Clinical trials: Hyperspectral Imaging
Wounds
Outcome Assessment in Patients Treated With Hyperbaric Oxygen Using OxyVu Tissue Oxygenation Monitoring System
The objective is to define patient eligibility for hyperbaric oxygen therapy and to evaluate wound healing progression using a new hyperspectral imaging technology.
- Trial name
- HBOT (NCT00768027)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- HyperMed
Lentigo Maligna
Photodynamic Therapy for Lentigo Maligna Using 5-aminolevulinic Acid Nanoemulsion as a Light Sensitizing Cream
This study investigates the efficacy of photodynamic therapy (PDT) in the treatment of lentigo maligna (LM). Hyperspectral imaging system (HIS) will be used to determine the margins of LM and to rule out possible invasion.
- Trial name
- LM PDT (NCT02685592)
- Testing
- 5-aminolevulinic acid nanoemulsion
- Where
- Finland
- Volunteers
- 10 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Chronic Limb Threatening Ischemia
Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy…
- Trial name
- NCT05786001
- Where
- Finland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tampere University
Lung Neoplasm, Pulmonary Metastasis
HSI for Intersegmental Plane Identification During Sublobar Pulmonary Resections
The purpose of this study is the identification of the intersegmental plane and navigation during sublobar pulmonary resections in lung cancer using Hyperspectral Imaging, the comparison with ICG fluorescence intersegmental plane…
- Trial name
- HYPER-Seg (NCT05676788)
- Testing
- Hyperspectral Imaging
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- LungenClinic Grosshansdorf
Actinic Keratoses
Daylight-mediated Photodynamic Therapy of Actinic Keratoses:Comparing 0.2%HAL With 16%MAL
This pilot study compares two photosensitizers, hexylaminolaevulinate (HAL) and methylaminolaevulinate (MAL), in treatment of actinic keratoses. Study is conducted using randomized split-face design.
- Trial name
- NCT02149342
- Testing
- Hexylaminolaevulinate cream, Methylaminolaevulinate cream
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Alzheimer Disease, Alzheimer Dementia
Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease
Because of a shared ontogenic origin, the retina displays similarities to the brain and spinal cord in terms of anatomy, functionality, response to insult, and immunology.
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Mild Cognitive Impairment, Dementia
- Trial name
- RetAD (NCT03466177)
- Testing
- Non-invasive, multimodal retinal imaging
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetic Complications, Foot Care
Evaluation of Materials for the Distribution of Pressure in the Treatment of Neuroischemic Ulcers
The hypothesis of this study is based on the premise that pressure-distributing materials with superior biomechanical and tissue response properties will be capable of improving the healing rate of neuropathic ulcers.
- Trial name
- NCT07620379
- Testing
- felt padding
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Colorectal Neoplasms, Colorectal Surgery
Intraoperative Hyperspectral Imaging for Laparoscopic Surgery
The study aims to evaluate the use of the HyperSnap Surgical System (HSS1) during laparoscopic surgeries, specifically in bowel resections and cholecystectomies.
- Conditions
- Colorectal Neoplasms, Colorectal Surgery, Cholecystitis, Cholecystectomy, Laparoscopic
- Trial name
- LapHSI (NCT06700317)
- Testing
- HSS1
- Volunteers
- 40 people
- Sponsor
- King's College London
Dry Eye
Evaluation of Dry Eye by Tear Film Imager in a Low Humidity Environmental Exposure Chamber (TFI-LH16)
The study consists of 3 study visits to the clinic over at least 9 days. Visit 1 - the medical screening visit: subjects will undergo informed consent and will be tested for signs and symptoms of Dry Eye Syndrome (DES) including…
- Trial name
- TFI-LH16 (NCT03061578)
- Testing
- Tear Film Imager, Low Humidity Environmental Exposure Chamber (LH-EEC)
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Adom Advanced Optical Technologies Ltd.
Diabetic Foot Ulcers
Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers
This study is designed to test a prototype imaging instrument that relies on Medical HyperSpectral Imaging (MHSI) technology for the assessment and prediction of diabetic foot ulceration and wound healing.
- Trial name
- NCT00617916
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- HyperMed
Parathyroid Diseases, Thyroid Diseases
Intraoperative EXamination Using MAChine-learning-based HYperspectral for diagNosis & Autonomous Anatomy Assessment
The intraoperative recognition of target structures, which need to be preserved or selectively removed, is of paramount importance during surgical procedures.
- Conditions
- Parathyroid Diseases, Thyroid Diseases, Liver Cancer, Liver Metastases
- Trial name
- iEXMachyna3 (NCT04589884)
- Testing
- Hyperspectral Imaging
- Where
- France
- Volunteers
- 112 people
- Sponsor
- IHU Strasbourg
Cholecystitis, Cholecystitis, Chronic
Shortwave Infrared Surgical Imaging Device Study
The goal of this observational study is to perform an in-human assessment of an investigational shortwave infrared (SWIR) imaging device, aimed to enhance the visualization of critical anatomical structures during surgical…
- Conditions
- Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism
- Trial name
- NCT07744425
- Testing
- Observational study of SWIR imaging device in surgery
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cision Vision, Inc.
Tissue Perfusion, Tumor
Tissue Characterization With Hyperspectral Imaging (HSI)
Hyperspectral Imaging (HSI) is a contact free method to analyse the from the tissue reflected light in the range of 500-1000nm. Aim of the study is to identify special reflex patterns to identify special tissue
- Conditions
- Tissue Perfusion, Tumor, Inflammation, Inflammatory Bowel Diseases
- Trial name
- HSIT (NCT04230603)
- Testing
- Hyperspectral imaging, Lactate acid measurement, pathological examination
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Cellulite, Gynoid Lipodystrophy
Quantitative Assessment of the Efficacy of Alidya
This study evaluated the efficacy of ALIDYA, a Class III medical device used in needle mesotherapy, for the treatment of cellulite (gynoid lipodystrophy) in women.
- Trial name
- NCT07675356
- Testing
- ALIDYA
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Alzheimer Disease, Dementia Alzheimers
Optical Coherence Tomography in Cerebral Amyloidosis
In this observational study, the investigators aim to evaluate whether changes in the retinal and choroidal circulation, as assessed by Optical Coherence Tomography (OCT) and the quantification of retinal amyloid deposits using…
- Conditions
- Alzheimer Disease, Dementia Alzheimers, Dementia, Lewy Body Disease
- Trial name
- NCT03472482
- Testing
- non-invasive retinal imaging
- Where
- Belgium
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Skin Aging, Photoaging
Effects of Stabilized Retinaldehyde on Aging Skin: A Split-Face Study
The goal of this clinical trial is to learn if retinaldehyde cream improves the appearance of aging skin in women aged 30 to 60 years.
- Trial name
- NCT07510165
- Testing
- Stabilized retinaldehyde 0.1%, Stabilized retinaldehyde 0.05%
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Macular Degeneration, Choroidal Neovascularization
Enhancing the Lucentis (Ranibizumab) Management of Choroidal Neovascular Membranes With Hyperspectral Imaging
Clinical trial investigating the role of hyperspectral imaging in the management of patients undergoing standard clinical treatment for naive neovascular choroidal membranes in age-related macular degeneration.
- Trial name
- NCT03105609
- Testing
- Hyperspectral imaging
- Where
- Australia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Eye Research Australia
Hyperspectral Imaging, Idiopathic Membranous Nephropathy
Study on the Application of Hyperspectral Imaging Technique in CTX Treatment of IMN
Investigators propose hyperspectral imaging analysis as a method to distinguish the efficacy of hormone-combined cyclophosphamide therapy for PMN, and classify sensitive and insensitive patients treated with hormone-combined…
- Conditions
- Hyperspectral Imaging, Idiopathic Membranous Nephropathy, Cyclophosphamide
- Trial name
- NCT05850845
- Testing
- Microscopic hyperspectral imaging system
- Volunteers
- 40 people
- Sponsor
- Qianfoshan Hospital
Preeclampsia (PE), Hypertensive Disorder of Pregnancy
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus.
- Trial name
- EPICS (NCT06912477)
- Testing
- Hyperspectral imaging, Further markers of endothelial dysfunction
- Where
- Germany
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Neurosurgery, Neurovascular
Intra-operative Hyperspectral Imaging in Neurosurgery
Brain surgery operations include brain tumour removal and blood vessel procedures. Each year in the UK, approximately 70,500 patients are diagnosed with a brain tumour, 5,000 of whom undergo surgery.
- Conditions
- Neurosurgery, Neurovascular, Neuro-Oncology
- Trial name
- NeuroHSI (NCT05294185)
- Where
- United Kingdom
- Volunteers
- 81 people
- Sponsor
- King's College London