Clinical trials: Hypertension, Pregnancy Induced
Hypertensive Disorders of Pregnancy (HDP), Maternal Health Care
Cost-Effectiveness of an mHealth Application in Pregnancy Care
Participants will be randomly assigned to either the intervention arm (mHealth application users) or the control arm, in which participants will record their data on paper or in Excel according to standard practice or the…
- Conditions
- Hypertensive Disorders of Pregnancy (HDP), Maternal Health Care, Mobile Health Technology (mHealth), Preeclampsia (PE)
- Trial name
- Penelope (NCT07621133)
- Testing
- mHealth application Penelope, Control
- Where
- Czechia
- Volunteers
- 166 people
- Sponsor
- Principal Engineering s.r.o.
Pregnancy Induced Hypertension
Optical Coherence Tomography Angiography Compared to Maternal Doppler in Screening for Hypertension in Pregnancy
Pregnancy related hypertension is one of the most prevalent obstetric complications. The aim of the study is to evaluate the validity and sensitivity of OCT angiography in prediction of pregnancy induced hypertensive disorders in…
- Trial name
- NCT05330949
- Testing
- Optical coherence Tomography Angiography, Uterine artry doppler
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Hypertension in Pregnancy
Hypertensive Disorders of Pregnancy - the Neonatal Burden of Disease
Around one in ten women have high blood pressure in pregnancy. This is potentially serious, with risks to the woman and her baby.
- Trial name
- NCT05015049
- Where
- United Kingdom
- Volunteers
- 823,957 people
- Sponsor
- Imperial College London
Hypertension, Cardiovascular Diseases
Hypertension Explored in Long-term Postpartum Follow-up in Later Life
The purpose of this study is to understand more about why women who have had hypertensive pregnancies may be at increased risk of high blood pressure and why these women are often at increased risk of heart and blood vessel…
- Conditions
- Hypertension, Cardiovascular Diseases, Cerebrovascular Disorders, Vascular Diseases
- Trial name
- HELPFUL (NCT06187012)
- Testing
- Hypertensive pregnancy
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Oxford
Preeclampsia
ECLAXIR:Search for an Association Between CX3CR1 V249I Polymorphism, Preeclampsia and Endothelial Injury
The study hypothesis is the involvement of the couple CX3CR1/CX3CL1 in occurrence of endothelial injury in preeclampsia. According to this hypothesis, Carriers of the I249 allele who express less CX3CR1 shoud be protected against…
- Trial name
- NCT00190177
- Where
- France
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vitamin D Deficiency, Pre Eclampsia
Evaluation of the Effectiveness of Vitamin D Supplementation to Pregnant Women and Their Infants in Pakistan.
Vitamin D deficiency is wide spread in South Asian population and is contributing to burden of disease in this region including Pakistan.
- Conditions
- Vitamin D Deficiency, Pre Eclampsia, Stillbirths, Low Birth Weight
- Trial name
- NCT01229189
- Testing
- Vitamin D
- Where
- Pakistan
- Volunteers
- 460 people
- Sponsor
- Aga Khan University
Preeclampsia, Pregnancy Related
Use of Lumella-glycosylated Fibronectin for Diagnosis of Preeclampsia
women with symptoms of preeclampsia from antenatal clinic or triage will be offered Lumella test along with traditional blood tests. If Lumella test is positive which will be compared with the traditional blood test results.
- Conditions
- Preeclampsia, Pregnancy Related, Hypertension
- Trial name
- Lumella (NCT06085001)
- Testing
- Lumella finger prick blood test
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Croydon University Hospital
Pregnancy, Preeclampsia
Influence of Physical Exercise on Endothelial Function in Pregnant Women
The purpose of this study is to determine the effect of regular aerobic exercise on endothelial function in pregnancy.
- Conditions
- Pregnancy, Preeclampsia, Exercise
- Trial name
- NCT00741312
- Testing
- Regular aerobic physical exercise, Activities of daily living
- Where
- Colombia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Infant,Premature, Bronchopulmonary Dysplasia
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW < 1500 g).
- Conditions
- Infant,Premature, Bronchopulmonary Dysplasia, Pulmonary Hypertension
- Trial name
- NCT03542812
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Eclampsia, Seizures
Comparing Intravenous and Intramuscular Magnesium Sulphate for Preventing Seizure Recurrence in Women With Eclampsia
The goal of this clinical study is to learn whether the way we give magnesium sulphate-into a vein (intravenous, IV) versus into a muscle (intramuscular, IM)-affects how often women with eclampsia have repeat seizures.
- Conditions
- Eclampsia, Seizures, Pregnancy
- Trial name
- NCT06997575
- Testing
- Magnesium Sulphate infusion, Magnesium sulphate intramuscular
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Nishtar Medical University
Pre Eclampsia
Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Pregnant Women
The purpose of the study is to help make a lower cost automatic blood pressure monitor device for diagnosis and monitoring of pre-eclampsia in pregnant women, where automatic blood pressure monitoring is limited or not available.
- Trial name
- NCT02319174
- Testing
- Sphygmo
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- William Marsh Rice University
Pre-Eclampsia
IMPACT OF THE BIOLOGICAL RATIO ON MEDICAL DECISION MAKING IN WOMEN SUSPECTED OF PREECLAMPSIA
Previous studies demonstrated that Placental Growth Factor (PIGF) and Vascular Endothelial Growth Factor (VEGF) produced by trophoblast cells decreases during Preeclampsia, whereas soluble fms-like tyrosine kinase-1 (sFlt-1), an…
- Trial name
- NCT06224946
- Testing
- soluble fms-like tyrosine kinase (sFlt-1) / placental growth factor (PlGF) ratio
- Where
- France
- Volunteers
- 314 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pre-Eclampsia
Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial
IMPROVE is a pilot RCT with a behavioral intervention component (CardioPrevent program). The primary objectives of this pilot study are to assess the feasibility of the implementation of a postpartum CVD prevention lifestyle…
- Trial name
- IMPROVE (NCT03302260)
- Testing
- CardioPrevent® Program
- Volunteers
- 84 people
- Sponsor
- University of Calgary
Infertility, Eclampsia Preeclampsia
Modelization of Early Endometrial-trophoblast Molecular Interaction
Despite significant advances in assisted reproductive technology, only 25% of in vitro fertilization (IVF) embryo transfers result in pregnancy, largely due to implantation failure.
- Trial name
- MEETMI (NCT07825649)
- Testing
- Diagnostic hysteroscopy with endometrial biopsy
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Preeclampsia, Recurrence
Effects of Recurrent PE on Women and Offspring
The purpose of this study is to evaluate the risk factors of recurrent preeclampsia and compare the short-term and long-term adverse outcomes of women and their offspring.
- Conditions
- Preeclampsia, Recurrence, Hypertension
- Trial name
- RPOH (NCT05134285)
- Testing
- blood pressure,BMI, blood sample
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dunjin Chen
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pre-Eclampsia
Are There Sleep-related Factors That Contribute to an Increased Incidence of Pre-eclampsia at Altitude?
Women at altitude have an increased incidence of pre-eclampsia. Populations at altitude have a greater incidence of sleep apnea. And women with sleep apnea are at increased risk of developing preeclampsia.
- Trial name
- NCT06702475
- Testing
- Home Sleep Test with Watch PAT-one
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Eclampsia, Severe Pre-eclampsia
Pulmonary Edema Resolution in Severe Preeclampsia and Eclampsia
Patients with severe preeclampsia or eclampsia suffer from pulmonary complications. Accurate assessment of patients with pulmonary involvement using lung ultrasound (LUS) and echocardiography could lead to earlier detection of…
- Trial name
- TiPER (NCT06219109)
- Where
- Sierra Leone
- Volunteers
- 55 people
- Sponsor
- Doctors with Africa - CUAMM
Preeclampsia, Obstetric Labor Complications
Pravastatin to Prevent Preeclampsia
This study is a double-blind randomized placebo-controlled trial of 1,550 high-risk women to assess whether daily treatment with pravastatin administered early in pregnancy reduces the rate of a composite outcome of preeclampsia…
- Conditions
- Preeclampsia, Obstetric Labor Complications, Hypertension in Pregnancy
- Trial name
- Pravastatin (NCT03944512)
- Testing
- Pravastatin
- Where
- 12 sites in United States
- Volunteers
- 102 people
- Sponsor
- The George Washington University Biostatistics Center
High Risk Pregnancy
Efficacy of Aspirin and L-arginine in High Risk Preeclamptic
Worldwide, the incidence of preeclampsia ranges from 2 to 10% of pregnancies. The World Health Organization (WHO) estimates that the incidence of preeclampsia is seven times higher in developing countries than in developed (2.8%…
- Trial name
- NCT02838030
- Testing
- L-arginine, acetylsalicylic acid
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- University of Guadalajara
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