Clinical trials: Hypertension Emergency
Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
PERSEUS is an academic, investigator-initiated, multicenter observational registry of adults with acute pulmonary embolism (PE), promoted by Azienda Ospedaliero-Universitaria Careggi (Florence, Italy).
- Conditions
- Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension, Right Ventricular Dysfunction, Pulmonary Embolism (PE)
- Trial name
- PERSEUS (NCT07855679)
- Testing
- Routine clinical care (no study intervention)
- Where
- 16 sites in Italy, Poland and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Hypertensive Urgency, Primary Hypertension
The Use of Virtual Reality and Music Therapy for Hypertensive Urgency
This study aims to evaluate whether virtual reality (VR) and classical music therapy, when added to standard antihypertensive treatment, can improve blood pressure control and reduce anxiety in patients presenting to the…
- Trial name
- NCT07272486
- Testing
- Captopril 25Mg Tab, Virtual Reality Exposure, Classic Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara City Hospital Bilkent
Hypoxemic Respiratory Failure, Side Effect
Clinical Relevance of Nicardipine Induced Hypoxemia in the Intensive Care Unit
In the context of postoperative hypertension in the intensive care units, or after resusitation of hypertensive patients, intravenous antihypertensive drugs are often used.
- Conditions
- Hypoxemic Respiratory Failure, Side Effect, Hypertensive Emergency
- Trial name
- ECRHIN-ICU (NCT05155202)
- Testing
- Antihypertensive Agents
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Hypertension, Acute Severe Hypertension
Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.
- Conditions
- Hypertension, Acute Severe Hypertension, Hypertensive Emergency, Hypertensive Urgency
- Trial name
- KARDINAL-ASH (NCT07511361)
- Testing
- Tonlamarsen
- Where
- 13 sites in United States
- Volunteers
- 140 people
- Sponsor
- Kardigan, Inc.
Hypertension, Cardiovascular Diseases
Targeting of UnControlled Hypertension in Emergency Department
The proposed project underscores the following: 1) The prevalence of uncontrolled/undiagnosed hypertension (HTN) in underrepresented groups presenting to the ED is alarmingly high, and 2) ED engagement and early risk…
- Conditions
- Hypertension, Cardiovascular Diseases, Vascular Diseases
- Trial name
- TOUCHED (NCT03749499)
- Testing
- HTN Educational Video, Visual Echocardiogram Image Clips, Mobile Health and Remote BP monitoring
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- University of Illinois at Chicago
Hypertension
TEC4Home Blood Pressure Randomized Controlled Trial
The goal of this clinical trial is to evaluate the effect of home blood pressure telemonitoring (HBPT) and case management (CM), relative to usual care, for improving blood pressure (BP) control among patients with high blood…
- Trial name
- NCT06303206
- Testing
- Home Blood Pressure Telemonitoring (HBPT) + Case Management (CM)
- Volunteers
- 408 people
- Sponsor
- University of British Columbia
Intra-Abdominal Hypertension, Respiratory Mechanics
Intra-Abdominal Pressure, Respiratory Mechanics, and Ventilator Liberation After Emergency Major Laparotomy
This prospective observational cohort study aims to investigate the relationship between intra-abdominal pressure (IAP), respiratory system mechanics, and successful liberation from invasive mechanical ventilation in adult…
- Conditions
- Intra-Abdominal Hypertension, Respiratory Mechanics, Mechanical Ventilation
- Trial name
- IAP-VENT (NCT07889609)
- Testing
- Serial Intra-Abdominal Pressure and Respiratory Mechanics Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Myocardial Infarction, Decompensated Chronic Heart Failure
Pre-discharge Influenza Vaccination in Patients Hospitalized for Acute Cardiac Conditions
Patients hospitalized for acute cardiac conditions-including acute myocardial infarction, acute heart failure, pulmonary embolism, arrhythmias, and hypertensive emergencies-represent a heterogeneous population at very high risk…
- Conditions
- Myocardial Infarction, Decompensated Chronic Heart Failure, Acute Heart Failure (AHF), Pulmonary Embolism Acute
- Trial name
- NCT07617376
- Testing
- Influenza vaccination
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Wroclaw Medical University
Acute Coronary Syndromes, Heart Failure
Prospective Cohort of Acute Cardiology Referrals in an Ambulatory Day-Hospital Setting
Suspected acute or subacute cardiovascular diseases-including chest pain, dyspnea, and palpitations-are among the most common reasons for unscheduled emergency department visits and pre-hospital referrals.
- Conditions
- Acute Coronary Syndromes, Heart Failure, Pulmonary Embolism, Deep Vein Thrombosis, HTN-Hypertension
- Trial name
- CESAR (NCT07675434)
- Volunteers
- 25,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
Effective interventions that can address uncontrolled hypertension, particularly in underrepresented populations that use the emergency department (ED) for primary care, are critically needed.
- Trial name
- AHEAD2 (NCT03093532)
- Testing
- ED SBIRT-HTN, PACHT-c
- Volunteers
- 150 people
- Sponsor
- University of Illinois at Chicago
Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension
Remote Postpartum Blood Pressure Monitoring and Cardiovascular Education
The goal of this clinical trial is to learn if patient education and regular text reminders are a feasible intervention to engage patients and reduce post partum hypertension.
- Trial name
- NCT06920563
- Testing
- Video, Text Reminder, Blood pressure threshold
- Where
- United States
- Volunteers
- 296 people
- Sponsor
- Ochsner Health System
Hypertension, Self-Care Practices
Telemedicine-Based Behavioral Intervention to Improve Self-Care Among Hypertensive Patients
The goal of this quasi-experimental clinical study is to learn whether a telemedicine-based behavioral intervention can improve self-care practices among adult patients with hypertension receiving care at teaching hospitals in…
- Conditions
- Hypertension, Self-Care Practices, Medication Adherence, Hospital Admission
- Trial name
- NCT07412106
- Testing
- Telemedicine-Based Behavioral Counseling
- Volunteers
- 320 people
- Sponsor
- Bahir Dar University
Traumatic Brain Injury
Measurement of Optic Nerve Sheath in Traumatic Raised Intracranial Pressure
Trauma patients are at risk for serious head trauma. The consequences of serious head trauma are often life altering. Currently, the only method available to rapidly assess the severity of head injury and need for neurosurgical…
- Trial name
- MOONSTRIP (NCT00783809)
- Where
- Canada
- Volunteers
- 560 people
- Sponsor
- McMaster University
Cardiovascular Diseases, Heart Diseases
Epidemiology of Hypertensive Emergency
To test the hypotheses that hypertensive emergency was associated with non-compliance with antihypertensive medication, low level of contact with the medical care system, and alcohol abuse and cigarette smoking.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005240
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Columbia University
Traumatic Brain Injury
TCD and ONSD for Early Risk Stratification of Traumatic Brain Injury
This observational study aims to evaluate the combined use of transcranial Doppler (TCD) and optic nerve sheath diameter (ONSD) ultrasound for early risk stratification of adults with traumatic brain injury (TBI) presenting to…
- Trial name
- TCD-ONSD (NCT07820527)
- Testing
- Transcranial Doppler and Optic Nerve Sheath Diameter Assessment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypertension, Hypertensive Crisis
Improving Acute Hypertension Management Through Emergency Department Checklist
The investigators hypothesize that the implementation of a checklist in acute severe hypertension would result in improving short and long-term outcomes of patients with acute severe hypertension treated in the emergency…
- Conditions
- Hypertension, Hypertensive Crisis, Hypertensive Emergency
- Trial name
- NCT04553653
- Testing
- checklist
- Where
- Pakistan
- Volunteers
- 1,161 people
- Sponsor
- Johns Hopkins University
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asymptomatic Hypertension
Innovative Approaches to Hypertension Management in High-Risk Emergency Department Populations
This single-center, single-arm quasi-experimental study will assess the feasibility and acceptability of a community health worker (CHW)-led intervention to address social determinants of health (SDOH) among emergency department…
- Trial name
- aHTN-Manage (NCT07539597)
- Testing
- Community Health Worker engagement
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension, Hyperglycemia
Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial
The objective of this study is to pilot a multifaceted, optimized intervention for metabolic syndrome (MetS) in emergency department patients to establish feasibility.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia, Metabolic Syndrome
- Trial name
- METS (NCT07119658)
- Testing
- Composite intervention to address MetS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University