Clinical trials: Hypersensitivity Dentin
Hypersensitivity Dentin, Dental Restoration Failure of Marginal Integrity
Clinical Evaluation of Short Dentin Etching
To evaluate and compare the two-year clinical performance of Class I resin composite restorations utilizing a universal adhesive used in different etch-and-rinse strategies (15-second and 5-second etching) and self-etch…
- Trial name
- NCT06772051
- Testing
- Resin composite restoration bonded using universal adhesive in etch and rinse mode (15 seconds etching), Resin composite restoration bonded using universal adhesive in etch and rinse mode (5 seconds etching), Resin composite restoration bonded using universal adhesive in self-etch mode
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dentin Hypersensitivity, Non-carious Cervical Lesions, Gingival Recession Localized Moderate
Polymeric Nano Calcium Fluoride Varnish, Diode Laser, and Their Combination for Dentin Hypersensitivity
The aim of the study is to assess the effect of polymeric nano calcium fluoride Varnish (Oli-NANO seal), 976 nm diode laser solely and combination of both therapies in the treatment of dentin hypersensitivity
- Trial name
- NCT07418788
- Testing
- Olinano seal, Diode Laser, Olinano seal and Diode Laser
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Tooth Discoloration, Tooth Sensitivity
Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching Gel
The goal of this clinical trial is to learn the effect of Nano-fortified Bleaching on whitening and sensitivity of teeth.The main questions it aims to answer are: Does Nano-fortified Bleaching gel is more effective in enhancing…
- Trial name
- NCT06904118
- Testing
- Nano-reinforced Novel Hydrogen peroxide gel, Conventional Hydrogen peroxide gel without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dentin Hypersensitivity
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only…
- Trial name
- NCT07215767
- Testing
- Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice
- Where
- 3 sites in United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentine Hypersensitivity
Study to Investigate the Effect of Changes in Dentinal Hypersensitivity on Oral Health Parameters
This exploratory study will investigate the effect of long-term management of Dentine Hypersensitivity (DH) by use of a sensitivity toothpaste on selected oral health parameters, such as changes in oral hygiene (as measured by…
- Trial name
- NCT07768969
- Testing
- Test Toothpaste
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
Effect of Chemical and Light Bleaching Techniques on Color Change, Dentin Hypersensitivity and Patient Satisfaction
Aim of The Study This study aims is to evaluate color change, dentin hypersensitivity and patient satisfaction after different bleaching techniques at different time intervals.
- Trial name
- NCT07669324
- Testing
- Light activated bleaching, Chemically activated bleaching
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nahda University
Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG
Desensitizing Effect and Tooth Color Change After Using Giomer-based Varnish Versus Bioactive Glass Air Polishing in Treating Cervical Hypersensitive Lesions
This trial is test the dentin hypersenstivity using Giomer based Varnish versus Bioactive glass air polishing system in patients with non-cervical lesions.
- Trial name
- NCT05981625
- Testing
- Giomer varnish containing surface pre-reacted glass fillers
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Dentin Hypersensitivity
A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Toothpastes
The aim of this exploratory clinical study is to investigate the tooth whitening potential, Dentin Hypersensitivity (DH) efficacy, and oral tolerability of two experimental toothpastes in a DH population with appropriate tooth…
- Trial name
- NCT07297732
- Testing
- Test Toothpaste 1, Test Toothpaste 2, Reference Toothpaste
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- HALEON
Periodontal Diseases, Hypersensitivity Dentin
Clinical Efficacy of Vector Paro With Hydroxyapatite in the Supportive Therapy of Periodontitis
Enamel is the most calcified tissue in the body and is composed of 92-96% by organic substances in particular hydroxyapatite. Hydroxyapatite nanoparticles are similar to the morphology and structure of tooth enamel apatite…
- Conditions
- Periodontal Diseases, Hypersensitivity Dentin, Hydroxyapatite
- Trial name
- PAROXY (NCT07482280)
- Testing
- hydroxyapatite debridment, ultrasonic debridment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Dentin Hypersensitivity
Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste
Assess the clinical efficacy of 5% Potassium Nitrate Toothpaste (Colgate-Palmolive Company, New York, NY, USA) on providing dentinal hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection…
- Trial name
- NCT06956599
- Testing
- test toothpaste, Control toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Sensitivity, Tooth
Dentinal Hypersensitivity Reduction Efficacy Study
Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
- Trial name
- NCT06960148
- Testing
- CSPR Toothpaste, Colgate Dental Cream Toothpaste
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentinal Hypersensitivity
Dentinal Hypersensitivity Reduction
The objective of this clinical study is to assess the efficacy of a dentifrice containing stannous fluoride (Colgate-Palmolive Company, New York, NY, USA) as compared to a commercially-available potassium-based toothpaste…
- Trial name
- NCT06244290
- Testing
- Colgate SNF, Sensodyne Extra Whitening, Colgate Fluoride (CDC)
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Hypersensitivity, Quality of Life
Validation of a French Version of the DHEQ
Dentin hypersensitivity (DH) results in brief, sharp pain in response to a stimulus. It often seems to be underdiagnosed but also undertreated due to the lack of consensus on the topic.
- Trial name
- DHEQ-VALID (NCT06466200)
- Testing
- Schiff Test, GOHAI questionnaire, OHIP questionnaire
- Where
- 3 sites in France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Dentin Desensitizing Agents, Dentin Hypersensitivity, Non-carious Cervical Lesions
Clinical Efficacy of Using Bioactive Desensitizer Gel
To evaluate and compare the clinical effectiveness of a Bioactive Desensitizer Gel (which releases calcium and phosphate to form hydroxyapatite) versus a standard 5% Sodium Fluoride (NaF) Varnish in reducing cervical dentin…
- Conditions
- Dentin Desensitizing Agents, Dentin Hypersensitivity, Non-carious Cervical Lesions, Dentin Hypersensitivity
- Trial name
- NCT07323693
- Testing
- Treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Sensitivity
The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.
The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent…
- Trial name
- NCT07173296
- Testing
- Opalescence XTra Boost 40% HP, Pola Office Plus 37.5% HP
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dentin Hypersensitivity
Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration, Dentin Bonding, and Clinical Durability of Composite Restorations.
This study will investigate the efficacy of three diode laser wavelengths 445 nm, 660 nm, 970 nm when applied just before placement of composite restoration on reducing postoperative sensitivity from Non-carious cervical lesions…
- Trial name
- NCT05501691
- Testing
- 445 nm Diode Laser Wavelength, 660 nm Diode Laser Wavelength, 970 nm Diode Laser Wavelength
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity
Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions
84 patients who fulfill the inclusion criteria will be enrolled to the study. For every patient a tooth of complain which fulfill the inclusion criteria will be selected, so the total number of included teeth will be 84 teeth.
- Conditions
- Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity, Dentin Desensitizing Agents, Desensitization
- Trial name
- NCT07113847
- Testing
- Resin-Based Desensitizer, Laser Desensitizer, Fluoride-Based Desensitizer
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Dentin Hypersensitivity
Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivity (A 6m Randomized Clinical Trial)
The aim of the study to compare the clinical effectiveness of Episodic use of Bioactive Silica Based versus continuous use of fluoride based desensitizing toothpastes in management of dentin hypersensitivity (DH) of adult…
- Trial name
- NCT07120139
- Testing
- episodic use of the desensitizing toothpaste, continuous use of the conventional desensitizing toothpaste
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz