Clinical trials: Hypertension, Pregnancy Induced
Preeclampsia
Standard 24-hour Urine Protein vs Shorter Period for Diagnosis of Pre-eclampsia
Background and project rationale: Preeclampsia is a common complication of pregnancy, affecting 6-8% of all pregnancies and constitutes a leading cause of maternal morbidity and mortality.
- Trial name
- PET and urine (NCT01881542)
- Where
- Israel
- Volunteers
- 307 people
- Sponsor
- HaEmek Medical Center, Israel
Pre Eclampsia
Transcranial Doppler in Preeclampsia and Its Complications.
Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality. It is defined by new-onset hypertension after 20 weeks of gestation, often associated with proteinuria and/or systemic complications such as…
- Trial name
- DTC-PE (NCT07646561)
- Testing
- Transcranial doppler ultrasound
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Preterm Birth, PPROM
Antenatal Breastmilk Expression in Pregnant Women at High Risk of Preterm Birth
In this randomized controlled study, the investigators aim to examine if antenatal breastmilk expression (aBME) from week 28 in high-risk pregnancies is a safe and effective method to ensure early access to mother's own milk.
- Conditions
- Preterm Birth, PPROM, Preeclampsia, Previous Preterm Birth
- Trial name
- EXPRESSMOM2 (NCT07191366)
- Testing
- Handstimulation of breast
- Volunteers
- 250 people
- Sponsor
- Odense University Hospital
Pre-Eclampsia, Frozen Embryo Transfer
Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer
Identifying modifiable factors that contribute to preeclampsia risk associated with assisted reproduction can improve maternal health.
- Trial name
- PREECLAM-2019 (NCT04092829)
- Testing
- FROZEN EMBRYO TRANSFER IN SUBSTITUTED CYCLE
- Where
- Spain
- Volunteers
- 591 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Pregnancy-Induced Hypertension
Slow and Deep Breathing to Lower Blood Pressure in Women With Pregnancy-induced Hypertension
This study evaluates the effect of slow and deep breathing on lowering blood pressure in women with pregnancy-induced hypertension.
- Trial name
- NCT04059822
- Testing
- Slow and deep breathing
- Where
- 2 sites in United Kingdom
- Volunteers
- 1 people
- Sponsor
- Bournemouth University
Pre-Eclampsia
Adipokines, Inflammation, Insulin Resistance and Endothelial Dysfunction in Preeclampsia
The aim of the present study is to evaluate the implication of adipokines, inflammation, insulin resistance and endothelial dysfunction in the pathogenesis of preeclampsia and in pregnancy related complications.
- Trial name
- NCT04455204
- Testing
- Serum asymmetteric dimethyl arginine, serum lipid profiles, Serum vaspin
- Volunteers
- 60 people
- Sponsor
- Tanta University
Mindfulness Breath Awareness Meditation, Preeclampsia
Mindfulness Breath Awareness Meditation and Preeclampsia
The effect of mindfulness breath awareness meditation on health profile, vital signs, and fetal heart rate in pregnant women with preeclampsia
- Trial name
- NCT06065709
- Testing
- Mindfulness breath awareness meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aysegul Kilicli
Pre-eclampsia
Saccadic Reaction Time and Preterm Pre-eclampsia
This study is recruiting two groups of women over the age of 18; those who are pregnant and who have pre-eclampsia; and those who are pregnant but do not have pre-eclampsia.
- Trial name
- NCT02613793
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Vitamin D Deficiency, Pre-Eclampsia
Vitamin D Level and Its Relation to Pre-eclampsia and Eclampsia
To compare 25(OH)D level in patients with pre-eclampsia, eclampsia and normotensive pregnant women as well as to study the prevalence of Vitamin D deficiency among the 3 groups.
- Conditions
- Vitamin D Deficiency, Pre-Eclampsia, Eclampsia, Antepartum
- Trial name
- NCT03882099
- Testing
- Determination of Vitamin D by ELISA
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Leiden Factor V Deficiency,Preeclampsia, Doppler Examination
Prediction of Outcome in Severe Preeclampsia
this summary studied the predictive values of factor V Leiden mutation , doppler indices , placental pathology to unfavorable fetal and maternal outcomes
- Conditions
- Leiden Factor V Deficiency,Preeclampsia, Doppler Examination, Palental Pathology
- Trial name
- NCT03871764
- Testing
- blood sample , doppler of uterine vessel and placenta
- Volunteers
- 100 people
- Sponsor
- Cairo University
Pre-Eclampsia, Depression
Preeclampsia Research on Vitamin D, Inflammation, & Depression
This study is designed to comprehensively investigate the anti-inflammatory role of vitamin D in reproductive aged women, and its association with preeclampsia and depression.
- Conditions
- Pre-Eclampsia, Depression, Inflammation, Vitamin D Deficiency
- Trial name
- PROVIDE (NCT03018132)
- Testing
- mental health screening, education and referral program
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pre-Eclampsia; Complicating Pregnancy, Antiphospholipid Syndrome in Pregnancy
Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure
The primary goal of this observational study is to learn about postpartum pulmonary artery pressure in women who suffered from Preeclampsia and Antiphospholipid Syndrome.
- Conditions
- Pre-Eclampsia; Complicating Pregnancy, Antiphospholipid Syndrome in Pregnancy, Pulmonary Hypertension
- Trial name
- NCT05679206
- Testing
- Echocardiography images, 24-hour ambulatory blood pressure monitoring
- Where
- Switzerland
- Volunteers
- 900 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pre-Eclampsia
Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy
Relation of certain maternal serum antibodies to Doppler changes will be studied in cases suffering from hypertension with pregnancy.
- Trial name
- NCT03214393
- Testing
- Doppler, serum antibodies
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Pre-Eclampsia
Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study
To find out if lower levels of vitamin D is more prevalent in preeclamptic women
- Trial name
- NCT02677233
- Volunteers
- 90 people
- Sponsor
- Ain Shams Maternity Hospital
Gestational Hypertension, Hypertension in Pregnancy
A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)
This trial is a pilot-scale, single institution randomized, placebo-controlled trial to assess the feasibility, acceptability, and efficacy of administering dapagliflozin for cardiovascular risk reduction in the postpartum…
- Conditions
- Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia
- Trial name
- DAPA-HP (NCT06785116)
- Testing
- Dapagliflozin 10mg Tab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Pre-Eclampsia
Prospective Case-Control Study of Cardiovascular Changes in Pregnancy Related Hypertensive Disorders
This is a research study to understand the changes in the heart and the cardiovascular system that may occur in women who develop high blood pressure during pregnancy.
- Trial name
- ARTSEN (NCT04713228)
- Testing
- ARTSENS Pen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Obesity, Gestational Diabetes
Postprandial Walking in Obese Pregnant Women and Perinatal Outcomes - a Multicenter Randomized Clinical Trial
The purpose of this study is to verify if postprandial walks are effective in obese pregnant women, as regards to gestational weight gain and typical diseases of that period, as gestational diabetes and preeclampsia.
- Conditions
- Obesity, Gestational Diabetes, Preeclampsia
- Trial name
- NCT02180152
- Testing
- Postprandial walks
- Where
- Brazil
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Preeclampsia, Hypertensive Disorder of Pregnancy
Progesterone Preeclampsia
This randomized controlled trial evaluates whether nightly vaginal micronized progesterone (400 mg) initiated before 12 weeks' gestation reduces the incidence of preeclampsia in low-risk pregnant individuals.
- Trial name
- NCT07448597
- Testing
- Progesterone supplementation
- Where
- United States
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pre-Eclampsia, Eclampsia
Catestatin and Hypertension in Pregnancy
Catestatin is a kind of protein involved with cardiovascular disease. Accumulated evidence shows that Catestatin may be a predictor of primary hypertension, but whether it plays the same role in pregnant hypertensive disorders…
- Conditions
- Pre-Eclampsia, Eclampsia, Hypertension, Pregnancy-Induced, Hypertension in Pregnancy
- Trial name
- NCT03200743
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yuchen Pan
Hypertension, Pregnancy-Induced
Comparison of Urine Protein/Creatinine Ratio With 24-hour Urine Protein Excretion in Woman With Hypertensive Disorders
The presence of proteinuria (>300 mg/d) represents an important factor in the diagnosis and evaluation of the pregnant patient with an hypertensive disorder.
- Trial name
- NCT01508208
- Testing
- Hypertensive disorder of pregnancy
- Where
- Panama
- Volunteers
- 420 people
- Sponsor
- Saint Thomas Hospital, Panama
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