Clinical trials: Hypertensive Crisis
Hypertensive Emergency
a Study Evaluating the Safety and Efficacy of Clevidipine for Patients Who With Hypertensive Emergency and Sub-emergency
A Multicentre, Randomized, Double-blind, Parallel Design Phase III Study to Evaluate the efficacy and safety of QLG2071 Versus Cleviprex® in the Treatment of Hypertensive Emergency and Sub-emergency
- Trial name
- NCT05922436
- Testing
- QLG2071, Cleviprex®
- Volunteers
- 378 people
- Sponsor
- Qilu Pharmaceutical (Hainan) Co., Ltd.
Hypertensive Emergency, Hypertensive Urgency
Telemedical Versus Conventional Emergency Care of Hypertensive Emergencies
Comparison of telemedical prehospital emergency care and conventional on-scene physician based care of hypertensive emergencies and urgencies. The adherence to current Guidelines should be researched.
- Trial name
- NCT02924805
- Testing
- Telemedical care
- Where
- Germany
- Volunteers
- 331 people
- Sponsor
- RWTH Aachen University
Hypertensive Urgency
Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate
Hypertensive urgency (HT urgency) is an alarm sign of uncontrolled hypertension. It can be aggravated by nonadherent to medication and psychosocial stress.
- Trial name
- NCT04572672
- Testing
- Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Khon Kaen University
Hypertension, Hypertensive Crisis
Improving Acute Hypertension Management Through Emergency Department Checklist
The investigators hypothesize that the implementation of a checklist in acute severe hypertension would result in improving short and long-term outcomes of patients with acute severe hypertension treated in the emergency…
- Conditions
- Hypertension, Hypertensive Crisis, Hypertensive Emergency
- Trial name
- NCT04553653
- Testing
- checklist
- Where
- Pakistan
- Volunteers
- 1,161 people
- Sponsor
- Johns Hopkins University
Hypertensive Urgency, Primary Hypertension
The Use of Virtual Reality and Music Therapy for Hypertensive Urgency
This study aims to evaluate whether virtual reality (VR) and classical music therapy, when added to standard antihypertensive treatment, can improve blood pressure control and reduce anxiety in patients presenting to the…
- Trial name
- NCT07272486
- Testing
- Captopril 25Mg Tab, Virtual Reality Exposure, Classic Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara City Hospital Bilkent
Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Hemolytic and uremic syndrome (HUS) is a clinic-biological syndrome related to thrombotic microangiopathy affecting predominantly the kidney.
- Trial name
- HYPERSHU (NCT05726916)
- Testing
- Soliris®, Renin angiotensin system blockers
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertensive Emergency, Hypertension
A ED-based Intervention to Improve Antihypertensive Adherence
Despite great strides, hypertension remains an incredibly important disease and public health problem. This study addresses this critical need among ED patients, a unique population of patients who are (a) likely to benefit from…
- Conditions
- Hypertensive Emergency, Hypertension, Blood Pressure
- Trial name
- NCT02672787
- Testing
- ED-based behavioral intervention, ED usual care plus education
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Vanderbilt University
Hypertension
Awareness Program on Knowledge Regarding Prevention of Hypertensive Crisis
To determine the effect of planned awareness program on knowledge regarding prevention of hypertensive crisis in hypertensive patients.
- Trial name
- NCT06986746
- Testing
- Hypertension Crisis Awareness Program
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Riphah International University
Pulmonary Hypertension
Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)
This study was designed to investigate treatment of postoperative pulmonary hypertension by iloprost inhalation in children with congenital heart defects.
- Trial name
- NCT01598441
- Testing
- iloprost nebuliser solution, distilled water
- Where
- 3 sites in China
- Volunteers
- 8 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Infection, Heart Failure
Home Hospital for Suddenly Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03524222
- Testing
- Home Hospitalization
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Brigham and Women's Hospital
Pulmonary Hypertension
Study of Inhaled Iloprost in Pediatric Pulmonary Hypertension (PH) After Surgery
The aim of this study is to determine whether inhaled iloprost can be used to prevent and treat PH and PHC while in children after operation of CHD
- Trial name
- NCT01310751
- Testing
- iloprost nebuliser solusion, distilled water
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hypertensive Urgency
Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department
The purpose of this study is to compare the safety and efficacy of Cardene I.V. to labetalol administered intravenously for the management of hypertension in the emergency department setting.
- Trial name
- CLUE (NCT00765648)
- Testing
- nicardipine intravenous, Labetalol
- Where
- 2 sites in United States
- Volunteers
- 226 people
- Sponsor
- The Cleveland Clinic
Pulmonary Hypertensive Crisis
Effects of Saline on Circulation in Children
Pulmonary hypertensive crisis is a life-threatening condition, in which the blood pressure in the pulmonary artery, vein, and capillaries.
- Trial name
- NCT01668277
- Testing
- 7.2% NaCl, 0.9% NaCl
- Where
- 2 sites in Canada
- Volunteers
- 15 people
- Sponsor
- The Hospital for Sick Children
Acute Ischemic Stroke, Hypertensive Crisis
Nicardipine vs. Labetalol
In this ED-based study, the investigators compared the time to reach target blood pressure (BP) between hypertensive patients with acute ischemic stroke (AIS) undergoing intravenous (IV) thrombolysis and/or mechanical…
- Trial name
- AISstdy (NCT07277283)
- Testing
- nicardipine intravenous, labetalol intravenous
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Haseki Training and Research Hospital
Infection, Heart Failure
Serum Potassium Prediction Using Machine Learning and Single-lead ECG
This is a retrospective study drawing on data from the Brigham and Women's Hospital Home Hospital Program's Database. Sociodemographic and clinical data from a training cohort were used to train a machine learning algorithm to…
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT07493798
- Testing
- Potassium estimation algorithm
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Pulmonary Arterial Hypertension
Management of Acute Pulmonary Hypertensive Crisis in Children With Known Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a disease where the blood pressure in the pulmonary arteries (PAP) is high. PAH increases the risk of adverse events, including death, during and or after procedures.
- Trial name
- NCT05439460
- Testing
- Phenylephrine, Epinephrine, Arginine Vasopressin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Hypertension, Acute Severe Hypertension
Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.
- Conditions
- Hypertension, Acute Severe Hypertension, Hypertensive Emergency, Hypertensive Urgency
- Trial name
- KARDINAL-ASH (NCT07511361)
- Testing
- Tonlamarsen
- Where
- 13 sites in United States
- Volunteers
- 140 people
- Sponsor
- Kardigan, Inc.