Clinical trials: Hypertension, Renal
Hypertension
Renal Denervation for Management of Drug-Resistant Hypertension
INSPiRED is a multicenter parallel-group trial comparing usual medical treatment (control group) or usual medical treatment plus renal denervation (intervention).
- Trial name
- INSPiRED (NCT01505010)
- Testing
- Renal denervation
- Where
- 2 sites in Belgium
- Volunteers
- 17 people
- Sponsor
- KU Leuven
Type 2 Diabetes
Time Course of the Blood Pressure Lowering Effect of Liraglutide Therapy in Type 2 Diabetes
Background: Preclinical blood pressure (BP) data from studies of hypoglycemic effects of liraglutide treatment (the LEAD program), revealed a significant antihypertensive potential.
- Trial name
- Liratime (NCT01499108)
- Testing
- liraglutide
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Peter Rossing
Renal Insufficiency, Chronic, Hypertension
Supporting Self-Management of Healthy Behaviors in Diabetes, Kidney Disease, and Hypertension
The planned intervention, entitled, Supporting Self-Management of Health Behaviors to Optimize Health (SMART-HABITS for Health), aims to provide support for patients with chronic kidney disease (CKD), hypertension and diabetes by…
- Conditions
- Renal Insufficiency, Chronic, Hypertension, Diabetes
- Trial name
- NCT05565716
- Testing
- Support Person, Social Norms
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Pennsylvania
Hypertension
Effects of Electrical Baroreflex Stimulation on Sympathetic Activity, Renal Hemodynamics, and Insulin Sensitivity
Electrical stimulation of carotid baroreceptors (baropacing) acutely decreases arterial pressure in patients with refractory hypertension.
- Trial name
- CVRX-ReSy (NCT01355510)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Hannover Medical School
Uncontrolled Hypertension, Renal Denervation
Renal Denervation in Chronic Kidney Disease - RDN-CKD Study
RDN-CKD Study is a prospective, randomized (1:1, central randomization), double-blind (unblinded interventionalist and blinded study team at each center), sham controlled, multicenter feasibility study.
- Conditions
- Uncontrolled Hypertension, Renal Denervation, Chronic Kidney Disease stage3
- Trial name
- RDN-CKD (NCT04264403)
- Testing
- Renal denervation
- Where
- 4 sites in Germany
- Volunteers
- 44 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Kidney Diseases, Hypertension
Nephrospec Switzerland
This is a randomized, double-blind sham-controlled monocentric trial. 30 patients that are diagnosed with hypertension and with moderate to severe chronic kidney disease are included in this trial.
- Trial name
- NCT06194591
- Testing
- NephrospecTM, low-intensity extracorporal shockwave therapy device
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Menno Pruijm
Hypertension, Chronic Kidney Disease
Renal Nerve Ablation in Chronic Kidney Disease Patients
In patients with treatment resistent hypertension renal nerve ablation emerged as an effective interventional approach of treating hypertensive disease with a progressively increasing fall in blood pressure.
- Trial name
- NCT01442883
- Testing
- Simplicity Catheter
- Where
- 2 sites in Germany
- Volunteers
- 27 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Healthy, Renovascular Hypertension
Magnetic Resonance Imaging for Evaluating Kidney Function
Renovascular hypertension (RVH) is a potentially curable disease affecting 0.5-5 percent of patients with hypertension. The current diagnostic work-up of RVH involves a complex algorithm which includes doppler ultrasound…
- Trial name
- NCT00006173
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Kidney Failure, Hypertension
Cardiovascular-Renal Consequences of Reducing Renal Mass After Living Kidney Donation
A reduce in renal mass may result in remnant single nephron hyperfiltration, with associated proteinuria and an accelerated loss of kidney function.
- Conditions
- Kidney Failure, Hypertension, Albuminuria, Renal Failure
- Trial name
- NCT01564966
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University
Hypertension, Renal
Effect of Amlodipine Versus Bisoprolol on Hypertensive Patients With End-stage Renal Disease on Maintenance Hemodialysis.
Hypertension is highly prevalent in hemodialysis (HD) patients and leads to increased morbidity and mortality due to cardiovascular disease(CVD).
- Trial name
- NCT04085562
- Testing
- Bisoprolol Fumarate 5-10 mg, Amlodipine 5-10 mg
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Alexandria University
Hypertension
Sham Controlled Study of Renal Denervation for Subjects With Uncontrolled Hypertension
To demonstrate that non-invasive renal denervation is safe and shows a net difference in blood pressure reduction when compared to sham in subjects with uncontrolled hypertension.
- Trial name
- WAVE_IV (NCT02029885)
- Testing
- Investigational Therapy (Surround Sound)
- Where
- 28 sites in Australia, Austria and 6 more
- Volunteers
- 132 people
- Sponsor
- Kona Medical Inc.
Blood Pressure
The Influence of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Renal Function in Patients Undergoing Non-emergent Coronary Angiography
The aim of the current study is to evaluate prospectively whether concomitant administration of RAAS blockers (namely ACE-I and ARBs') influence the change in estimated GFR (eGFR) after administration of contrast media in…
- Trial name
- NCT01071642
- Testing
- stop ace-i/arb 24 h before procedure and restarted 24 hours after the procedure, ACE/ARB stopped 24 hours before procedure and start immediately after
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center
Chronic Kidney Diseases, Hypertension
Green Propolis Extract and Royal Jelly in Hypertensive Patients and/or With Chronic Kidney Disease
This work aims to evaluate the effects of the association of green propolis extract with royal jelly on inflammation and oxidative stress in participants with chronic kidney diseases (CKD) and Systemic arterial hypertension…
- Conditions
- Chronic Kidney Diseases, Hypertension, Cardiovascular Diseases
- Trial name
- NCT06288204
- Testing
- Propolis associated with Royal Jelly, Royal Jelly
- Where
- 2 sites in Brazil
- Volunteers
- 153 people
- Sponsor
- Universidade Federal Fluminense