Clinical trials: Hypersensitivity Dentin
Inflammation, Pulpitis
Assessing of Tooth Sensitivity Using Ibuprofen Before in Office-tooth Bleaching
Ibuprofen has been recognized as anti-inflammatory and analgesic. The purpose of this study is to determine the effect of ibuprofen 400 mg on tooth sensitivity (TS) caused by in-office bleaching.
- Trial name
- NCT01530217
- Testing
- Ibuprofen.
- Volunteers
- 30 people
- Sponsor
- Universidade Estadual de Ponta Grossa
Dentin Sensitivity
To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)
This single centre study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a standard fluoride…
- Trial name
- NCT02923895
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
A Comparison of Long-Term Effectiveness of Two Desensitizing Products
This randomized, controlled, clinical trial aimed to compare the 6- month clinical performance of a desensitizer that contains calcium phosphate TM with a two-step self-etch adhesive SE and placebo (distilled water).
- Trial name
- NCT03851900
- Testing
- Teethmate Desensitizer (TM), Clearfil SE Bond 2, Distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Dentin Sensitivity
A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population
The purpose of this study is to evaluate the efficacy of the 0.454 percentage (%) weight/weight (w/w) stannous fluoride (SnF2) toothpastes for the relief of dentine hypersensitivity (DH) in China.
- Trial name
- NCT05750745
- Testing
- Sensodyne Sensitivity & Gum, Crest Cavity Protection Fresh Lime, Sensodyne Repair and Protect
- Where
- China
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- HALEON
Caries,Dental, Sensitivity, Tooth
Post-operative Sensitivity in Resin Composites
This triple-blind, randomized clinical trial was conducted at the department of Operative dentistry. A total of 60 participants were recruited and were randomly distributed into two groups A and B.
- Trial name
- NCT06242184
- Testing
- Group A(Nano-fortified Adhesive), Group B(Adhesive without nanoparticles)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Fluorosis, Dental, Non-Fluoride Enamel Opacities
Treatment of Hypersensitivity Using Diode Laser and Desensitising Agent on Fluorosed and Non-fluorosed Teeth
The present study was designed as a randomised controlled clinical trial which was unicenter, double-blinded, parallel designed study, according to the Consolidated Standards of Reporting Trials (CONSORT) criteria, 2010.
- Conditions
- Fluorosis, Dental, Non-Fluoride Enamel Opacities, Dentin Sensitivity
- Trial name
- NCT03237793
- Testing
- Fluorosed Group, Non Flourosed Group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Tooth Demineralization, Tooth Sensitivity
Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study
This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by…
- Conditions
- Tooth Demineralization, Tooth Sensitivity, Enamel Mineralization Disorders, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07329244
- Testing
- Graphene-reinforced CAD/CAM polymer (G-CAM®)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Dentine Hypersensitivity
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls.
- Trial name
- NCT01827670
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity, Oral Hygiene
A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
The main aim of this study is to investigate the ability of an experimental dentifrice containing 5 percent (%) potassium nitrate (KNO3), 1% alumina and 5% sodium tripolyphosphate (STP), to maintain tooth color and reduce…
- Trial name
- NCT06150573
- Testing
- Test Dentifrice, Reference Dentifrice (Aquafresh Cavity Protection)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Hypersensitivity
the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity
to solve the problem of hypersensitivity, I will use two different materials ( Giomer versus Sodium Fluoride) and compare between their effects in reliving the symptoms
- Trial name
- NCT03818945
- Testing
- shofu PRG barrier coat, Sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Sensitivity
Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity
The goal of this clinical trial will be to evaluate the effect applying an experimental gel based on cannabidiol oil (CBD) on tooth sensitivity induced by tooth bleaching with 35% hydrogen peroxide (HP).
- Trial name
- NCT07027566
- Testing
- Potassium nitrate and sodium fluoride, Cannabidiol (CBD) Gel, Natrosol 4% Gel
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity
The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial
The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal…
- Trial name
- S-PRG (NCT06276777)
- Testing
- Tooth varnish (PRG Barrier Coat from Shofu), Tooth varnish (Clinpro white varnish 3M)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eman Omar Elfarouk
Dentin Sensitivity
Tooth Sensitivity Relief by Two Mouthrinses
This study is for people with sensitive teeth and involves going to the dentist for 6 visits over 8 weeks. During the first 2 weeks, everyone will just brush their teeth two times a day with the fluoride toothpaste provided.
- Trial name
- NCT01133379
- Testing
- 12027-019, 12027-020, 12027-021
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Dentin Sensitivity
A Clinical Study Assessing the Effects of a Marketed Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching
The aim of this study is to investigate the efficacy of a marketed dentifrice containing 5 percent (%) NovaMin (Calcium Sodium Phosphosilicate) to reduce tooth sensitivity during and post tooth bleaching compared to a marketed…
- Trial name
- NCT06608368
- Testing
- Test Dentifrice (Sensodyne Repair and Protect Original Mint), Positive Control Dentifrice (Sensodyne Fresh Mint), Reference Dentifrice (Crest Cavity Protection Regular)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity
The aim of this study is to investigate the longitudinal efficacy of a potassium nitrate mouthwash formulation when used as an adjunct to brushing with a standard fluoride dentifrice for the relief of dentinal hypersensitivity…
- Trial name
- NCT02226562
- Testing
- Potassium nitrate and sodium fluoride, Standard fluoride dentifrice
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
Desensitizing Efficacy of Polymeric Nano Calcium Fluoride Containing Varnish
The aim of this study is to evaluate the Desensitizing efficacy of polymeric nano calcium fluoride containing varnish and its implementation into clinical practice.
- Trial name
- NCT04614727
- Testing
- polymeric nano calcium fluoride containing varnish NANO SEAL
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samar Saad
Dentin Sensitivity
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex…
- Trial name
- NCT02919202
- Testing
- Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride., Self-etching Dentine Bonding Agent
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Kent
Dentin Sensitivity
Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity
This will be a single centre, two week, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), controlled study, in participant…
- Trial name
- NCT02773758
- Testing
- Stannous Fluoride Dentifrice, Sodium monofluorophosphate Dentifrice
- Where
- Canada
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity, Erosive Tooth Wear
Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.
The goal of this observational study is to learn about tooth wear and tooth sensistivity and reasons for these conditions in five locations throughout the United States.
- Trial name
- NCT07195357
- Testing
- epidemiological
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Indiana University
Gingival Recession, Generalized, Gingival Recession Generalized Moderate
Using Calcium Hydroxylapatite To Treat Gum Recession and Tooth Hypersensitivity
Study Purpose and Objectives: This study will utilize calcium hydroxylapatite (CaHA) to treat recession and hypersensitivity of the gums. The objectives of the study are: 1.
- Conditions
- Gingival Recession, Generalized, Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate, Tooth Sensitivity
- Trial name
- NCT06826391
- Testing
- Calcium hydroxylapatite
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- American Academy of Facial Esthetics