-rTMS
- Where
- Bulgaria
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Pregnancy, Binge Eating
Empowering Mindfulness, Body Respect, and Compassionate Eating Among Women Who Binge Eat During Pregnancy
Primary Study Aims: 1. To evaluate the feasibility, acceptability, and preliminary efficacy of a 10-week mindful eating self-help program for women who binge eat during pregnancy.
- Trial name
- NCT05581095
- Testing
- Mindful Eating Self-Help Program, Mindful Eating Smartphone Application (Am I Hungry? Virtual Coach)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Charlotte
Bulimia Nervosa
Self-Control in Bulimia Nervosa
This study examines the influence of acute fasting and eating on self-control in adult females with and without bulimia nervosa (BN).
- Trial name
- NCT04409457
- Testing
- fasting state, fed state, magnetic resonance imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Binge Eating Disorder, Cognitive Therapy/Methods
The Psychological Treatment of Overweight Binge Eaters Minority Supplement
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on…
- Conditions
- Binge Eating Disorder, Cognitive Therapy/Methods, Mental Disorders/Epidemiology, Obesity/Epidemiology
- Trial name
- NCT01208259
- Testing
- Cognitive Behavioral Therapy (CBT), Interpersonal Therapy (IPT)
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Bloodstream Infections, Short Bowel Syndrome
Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants
The purpose of this research study is to evaluate the effects (good and bad) of supplementation with Glutamine to that of a placebo (L-alanine), on your child and their Short Bowel Syndrome.
- Conditions
- Bloodstream Infections, Short Bowel Syndrome, Development, Nutrition
- Trial name
- NCT01576003
- Testing
- Glutamine, L-alanine
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati