Clinical trials: Hypersensitivity Reaction
Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia
Diphenhydramine and Sweating
In 2012, it was estimated that nearly 1 in 4 Canadians suffer from allergic rhinitis. To add, 78% of individuals working in predisposing environments are predicted to develop occupational rhinitis.
- Conditions
- Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia, Allergic Rhinitis, Sweating
- Trial name
- BENEXE2022 (NCT05586477)
- Testing
- Diphenhydramine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Severe Asthma
Effect of Biologicals on Alternative Functions of Eosinophils in Severe Asthma
The investigators will measure different cytokines in the sputum (interleukin ((IL))-3, granulocyte-macrophage colony-stimulating factor ((GM-CSF)), IL5, IL-13, IL-33, IL-4, IL-25 thymic stromal lymphopoietin ((TSLP)) and…
- Trial name
- NCT04520165
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Liege
Parent-Child Relations
Promoting Socioemotional Development in Early Childhood: Implementation and Evaluation of the VIPP-SD Parenting Intervention in Portugal
The Video-feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) is an attachment-based intervention aimed at promoting parental sensitivity and the use of developmentally appropriate, non-coercive…
- Trial name
- SAF-Parents (NCT07153198)
- Testing
- VIPP-SD
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Allergy, Anxiety
The Effects of Virtual Reality and Music on Pain, Anxiety, Itching, and Vital Signs
Aim: This study aimed to examine the effects of virtual reality and music on pain, anxiety, itching, and vital signs of children during a skin prick test and evaluation.
- Conditions
- Allergy, Anxiety, Pain, Itching
- Trial name
- NCT06479967
- Testing
- The VR glasses group, the music group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uludag University
Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,
Evaluation of a Regional Electronic Health Information Exchange's Clinical Health Record
The Shared Health CHR™ (Clinical Health Record) offers point-of-care clinical reporting and decision support based primarily on patient claims data aggregated across various health care settings, and is one example of the types…
- Conditions
- Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,, Gastroenteritis, Seizures, and Bacterial Pneumonia)
- Trial name
- NCT00978744
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma
A Comparative Study to Investigate the Difference in Blood Levels of Two Different Formulations of GSK5784283
The purpose of this study is to compare how two different formulations of the study medicine (GSK5784283) move through the body over time (pharmacokinetic [PK] study) in healthy adults.
- Trial name
- NCT07712393
- Testing
- GSK5784283
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Consent Forms, Asthma
Informed Consent Formats by Information Preference and Priority
This study will test whether different formats of medical informed consent documents can help improve understanding and confidence in decision-making for clinical trials. The study will be primarily run through an online survey.
- Trial name
- NCT03416907
- Testing
- Original consent form, Shortened consent form, Reordered, shortened consent form
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Asthma
Bronchoscopy With Bronchial Biopsies Sub-study of: Persistence of Airway Inflammation and Remodeling in Asthma Remission
This study aims at determining the patterns of asthma remission, the prevalence of these different patterns and the various factors associated with such remissions and possible recurrences of asthma, in order to determine the…
- Trial name
- NCT00526344
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma; Allergic Rhinitis
Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers
A randomized, single-center, double-blind, ascending multiple-dose, placebo-controlled study to evaluate the tolerability and pharmacokinetics of CSPCHA115 capsules in Chinese healthy volunteers.
- Trial name
- NCT04161547
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Eczema, Asthma
Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-up to 5 Years
The investigators had conducted a double-blind, randomized placebo-controlled clinical trial studying the effects of 6 months probiotics supplementation from birth on allergic disease and sensitization up to 2 years of age.
- Conditions
- Eczema, Asthma, Allergic Rhinitis
- Trial name
- NCT00365469
- Testing
- Probiotic
- Where
- Singapore
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Asthma
ROTAHALER Device Optimization Study
This study will compare the pharmacokinetic (PK) of Fluticasone Propionate/Salmeterol combination (FSC) 100/50 micrograms (mcg) delivered via the capsule-based inhaler (Rdpi) relative to FSC 100/50 mcg delivered via the…
- Trial name
- NCT01890863
- Testing
- Fluticasone Propionate / Salmeterol Xinafoate DISKUS, Fluticasone Propionate / Salmeterol Xinafoate ROTACAP
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Atopy, Allergy
Biodiversity Intervention and Atopic Sensitization
Children will receive biodiversity intervention or placebo. The proof of concept trial is double blind. Intervention will start at the age of 2 months and last 10 months. Children will be randomized to arms.
- Conditions
- Atopy, Allergy, Allergic Rhinitis, Allergic Sensitisation
- Trial name
- PREVALL (NCT03872219)
- Testing
- Nature-based materials
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Allergies
Does Omega-3 Fatty Acid Supplementation in Pregnancy and During Lactation Protect the Child From Allergic Disease?
The incidence of allergic diseases has increased and a relation between allergy and dietary fatty acids has been proposed. Modulation of the maternal immune function during pregnancy may have an impact on future clinical outcomes…
- Trial name
- NCT00892684
- Testing
- Omega-3 long chain polyunsaturated fatty acids
- Where
- Sweden
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Asthma
To Evaluate Newly Developed Pictogram Cards and Their Utility in Improving Inhaler Techniques in Asthmatic Patients
To evaluate newly developed pictogram cards and their utility in improving inhaler techniques in asthmatic patients.
- Trial name
- NCT06562764
- Testing
- Counselling by the Trained Pharmacist, Pictograms Cards and Counselling by the Trained Pharmacist
- Where
- Pakistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Asthma
An Observational Study to Investigate How Patients Experience the Ability to Adjust Their Asthma Maintenance Medication
An observational study to investigate how patients experience the ability to adjust their asthma maintenance medication according to instructions received from their physician.
- Trial name
- INVOLVE (NCT00577265)
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Allergic Fungal Rhinosinusitis
Sinonasal Risk Factors for Occurrence of Unilateral Versus Bilateral Allergic Fungal Rhinosinusitis .
This study aims to assess Sinonasal risk factors for occurrence of unilateral versus bilateral allergic fungal rhino sinusitis regarding:: 1. anatomical variations and correlate radiological finding with intraoperative finding.
- Trial name
- NCT06376071
- Testing
- functional endoscopic sinus surgery
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rhinitis, Asthma
Airway Inflammation and Bronchial Hyperresponsiveness in Rhinitic Children With or Without Asthma
This is a prospective observational study , to clarity the characteristics of airway inflammation, airway reactivity and airway resistance in rhinitic children with or without asthma and to explore the possible predictors in the…
- Conditions
- Rhinitis, Asthma, Inflammation, Hypersensitivity
- Trial name
- NCT02360072
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Healthy, Allergy
Normal Values of Facial Thermography
An objective of this study is to standardize temperature values derived from thermograms of the facial region. It is anticipated that the mean temperature of a defined region of interest, such as the eyes, nose, or sinuses, might…
- Conditions
- Healthy, Allergy, Allergic Rhinoconjunctivitis
- Trial name
- NCT00411606
- Testing
- Thermography
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- West Penn Allegheny Health System
Food Allergy
Basophile Activation Testing (BAT) in Hazelnut Allergy (Hazelnut BAT Study)
The proposed study intends to compare the outcome of food challenge in hazelnut allergic patients with the outcome of basophile activation tests using hazelnut extract and components.
- Trial name
- NCT03079206
- Testing
- Food challenge, skin testing, blood sampling
- Where
- Switzerland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Asthma
Title: Comparative Effectiveness of Asthma Interventions Within an AHRQ PBRN
The overall goal is to identify best practices for improving health outcomes for patients with asthma using comparative effectiveness research within an Agency for Healthcare Research and Quality (AHRQ) Practice-Based Research…
- Trial name
- NCT01280500
- Testing
- electronic medical record, Integrated Approach to Care, usual care
- Where
- 2 sites in United States
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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